Results of clinical approbation of new local treatment method in the complex therapy of inflammatory parodontium diseases

Authors

  • Yu. G. Romanova Odesa National Medical University, Ukraine,
  • L. S. Kravchenko Odesa National Medical University, Ukraine,
  • I. V. Gerasymova Odesa National Medical University, Ukraine,
  • O. N. Davidenko Odesa National Medical University, Ukraine,
  • S. N. Koval Odesa National Medical University, Ukraine,

DOI:

https://doi.org/10.14739/2310-1210.2017.4.104920

Keywords:

apigel, magnetotherapy, microcirculation, periodontal diseases

Abstract

Treatment and prevention of inflammatory diseases of parodontium are one of the most difficult problems in stomatology today.

Purpose of research: estimation of clinical efficiency of local combined application of developed agent apigel for oral cavity care and low-frequency electromagnetic field magnetotherapy at treatment of inflammatory diseases of parodontium.

Materials and methods: 46 patients with chronic generalized catarrhal gingivitis and chronic generalized periodontitis of 1st degree were included into the study. Patients were divided into 2 groups depending on treatment management: basic (n = 23) and control (n = 23). Conventional treatment with the local use of the dental gel with camomile was used in the control group. Patients of the basic group were treated with local combined application of apigel and magnetotherapy. Efficiency was estimated with clinical, laboratory, microbiological and functional (ultrasonic Doppler examination) methods of examination.

Results: The application of the apigel and pulsating electromagnetic field in the complex medical treatment of patients with chronic generalized periodontitis (GhGP) caused positive changes in clinical symptom and condition of parodontal tissues, that was accompanied by decline of hygienic and parodontal indexes. As compared with patients who had traditional anti-inflammatory therapy, patients who were treated with local application of apigel and magnetoterapy had decline of edema incidence. It was revealed that decrease of the pain correlated with improvement of hygienic condition of oral cavity and promoted prevention of bacterial contamination of damaged mucous membranes. Estimation of microvasculatory blood stream with the method of ultrasonic doppler flowmetry revealed more rapid normalization of volume and linear high systole, speed of blood stream in the parodontal tissues in case of use of new complex local method.

Conclusions: Effect of the developed local agent in patients with inflammatory diseases of parodontium restore gingival sulcus microbiocenosis and structural-functional state of parodontium.

References

Grudyanov, A. I., Boriskina, O. A., & Rebrikov, D. V. (2011). Sootnosheniye patogennykh predstavitelej mikrobiocenoza parodontal'nykh karmanov pri raznoj stepeni tyazhesti parodontita [Correlation of pathogenic representatives of microbiocenosis of parodontal pockets under different degree of periodontitis severity]. Akta natura, 2, 101–104. [in Russian].

Levickij, A. P. (2011). Fiziologicheskaya mikrobnaya sistema polosti rta [Physiological microbial system of oral cavity]. Visnyk stomatolohii, 1, 6–11. [in Russian].

Kravchenko, L. S., & Solodenko, H. M. (patentee) (2014) Patent Ukrainy 94885 MPK (2014.01) A61K31/00, A61K35/00. Hel dlia likuvannia reaktsii slyzovoi obolonky porozhnyny rota na promenevu terapiiu [Ukraine Patent 94885 IPC (2014.01) A61K31 / 00, A61K35 / 00. Gel for treating reaction of oral mucosa with radiation therapy]. Biuleten, 29. [in Ukrainian].

Borisenko, A. G. (2011). E´ffektivnost' nekotorykh klinicheskikh indeksov v opredelenii sostoyaniya parodonta [Efficiency of some clinical indexes in determination of parodontium condition]. Stomatologiya, 2, 20–28. [in Russian].

Holovko, N. V., & Babenko, A D. (2010) Otsinka stanu hihiieny porozhnyny rota i tkanyn parodonta v patsiientiv iz khronichnym hinhivitom na tli likuvannia neznimnoho tekhnikoiu [Evaluation of state of oral hygiene and parodontal tissues in patients with chronic ginigivitis at the background of treatment of fixed equipment]. Ukrainskyi stomatolohichnyi almanakh, 1, 8–10. [in Ukrainian].

Kozlov, V. A., Artyushenko, N. K., 7 Shalak, O. V. (2000). Ul'trazvukovaya dopplerografiya v ocenke sostoyaniya gemodinamiki v tkanyakh shei, lica i polosti rta v norme i pri nekotorykh patologicheskikh sostoyaniyakh [Ultrasonic dopplerography in estimation of state of hemodynamics in tissues of the neck, face and oral casvty in the norm and under some pathological conditions]. Patologicheskaya fiziologiya i e´ksperimental'naya terapiya, 6, 32–36. [in Russian].

Shuntikova, E. V., Aleksandrov, P. N., & Kozhevnikova, L. A. (2011). Izmeneniye mikrocirkulyatornogo rusla desny v norme i pri parodontite [Change of microvascular blood stream of gum in norm and with parodontitis]. Klinicheskaya implantologiya i stomatologiya, 3, 54–58. [in Russian].

Matisova, E. V., & Kramar, B. S. (2010). Mikroe´kologiya polosti rta i yeyo rol' v razvitii stomatologicheskikh zabolevanij [Oral microecology and its role in development of dental diseases]. Volgograd: izd-vo Volg. GMU. [in Russian].

Redinova, T. L., Ivanova, L. A., Martiusheva, O. V., Cherednikova, L. A., & Cherednikova, A. B. (2009) Microbiological and clinical characteristics of oral cavity disbiotic status. Stomatologiya, 88(6), 12–18. [in English].

Zelenova, E. G., Zaslavskaya, M. I., & Salina, E. V. (2004). Mikroflora polosti rta: norma i patologiya [Microflora of oral cavity: norm and pathology]. Nignij Novgorod. [in Russian].

Downloads

How to Cite

1.
Romanova YG, Kravchenko LS, Gerasymova IV, Davidenko ON, Koval SN. Results of clinical approbation of new local treatment method in the complex therapy of inflammatory parodontium diseases. Zaporozhye Medical Journal [Internet]. 2017Jul.3 [cited 2024Nov.14];(4). Available from: http://zmj.zsmu.edu.ua/article/view/104920

Issue

No. 4 (2017)

Section

Original research

License

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.  Лицензия Creative Commons
    2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
    3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)