Anatomical optical, biomechanical and morphometric parameters of the eye in children with acquired myopia and syndrome of undifferentiated connective tissue dysplasia

Authors

  • T. Ye. Tsybulska Zaporizhzhia State Medical University, Ukraine,
  • N. G. Zavgorodnia Zaporizhzhia State Medical University, Ukraine,
  • O. M. Ivakhnenko Zaporizhzhia State Medical University, Ukraine,
  • O. Ye. Pashkova Zaporizhzhia State Medical University, Ukraine,

DOI:

https://doi.org/10.14739/2310-1210.2018.3.130514

Keywords:

myopia, children, connective tissue diseases

Abstract

Aim of the research – to make a comprehensive assessment of anatomical, optical, biomechanical and morphometric parameters of the eye in children with acquired myopia and syndrome of undifferentiated connective tissue dysplasia.

Materials and methods. We examined patients of 2 groups: the I group – 44 children (88 eyes) with myopia of mild degree and phenotypic manifestations of connective tissue dysplasia, the II group – 40 patients (80 eyes) with myopia and without signs of connective tissue dysplasia. We measured the following parameters: corneal refractive power, corneal diameter and radius, thickness of the cornea, anterior chamber depth, lens thickness, sagittal length of the vitreous body, axial length of the eye, corneal hysteresis, peripapillary retinal nerve fiber layer thickness.

Results. We revealed significant differences in the anatomical, optical and biomechanical parameters of the visual analyzer in children with myopia of mild degree on the background of the UCTD, in contrast to children with myopia and without connective tissue dysplasia, which consisted in corneal refractive power reduction to an average of 41.25 [40.62; 41.75] D, increase in the corneal radius to an average of 8.13 [7.97; 8.28] mm, the corneal diameter to an average of 12.5 [12.1; 12.7] mm, the anterior chamber depth to an average of 3.8 [3.4; 4.0] mm, the sagittal length of the vitreous body to an average of 17.6 [17.3; 18.0] mm, the axial length of eye to an average of 24.9 [24.4; 25.4] mm, decrease in corneal hysteresis to an average of 11.2 [10.6; 11.7] mm Hg. Peripapillary retinal nerve fiber layer thickness was reduced to an average of 87 [85; 93] μm.

Conclusions. The obtained data can be useful in a comprehensive assessment of ophthalmic manifestations of undifferentiated connective tissue dysplasia syndrome, in myopic process development prediction and in individual treatment tactics determination.

References

Budnik, T. V. (2014) Rezul'taty sopostavleniya fenotipicheskikh i klinicheskikh priznakov nedifferencirovannoj displazii soedinitel'noj tkani, mikroe'lementnoj obespechennosti i oftal'mologicheskikh dannykh u detej s progressiruyuschej miopiej [A comparison of phenotypic and clinical signs of connective tissue dysplasia, micronutrient sufficiency and ophthalmic data in children with progressive myopia]. Perinatologiya i peditriya, 2, 41–45. [in Russian].

Iomdina, E. N., Tarutta, E. P., Markosyan, G. A., Aksenova, Yu. M., Kruzhkova, G. V., Ivashchenko, Zh. N., et al. (2013) Biomekhanicheskie pokazateli korneoskleralnoj obolochki glaza i sostoyanie soedinitel'notkannoj sistemy u detej i podrostkov s razlichnymi formami progressiruyuschej miopii [Biomechanical characteristics of the corneoscleral tunic and the state of the connective tissue system in the children and adolescents presenting with various forms of progressive myopia]. Rossijskaya pediatricheskaya oftal'mologiya, 1, 18–23. [in Russian].

Kadurina, T. I., & Gorbunova, V. N. (2008) Displaziya soedinitel'noj tkani [Connective tissue dysplasia]. Saint Petersburg. [in Russian].

Lezhenko, G. O., Volosovec, O. P., Krivopustov, S. P., Prokhorov, E. V., Pashkova, O. E., & Podlyanova, O. I. (2006) Syndrom nedyferentsiiovanoi dysplazii spoluchnoi tkanyny u ditei ta pidlitkiv (poshyrenist, osoblyvosti diahnostyky ta likuvannia) [The syndrome of undifferentiated connective tissue dysplasia in children and adolescents (prevalence, features of diagnosis and treatment). Zaporizhzhia: Vydavnytstvo Zaporizkoho derzhavnoho medychnoho universitetu. [in Ukrainian].

Pasechnikova, N. V., Ryjkov, S. A., Naumenko, L. Yu., & Kryzhanovskaya, T. V. (2010) Sostoyanie i aktual'nye problemy profilaktiki slepoty i slabovideniya v Ukraine [Status and current problems of prevention of blindnesss and visionin Ukraine]. Proceedings of the 12th congress of ophthalmologists of Ukraine. (P. 303–304). Odessa. [in Russian].

Seleznev, A. V., & Nasu, H. (2012) Dinamika miopicheskoj bolezni u lic s sindromom displazii soedinitel'noj tkani [Dynamics of myopia in individuals with syndrome of connective tissue dysplasia]. Oftal'mokhirurgiya, 4, 73–75. [in Russian].

Cibul'skaya, T. E., Zavgorodnyaya, N. G. & Pashkova, E. E. (2017) Ocenka fenotipicheskikh markerov sindroma nedifferencirovannoj displazii soedinitel'noj tkani u detej s priobretennoj miopiej [Evaluation of phenotypic markers of the syndrome of undifferentiated connective tissue dysplasia in children with acquired myopia]. Oftal'mologicheskij zhurnal, 2, 12–17. [in Russian].

Shabalov, N. P. (2012) Detskie bolezni [Childhood diseases]. Saint Petersburg. [in Russian].

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How to Cite

1.
Tsybulska TY, Zavgorodnia NG, Ivakhnenko OM, Pashkova OY. Anatomical optical, biomechanical and morphometric parameters of the eye in children with acquired myopia and syndrome of undifferentiated connective tissue dysplasia. Zaporozhye Medical Journal [Internet]. 2018May30 [cited 2024Nov.22];(3). Available from: http://zmj.zsmu.edu.ua/article/view/130514

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