Fatal cerebral and cardiac infarction due to embolism of a mobile thrombus from aorta sinotubular junction atheroma in a 40-year-old female

Authors

DOI:

https://doi.org/10.14739/2310-1210.2020.4.208414

Keywords:

sinotubular junction atheroma, mobile thrombus, cerebral infarction, myocardial infarction, young age

Abstract

 

Strokes in young adults present a challenging problem in terms of care and social impact. Most of cases in this cohort are classified as strokes of uncertain etiology. Application of multimodality diagnostic approach could help in the estimation of risk factors and underlying mechanisms. Simultaneous acute cardio-cerebral infarction is a rare manifestation, especially in young individuals. Large artery atherosclerosis should be excluded as a potential cause. Transesophageal echocardiography plays an important role in the diagnostic algorithm.

The current article presents a clinical case of a fatal acute cardio-cerebral infarction in a 40-year old female without previous cardiovascular diseases and negative family history. Transesophageal echocardiography identified a large mobile thrombus at the sinotubular junction of ascending aorta. Transthoracic echocardiography revealed regional akinesia of the inferior wall, despite normal electrocardiogram. The autopsy findings confirmed co-occurrence of thromboembolic stroke in the right middle cerebral artery area and left ventricular inferior myocardial infarction due to thrombosis of the right coronary artery. This case documents an exceedingly rare phenomenon in this cohort of a cardio-cerebral thromboembolism due to single atherosclerotic plaque destabilization.

References

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How to Cite

1.
Kavalerchyk V, Kolesnyk M, Woehlke M, Staudt A, Hagendorff A. Fatal cerebral and cardiac infarction due to embolism of a mobile thrombus from aorta sinotubular junction atheroma in a 40-year-old female. Zaporozhye Medical Journal [Internet]. 2020Jul.22 [cited 2024Dec.23];22(4). Available from: http://zmj.zsmu.edu.ua/article/view/208414

Issue

Vol. 22 No. 4 (2020)

Section

Case Reports

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