The relationship between indicators of cardiac hemodynamics and types of dyslipidemia in patients with coronary heart disease and type 2 diabetes mellitus

Authors

  • A. О. Sypalo Kharkiv National Medical University, Kharkiv,
  • P. G. Kravchun Kharkiv National Medical University, Kharkiv,
  • O. I. Kadykova Kharkiv National Medical University, Kharkiv,

DOI:

https://doi.org/10.14739/2310-1210.2017.3.100577

Keywords:

myocardial ischemia, diabetes mellitus type 2, dyslipidemias, hemodynamics

Abstract

The purpose of this study was to evaluate the relationship between indicators of cardiac hemodynamics and types of dyslipidemia in patients with coronary heart disease and type 2 diabetes mellitus.

Materials and Methods. A comprehensive examination of 85 patients with CHD and type 2 diabetes mellitus who were treated in the Cardiology Department of the Kharkiv City Clinical Hospital № 27 as a basic medical institution of the Department of Internal Medicine № 2 and Clinical Smmunology and Allergology of Kharkiv National Medical University MOH of Ukraine was made. Types of dyslipidemia were determined using the hyperlipidemia classification by WHO, based on the classification by Fredrickson (D. Fredrickson). The echocardiography study was performed according to standard methods (H. Feigenbaum, 1999) by the ultrasound unit RADMIR (Ultima PRO 30) (Kharkiv,Ukraine).

Results. As a result of our research it has been found a significant increase in such indicators of cardiac hemodynamics as EDV by 29.32%, CSR by 35,39%, ESV by 13.79%, EDS by 16.17% in the group of patients with coronary heart disease and type 2 diabetes mellitus with type IIb dyslipidemia compared with patients with coronary heart disease and type 2 diabetes mellitus with type IIa dyslipidemia. We have determined the cardio hemodynamics indexes in patients with coronary heart disease and type 2 diabetes mellitus with type I and type IV dyslipidemia and detected a significant increase in such indices as DBP by 15.49%, EDV by 26.99%, EDS by 13.49%, ESV by 16.57% and the diameter of the aorta by 9.85% compared with patients with coronary artery disease and type 2 diabetes mellitus with I type dyslipidemia.

Conclusions. According to the results of our study significant changes in the indices of cardiac hemodynamics occurred more often in patients with IIb and type IV dyslipidemia, suggesting a more adverse impact of these types on left ventricular remodeling in patients with coronary heart disease and type 2 diabetes mellitus.

References

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How to Cite

1.
Sypalo AО, Kravchun PG, Kadykova OI. The relationship between indicators of cardiac hemodynamics and types of dyslipidemia in patients with coronary heart disease and type 2 diabetes mellitus. Zaporozhye Medical Journal [Internet]. 2017May5 [cited 2024Nov.2];(3). Available from: http://zmj.zsmu.edu.ua/article/view/100577

Issue

No. 3 (2017)

Section

Original research

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