Some aspects of circular depressive disorders pathomorphosis at present
DOI:
https://doi.org/10.14739/2310-1210.2017.3.100837Keywords:
depressive disorder, age factors, statisticsAbstract
The article analyzes features of circular depressive disorders socio-demographic and clinical pathomorphosis in period of 1971 to 2016.
The aim of the work was to study the features of circular depressive disorders pathomorphosis at present.
Materials and Methods. Medical records of patients with circular depressive disorders, which were first diagnosed with a depressive disorder, were studied in our research: in period of 1971–1990 – 106 people, in period of 1991–2010 – 198 people, in period of 2011–2016 – 99 people.
Results. It has been found that there was a tendency of age pathomorphosis, which is significantly (p < 0.05) earlier age of onset and wider age range of depressive disorders debut (in 197–1990 – 39.9 ± 9.2, 38.0 [34.0–43.0] years; in 1991–2010 – 36.6 ± 9.7, 36.0 [30.0–44.0] years; in 2011–2016 – 34.5 ± 12.3, 30.0 [25.0–44.0] years; gender pathomorphosis – general trend towards an increase in the amount of women (respectively, 59.4 %, 70.2 % and 67.7 %). Socio-demographic pathomorphosis was associated with certain general social trends: a significant (p < 0.05) decrease in percentage of people with incomplete secondary education (7.5 %, 4.5 % and 2.0 % respectively), secondary education (34.0 %, 31.3 % and 20.2 %) and vocational education (31.1 %, 17.4 % and 16.2 % respectively) with an increase in percentage of people with incomplete higher education (respectively 2.8 %, 6.6 % and 14.1 %) and higher education (15.2 %, 27.3 % and 29.3 % respectively); as well as decrease in percentage of workers (44.3 %, 18.2 % and 7.1 % respectively) and agricultural workers (24.5 %, 13.1 % and 12.1 % respectively) with an increase in percentage of students (1.9 %, 4.5 % and 6.1 % respectively), servicemen (law enforcement officers) (0.9 %, 1.5 % and 5.1 % respectively) and the unemployed (0.0 %, 38.0 % and 43.3 % respectively).
Clinical pathomorphism of initial stage was characterized by an increase of nonspecific symptoms (24.5 %, 35.9 % and 39.4 % respectively), including emotional hyperesthesia (22.6 %, 33.8 % and 39.4 % respectively), asthenia (21.7 %, 31.8 % and 39.4 %), vegetative symptoms (20.8 %, 30.3 % and 35.4 % respectively) and sleeping disorders (21.7 %, 31.3 % and 34.3 %).
Clinical pathomorphosis of manifest stage showed a decreased percentage of apathetic and asthenic manifestations (96.2 %, 94.4 % and 87.9 % respectively) with an increase of anxiety disorders (41.5 %, 52.5 % and 64.6 % respectively), vegetative symptoms (59.4 %, 70.7 % and 80.8 % respectively) and sleeping disorders (85.8 %, 98.5 % and 99.0 % respectively).
Conclusions. These data suggest the presence of socio-demographic and clinical pathomorphosis of circular depressive disorders.
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