Evaluation of Intracerebral Hemorrhage Functional Outcome Score informativeness for identification of short-term vital outcome in patients with spontaneous supratentorial intracerebral haemorrhage

Authors

  • A. A. Kuznietsov Zaporizhzhіa State Medical University, Ukraine,

DOI:

https://doi.org/10.14739/2310-1210.2018.6.146536

Keywords:

cerebral hemorrhage, X-Ray tomography, mortality, prognosis

Abstract

The main purpose of the study was to conduct the informative value of Intracerebral Hemorrhage Functional Outcome Score (ICH-FOS) assessment for the determination of a short-term vital prognosis in patients with spontaneous supratentorial intracerebral hemorrhage (SSICH).

Materials and methods. A prospective, cohort study was conducted among 191 patients (117 men and 74 women, the mean age was 65.1 ± 0.8 years) with SSICH treated in a conservative manner. This study included clinical assessment (National Institute of Health Stroke Scale, Glasgow Coma Scale), neuroimaging and biochemistry examination. The ICH-FOS was used in order to conduct a complex assessment of the patients’ state severity on admission. The functional outcome of the SSICH acute period was assessed on the 21st day of the disease in accordance with the modified Rankin Scale.

Results. Lethal outcome was noted in 22 patients (11.5 %). The patients with the lethal outcome during the acute period had a higher value of the ICH-FOS (8 (7–10) versus 4 (3–6), P < 0.0001) in the onset of SSICH. Based on a ROC-analysis it was determined that the ICH-FOS >6 is the predictor of the lethal outcome in the acute period of SSICH (Se = 77.3 %; Sp = 81.1 %; AUC ± SE (95 % CI) = 0.86 ± 0.04 (0.80–0.91), P < 0.0001). In the group of patients with the ICH-FOS value >6 (n = 49) lethal outcome was noted in 34.7 % of cases, whereas in the group of patients with the ICH-FOS value ≤6 (n = 142) it was noted only in 3.5 % of cases.

Conclusions. The Intracerebral Hemorrhage Functional Outcome Sсore is a highly informative tool for the determination of a short-term vital prognosis of SSICH acute period outcome. The ICH-FOS >6 is associated with a 9.9-fold increased risk of lethal outcome (RR 95 % CI 3.8–25.3, P < 0.0001).

 

References

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1.
Kuznietsov AA. Evaluation of Intracerebral Hemorrhage Functional Outcome Score informativeness for identification of short-term vital outcome in patients with spontaneous supratentorial intracerebral haemorrhage. Zaporozhye Medical Journal [Internet]. 2019Feb.1 [cited 2024Nov.6];(6). Available from: http://zmj.zsmu.edu.ua/article/view/146536

Issue

No. 6 (2018)

Section

Original research

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