Features of etiology, pathogenesis, treatment and prophylaxis of periodontal diseases in pregnant women in the context of iron deficiency anemia (review of the literature)

Authors

  • O. H. Boichuk-Tovsta Ivano-Frankivsk National Medical University, Ukraine,
  • O. H. Boichuk Ivano-Frankivsk National Medical University, Ukraine,

DOI:

https://doi.org/10.14739/2310-1210.2019.1.155870

Keywords:

pregnant women, periodontal diseases, iron deficiency anemia

Abstract

An important task of modern dentistry is the study of dental morbidity in pregnant women with somatic pathology. This is due to many factors, including a significant prevalence of periodontal diseases among the population, infection impact on the body of the pregnant woman and the fetus, an increase in the frequency of somatic diseases in pregnant women.

The aim of the retrospective literary research was to study modern scientific trends regarding the peculiarities of etiology, pathogenesis, treatment and prophylaxis of periodontal diseases in pregnant women with iron deficiency anemia.

The collection of scientific publications (30 sources), including 19 domestic and 11 foreign professional sources, has been analyzed on the current issue of modern dentistry: periodontal diseases in pregnant women with iron deficiency anemia. The aspects of high prevalence of periodontal diseases among this contingent of patients, their polyethiologic origin, complex mechanism of development, peculiarities of treatment and prevention have been considered. According to the authors' researches, it was found that catarrhal gingivitis is the most common clinical form of the inflammatory process in the 1st trimester, gingivitis of pregnant women develops as a catarrhal or hypertrophic inflammation, rarely - ulcerous-necrotic gingival lesion in the 2nd trimester. The clinical picture of hypertrophic gingivitis in pregnant women is to be seen in its most clinical manifestation in the 3rd trimester and in the immediate prenatal period. Taking into account the fact that to date, in the majority of women, the actual consumption of macro- and micronutrients and vitamins with food is much lower than the level that provides a favorable course of pregnancy and lactation, the use of vitamin-mineral complexes are obligatory in pregnant women with periodontal disease and concomitant iron deficiency anemia. At the initial stages of generalized periodontitis, vitamin therapy is most effective. Today, foreign authors refer to the concept of micronutrient programming of the future baby's development during pregnancy, which is the applicability of multivitamin complexes. The main task of dentists and obstetrician-gynecologists is to create a conscious awareness of the importance of timely dental care in pregnant women by forming a positive motivation among expecting mothers to seek dental care. From these data, the optimal periods of dental examinations and differential approach to medical preventive measures can be determined.

References

Amonov, I. I. (2014). Mikroe'lementoz i anemiya u beremennukh v ochage yodnogo deficyta [Microelementosis and anemia in pregnant women in the focus of iodine deficiency]. Voprosy pitania, 1, 41–44. [in Russian].

Antonenko, M., Sidelnikova, L., & Budjakivskja, O. (2013) Pryntsypy profilaktyky zakhvoriuvan parodontu u vahitnykh [Principles of preventive maintenance of periodontal diseases at pregnant women]. Sovremennaya stomatologiya, 4, 35–37. [in Ukrainian].

Kuzmina, V., Yakubova, I., & Buchynska, T. (2015). Stomatolohichnyi status vahitnykh zhinok zalezhno vid osoblyvostei perebihu vahitnosti [Dental status of pregnant women depending on the characteristics of the process of pregnancy]. Sovremennaya stomatologiya, 3, 51–54. [in Ukrainian].

Borysenko, A., & Volovik, I. (2016). Sostoyanie stomatologicheskogo statusa u lic molodogo vozrasta v zavisimosti ot nalichiya zabolevanij parodonta [State of stomatological status in young adults depending on the presence of periodontal diseases]. Sovremennaya stomatologiya, 1, 28–34. [in Russian].

Bakhmudov, M. B., Bakhmudov, B. R., & Alieva, Z. B. (2008). Nuzhdaemost' beremennukh v sanacii polosti rta i opyt yeyo organizacii v usloviyakh zhenskoj konsul'tacii [Need oral cavity sanation of pregnants and experience in its organization in the structure of consulting-room for expectant mothers]. Stomatologiya, 87(4), 64–68. [in Russian].

Dimitrova, A., Dikova, I., & Mylkovsky, K. (2017). Dinamika rasprostranennosti i osobennosti struktury zabolevaemosti parodonta u lic molodogo vozrasta [Dynamics of prevalence and features of the structure of periodontal diseases in young people]. Sovremennaya stomatologiya, 4, 32–35. [in Russian].

Veropotvelyan, P. N., Veropotvelyan, N. P., Pivneva, N. V., Osadchuk, E. G., & Pivnev, M. S. (2015). Zhelezodeficitnaya anemiya beremennykh: sovremennyj vzghlyad na e'tiopatogenez i terapiyu [Iron deficiency anemia in pregnancy: a modern view on etiopathogenesis and therapy]. Medicinskie aspekty zdorov'ya zhenshchiny, 6, 32–38. [in Russian].

Kogut, Yu. (2015). Zhelezodeficitnaya anemiya v akusherstve i operativnoj ginekologii: sovremennye podkhody k profilaktike oslozhnenij i vospolnenij deficita zheleza [Iron deficiency anemia in obstetrics and operative gynecology: modern approaches to the prevention of complications and the replacement of iron deficiency]. Zdorov'ye zhenshchiny, 10, 24–27. [in Russian].

Malkoch, A. V., Anastasevich, L. A., & Filatova, N. N. (2013) Zhelezodeficitnye sostoyaniya i zhelezodeficitnaya anemiya u zhenshchin detorodnogo vozrasta [Iron-deficiency states and iron-deficiency anemia in women of child-bearing age]. Reproduktivnaya e'ndokrinologiya, 5, 22–27. [in Russian].

Nikolaeva, A. V., & Nagornaya, V. F. (2016). Zabolevaniya parodonta u zhenshchin s narusheniem sekrecii e'strogenov [Periodontal diseases in women with a violation of estrogen secretion]. Visnyk naukovykh doslidzhen, 2, 73–75. [in Russian]. doi: 10.11603/2415-8798.2016.2.6705.

Ostrovska, L. Y. (2016). Zakhvoriuvanist tkanyn parodonta vahitnykh, mekhanizmy vynyknennia ta rozvytku (ohliad literatury) [Morbidity of periodontal tissue of pregnant women and the mechanism of its occurrence and development (review of the references)]. Bukovynskyi medychnyi visnyk, 20(1), 215–219. [in Ukrainian].

Politun, A., & Yakovets, O. (2015). Klinichna otsinka stanu tkanyn parodontu u vahitnykh [Clinical assessment of periodontal tissue in pregnant women. Sovremennaya stomatologiya, 4, 42–44. [in Ukrainian].

Sokolova, N. (2013). Profiylaktyka I lechenie zabolevanij parodonta [Prevention and treatment of periodontal diseases]. Sovremennaya farmaciya, 1, 78–81. [in Russian].

Tyutyunnik, V. L., Balushkina, A. A., & Kan, N. E. (2013). Vozmozhnosti korrekcii zhelezodeficitnoj anemii srednej y tyazholoj stepeni u rodil'nic [Correction of severe and moderate iron deficiency anemia in postpartum women]. Voprosy ginekologii, akusherstva i perinatologii, 12(1), 16–20. [in Russian].

Borysenko, A. V., Bychkova, N. H., & Timokhina, T. O. (2013). Riven tsytokiniv u vahitnykh zhinok iz zalizodefitsytnoiu anemiieiu ta heneralizovanym parodontytom [The level of cytokines in pregnant women with iron deficiency anemia and generalized periodontiti]. Sovremennaya stomatologiya, 4, 28–32. [in Ukrainian].

Borysenko, A. V. & Timokhina, T. O. (2013) Kharakteristika mikroflory porozhnyny rota u zhinok reproduktivnogo viku iz zalizodeficytnoyu anemieyu [The Characteristic of Microflora of an Oral Cavity at Women of Reproductive age with an Asidoretic (iron-deficiency) Anemia]. Novyny stomatologii, 3, 48–51. [in Ukrainian].

Shekera, O. O. & Shekera, I. O. (2013). Pytannia profilaktyky ta likuvannia zakhvoriuvan parodonta u vahitnykh [Problems of prophylaxis and treatment of periodontal diseases in pregnant women]. Zdorovia suspilstva, 2(1), 49–51. [in Ukrainian].

Korovina, N. A., Podzolkova, N. M., & Zakharova, I. N. (2014) Vliyanie vitaminov i mikroe'lementov na sostoyanie zdorov'ya beremennoj zhenshchiny i ploda [Influence of vitamins and microelements on the state of health of a pregnant woman and fetus]. Lechashchij vrach, 12, 1–3. [in Russian].

Tofan, N. I. (2013). Gematologicheskie pokazateli kak kriterii e'ffektivnosti sanatorno-kurortnogo lecheniya beremennykh s anemiyami [Hematologic indices as criteria of efficiency of sanatorium-and-spa treatment of pregnant women with anemia]. Laboratornaya diagnostika, 4, 59–62. [in Russian].

Abati, S., Villa, A., Cetin, I., Dessole, S., Luglie, P. F., Strohmenger, L., et al. (2016). Lack of association between maternal periodontal status and adverse pregnancy outcomes: a multicentric epidemiologic study. J Matern Fetal Neonatal Med, 26(4). 369–372. doi: 10.3109/14767058.2012.733776.

Blanc, V., O’Valle, F., Pozo, E., Puertas, A., Leon, R., & Mesa, F. (2015). Oral bacteria in placental tissues: increased molecular detection in pregnant periodontitis patients. Oral Diseases., 21(7), 905–907. doi: 10.1111/odi.12364.

Ide, M., & Papapanou, P. N. (2013). Epidemiology of association between maternal periodontal disease and adverse pregnancy outcomes-systematic review. J Periodontol, 84(4 Suppl), S181–94. doi: 10.1902/jop.2013.134009.

Kayar, N. A., Alptekin, N. O., & Haliloglu, S. (2015). Interleukin-1 receptor antagonist levels in gingival crevicular fluid and serum in nonsmoking women with preterm low birth weight and intrauterine growth retardation. Eur J Dent., 9(1), 109–16. doi: 10.4103/1305-7456.149655.

Mesa, F., Pozo, E., Blanc, V., Puertas, A., Bravo, M., & O’Valle, F. (2013). Are periodontal bacterial profiles and placental inflammatory infiltrate in pregnancy related to birth outcomes? J Periodontol, 84(9), 1327–1329. doi: 10.1902/jop.2012.120462.

Pozo, E., Mesa, F., Ikram, M. H., Puertas, A., Torrecillas-Martinez, L., Ortega-Oller, I., et al. (2016). Preterm birth and/or low birth weight are associated with periodontal disease and the increased placental immunohistochemical expression of inflammatory markers. Histol Histopathol, 31(2), 231–234. doi: 10.14670/HH-11-671.

Soroye, M., Ayanbadejo, P., Savage, K., & Oluwole, A. (2015). Association between periodontal disease and pregnancy outcomes. Odontostomatol Trop., 38(152), 5–16.

Takeuchi, N., Ekuni, D., Irie, K., Furuta, M., Tomofuji, T., Morita, M., & Watanabe, T. (2013). Relationship between periodontal inflammation and fetal growth in pregnant women: a cross-sectional study. Arch Gynecol Obstet., 287(5), 951–957. doi: 10.1007/s00404-012-2660-4.

Zi, M. Y., Longo, P. L., Bueno-Silva, B., & Mayer, M P. (2014). Mechanisms involved in the association between periodontitis and complications in pregnancy. Front Public Health., 2, 290. doi: 10.3389/fpubh.2014.00290.

Chung, L. H., Gregorich, S. E., Armitage, G. C., Gonzalez-Vargas, J., & Adams, S. H. (2014). Sociodemographic disparities and behavioral factors in clinical oral health status during pregnancy. Community Dent Oral Epidemiol., 42(2), 151–9. doi: 10.1111/cdoe.12075.

Chakraborty, S., Tewari, S., Sharma, R. K., Narula, S. C., Ghalaut, P. S., & Ghalaut, V. (2014). Impact of iron deficiency anemia on chronic periodontitis and superoxide dismutase activity: a cross-sectional study. Periodontal Implant Sci., 44(2), 57–64. doi: 10.5051/jpis.2014.44.2.57

How to Cite

1.
Boichuk-Tovsta OH, Boichuk OH. Features of etiology, pathogenesis, treatment and prophylaxis of periodontal diseases in pregnant women in the context of iron deficiency anemia (review of the literature). Zaporozhye medical journal [Internet]. 2019Feb.8 [cited 2024Feb.24];(1). Available from: http://zmj.zsmu.edu.ua/article/view/155870

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Section

Review