Use of bacterial drugs for allergic diseases treatment: pros and cons


  • A. V. Chornomydz Ivan Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine,
  • O. R. Boiarchuk Ivan Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine,
  • O. M. Oleschuk Ivan Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine,
  • I. B. Chornomydz Ivan Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine,



hypersensitivity, allergic diseases, microbiota, probiotics, prebiotics, hygiene theory



The purpose of this work is to establish the main arguments for expediency and inexpediency of bacterial drugs use in allergic pathology treatment based on the literary sources analysis.

In recent years, the most popular topic of scientific discussion is the bacterial drugs use for various diseases treatment, including allergic pathology. Numerous studies have confirmed the important role of microbiota in the immune system development and function as well as in allergic diseases occurrence. It is quite predictable that bacterial drugs use in this case is pathogenetically substantiated and should be effective. Currently, a large number of publications demonstrate the efficient use of bacterial agents in the treatment and prevention of allergic diseases in experimental conditions. However, despite promising experimental studies, the reliable clinical evidence of the probiotics efficacy in allergic diseases treatment does not exist. Few scientific publications evidencing the moderate probiotics efficacy in atopic dermatitis treatment have not been confirmed in large-scale meta-analyses. Some reports inform about an adverse effect of bacterial drugs on the course of allergic diseases. Therefore, these medications can not be used today as drugs for the pathogenetic treatment of allergic diseases, but have found a use as additional medicinal agents or nutritional supplements.

Conclusions. Taking into account the results of many scientific papers, we can confirm the relationship between allergic diseases and the microbiota state. Even so, effective influence of probiotics on an allergy course has not been proved. An impact on risk factors would be more appropriate, in particular, breastfeeding promotion, lifestyle modification and rational nutrition. This approach may be simple and effective.



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How to Cite

Chornomydz, A. V., Boiarchuk, O. R., Oleschuk, O. M., & Chornomydz, I. B. (2020). Use of bacterial drugs for allergic diseases treatment: pros and cons. Zaporozhye Medical Journal, 22(1).