Anthropometric studies of patients with nonalcoholic fatty liver disease
DOI:
https://doi.org/10.14739/2310-1210.2017.5.110169Keywords:
non-alcoholic fatty liver disease, diagnosis, anthropometry, discriminant analysisAbstract
There is a great interest in non-invasive markers of non-alcoholic fatty liver disease (NAFLD) in clinical practice because liver biopsy is performed only for certain indications.
Aim. Improvement of prognostication diagnosis of NAFLD in men and women of the first mature age by defining a set of anthropometric parameters of patients, who are under examination for various reasons.
Materials and methods. We examined 112 patients of the first mature age with NAFLD. The diagnosis was based on a comprehensive analysis of complaint data physical examination, laboratory and instrumental studies. The control group included 225 healthy urban men and women of similar age taken from the bank of the materials from research center of National Pirogov Memorial Medical University, Vinnytsya. All anthropometric survey conducted by the scheme V. Bunak. We used the method of stepwise discriminant analysis to develop risk prediction NAFLD depending on the characteristics of the body structure.
Results. Discriminant replaceable between healthy and sick men and women were the following anthropometric indicators: body mass index, waist circumference, hip circumference, waist circumference to hip circumference, chest circumference as an exhalation, height of supragastral point, difference between the height of the supragastral point and the height of the pubic Points, determination of muscle mass by Matejko. By using discriminant analysis was established discriminant function for predicting the presence NAFLD of individuals who investigated for checkups.
Conclusion. The new NAFLD anthropometric diagnostic criteria for men and women of the first mature age of Podolskyi region could help to suspect the desease even at the first examination of the patient. Gender differences in anthropometric criteria NAFLD patients were identified. Anthropometric criteria can be used to diagnose NAFLD during preventive examinations, family doctor visits and outpatient examination of people.
References
Rinella, M. E. (2015) Nonalcoholic fatty liver disease: a systematic review. JAMA, 313(22), 2263–2273. doi: 10.1001/jama.2015.5370.
Sayiner, M., Koenig, A., Henry, L., & Younossi, Z. M. (2016) Epidemiology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis in the United States and the Rest of the World. Clinics in Liver Disease, 20(2), 205–214. doi: 10.1016/j.cld.2015.10.001.
Macaluso, F. S., Maida, M., & Petta, S. (2015) Genetic background in nonalcoholic fatty liver disease: A comprehensive review. World J Gastroenterol, 21(39), 11088–11111. doi: 10.3748/wjg.v21.i39.11088.
Kuhle, S., Maguire, B., Ata, N., & Hamilton, D. (2015) Percentile Curves for Anthropometric Measures for Canadian Children and Youth. PLoS One, 10(7), e0132891. doi: 10.1371/journal.pone.0132891.
Hardy, D. S., Stallings, D. T., Garvin, J.T., Xu, H., & Racette, S. B. (2017) Best anthropometric discriminators of incident type 2 diabetes among white and black adults: A longitudinal ARIC study. PLoS One, 12(1), e0168282. doi: 10.1371/journal.pone.0168282.
Katzmarzyk, P. T., Greenway, F. L., Heymsfield, S. B., & Bouchard, C. (2013) Clinical utility and reproducibility of visceral adipose tissue measurements derived from dual-energy X-ray absorptiometry in White and African American adults. Obesity (Silver Spring), 21(11), 2221–2224. doi: 10.1002/oby.20519.
Kravchun, N. A., Zemlianitsyna, O. V., & Dorosh, O. V. (2012) Kliniko-antropometrychna kharakterystyka khvorykh na tsukrovyi diabet 2 typu iz nealkoholnoiu zhyrovoiu khvoroboiu pechinky [Clinical and anthropometric characteristics of patients with type 2 diabetes mellitus and non-alcoholic fatty liver disease]. Problemy endokrynnoi patolohii, 1, 33–37. [in Ukrainian].
Park, S. K., Ryoo, J.-H., Choi, J.-M., Seo, M. W., & Park, Ch. M. (2016) The Risk of Abdominal Obesity according to the Degree of Non-Alcoholic Fatty Liver Disease in Korean Men. J. Korean Med. Sci., 31(3), 410–416. doi: 10.3346/jkms.2016.31.3.410.
Zheng, R.-D., Chen, Z.-R., Chen, J.-N., Lu, Ya.-H., & Chen, J. (2012) Role of Body Mass Index, Waist-to-Height and Waist-to-Hip Ratio in Prediction of Nonalcoholic Fatty Liver Disease. Gastroenterol Res Pract, 2012. doi: 10.1155/2012/362147.
Motamed, N., Rabiee, B., Hemasi, G. R., Ajdarkosh, H., Khonsari, M. R., Maadi, M., et al. (2016) Body Roundness Index and Waist-to-Height Ratio are Strongly Associated With Non-Alcoholic Fatty Liver Disease: A Population-Based Study. Hepat Mon, 16(9), e39575. doi: 10.5812/hepatmon.39575.
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