Regional monitoring of the urinary tract infections etiological spectrum pathogens in the child population in Chernivtsi region: dynamic changes, age, gender, administrative and territorial characteristics

Authors

  • V. V. Bezruk Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine,
  • T. О. Bezruk Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine,
  • O. R. Babiy Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine,
  • S. O. Sokolnyk Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine,
  • M. I. Sheremet Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine,
  • V. V. Maksymyuk Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine,
  • O. I. Godovanets Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine,
  • O. S. Godovanets Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine,
  • A. I. Kovtun Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine,

DOI:

https://doi.org/10.14739/2310-1210.2017.5.110222

Keywords:

urinary tract infections, children

Abstract

Microbiological monitoring of the uropathogens is an effective «tool» for urinary tract infectious and inflammatory diseases treatment quality improvement.

The aim of the article is to determine the range of the urinary tract infectious-inflammatory diseases etiological spectrum groups of pathogens in the child population in Chernivtsi region.

Materials and methods. The etiologic spectrum of uropathogens identified in the urine samples of 657 patients who were provided with a specialized medical care in the Nephrology Department of the «Municipal Children’s Clinical Hospital», Chernivtsi (2014–2015) was analyzed in order to dynamically control the possible changes of the «urinary tract infections» (UTI) regional etiological structure and antibiotic resistance of pathogens; identification of age and gender differences of urine microbial diversity in the child population in Chernivtsi region (2014–2015) compared with the monitoring data for the 2009–2013 period.

Results. A significant difference has been found in the etiological structure of the urine microbial diversity in children with infectious and inflammatory diseases of the urinary tract (Gram-positive cocci – p < 0.05; Enterobacteria – p < 0.01; resident microflora – p < 0.01) in comparison with uropathogens extracted in children with urinary tract noninfectious diseases. Administrative and territorial differences have been registered in etiological structure of the urine microbial diversity in children living in the urban areas (p < 0.01) from their peers living in the rural areas.

Conclusions. The regional monitoring data showed changes of the urine resident microflora (p < 0.01) without significant changes of etiological spectrum of the UTI pathogens in examined children (0–18 years old) with urinary tract infectious and inflammatory diseases during 2009–2015 in Chernivtsi region. At the same time it as a matter of concern a significant increase in the proportion of «negative results» (no growth) in the urine bacteriological analysis (p < 0.01), which might indirectly indicate the «uncontrolled» use of antibiotics among children in the region.

References

Bezruk, V., Blinder, O., Bezruk, T., Blinder, O., & Yurniuk, S. (2014) Etiological structure of the urinary system infections, its dynamic, dependence on patients sex and relation with resident urine microflora among inhabitants of Chernivtsi region and town of Chernivtsi. Canadian Scientific Journal, 2, 25–35.

Bezruk, V. V. (2015). Infektsii sechovoii systemy u ditei: etiolohichna struktura, vikovi ta henderni osoblyvosti [Urinary tract infection in children: etiological structure, age and gender characteristics]. Zdorov'e rebenka, 7, 113–117. [in Ukrainian].

Bezruk, V. V., Blinder, O. V., Bezruk, T. О., Blinder, O. O., & Deyneka, S. E. (2015). Antybiotykorezystentnist osnovnykh hrup zbudnykiv infektsii sechovoi systemy [Antimicrobial resistance in pathogens causing urinary tract infections]. Ukrainskyi zhurnal nefrolohii ta dializu, 4, 9–15. [in Ukrainian].

Grabe, M., Bjerklund-Johansen, T. E., Botto, H., Çek, M., Naber, K. G., Pickard, R. S., et al. (2013) Guidelines on urological infections. Eur Assoc Urology.

Stein, R., Dogan, H. S., Hoebeke, P., Kočvara, R., Nijman, R. J., Radmayr, C., et al. (2015) Urinary Tract Infections in Children: EAU/ESPU Guidelines. European urology, 67(3), 546–558. doi: 10.1016/j.eururo.2014.11.007.

Rosner, B. (2010) Fundamentals of Biostatistics. Duxbury Press.

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How to Cite

1.
Bezruk VV, Bezruk TО, Babiy OR, Sokolnyk SO, Sheremet MI, Maksymyuk VV, Godovanets OI, Godovanets OS, Kovtun AI. Regional monitoring of the urinary tract infections etiological spectrum pathogens in the child population in Chernivtsi region: dynamic changes, age, gender, administrative and territorial characteristics. Zaporozhye medical journal [Internet]. 2017Oct.17 [cited 2024Apr.19];(5). Available from: http://zmj.zsmu.edu.ua/article/view/110222

Issue

No. 5 (2017)

Section

Original research

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