Pregnancy and breast cancer: optimal patient management tactics (a literature review)

Authors

  • O. P. Kolesnik Zaporizhzhia State Medical University, Oncolife LLC, Ukraine, Ukraine
  • A. I. Shevchenko Zaporizhzhia State Medical University, Ukraine, Ukraine
  • A. V. Kadzhoian Zaporizhzhia State Medical University; Oncolife LLC, Ukraine, Ukraine
  • O. M. Levyk Zaporizhzhia State Medical University, Oncolife LLC, Ukraine, Ukraine
  • D. Ye. Chernyavskyi Zaporizhzhia State Medical University, Oncolife LLC, Ukraine, Ukraine
  • V. O. Kuzmenko Zaporizhzhia State Medical University, Oncolife LLC, Ukraine, Ukraine
  • L. S. Lytvynenko Zaporizhzhia State Medical University, Ukraine, Ukraine

DOI:

https://doi.org/10.14739/2310-1210.2021.4.211358

Keywords:

breast cancer, pregnancy, cancer, chemotherapy, radiation

Abstract

Breast cancer is one of the most widespread malignant neoplasm in Ukraine (20.6 % of all malignant neoplasms). The usual incidence of breast cancer (BC) in women, as of 2019, is 70.3 cases per 100 thousand population. At the moment, BC during pregnancy is rare (only in 0.4 % of all BC cases in women aged 16 to 49 years), the decision on treatment remains difficult for a patient as well as an oncologists.

Despite the fact that the treatment of malignant breast disease is usually carried out in non-pregnant women, the problem of tactics for managing patients with different gestation lengths remains unresolved. Thus, the treatment of pregnant women with BC should be guided a multidisciplinary integrated approach to maximize the benefits and minimize the risk to both a mother and a fetus, including the optimal tactics of surgical treatment and chemotherapy. Therapeutic decisions should be based on the stage of disease, tumor morphology, gestational age at diagnosis, and possible pregnancy risks.

A promising way of addressing this problem is to conduct more studies to determine the most effective and safest treatment strategies for BC in pregnant women.

Author Biographies

O. P. Kolesnik, Zaporizhzhia State Medical University, Oncolife LLC, Ukraine

MD, PhD, DSc, Professor, Head of the Department of Oncology and Oncosurgery, oncologist, oncosurgeon

A. I. Shevchenko, Zaporizhzhia State Medical University, Ukraine

MD, PhD, DSc, Professor f the Department of Oncology and Oncosurgery

A. V. Kadzhoian, Zaporizhzhia State Medical University; Oncolife LLC, Ukraine

MD, PhD, Assistant of the Department of Oncology and Oncosurgery, Director of Oncolife LLC

O. M. Levyk, Zaporizhzhia State Medical University, Oncolife LLC, Ukraine

MD, PhD, Associate Professor of the Department of Oncology and Oncosurgery, oncologist

D. Ye. Chernyavskyi, Zaporizhzhia State Medical University, Oncolife LLC, Ukraine

MD, Senior Laboratory Assistant, oncologist

V. O. Kuzmenko, Zaporizhzhia State Medical University, Oncolife LLC, Ukraine

MD, Assistant of the Department of Oncology and Oncosurgery,  oncologist, oncosurgeon

L. S. Lytvynenko, Zaporizhzhia State Medical University, Ukraine

sixth-year student of the 1st Medical Faculty

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Published

2021-07-01

How to Cite

1.
Kolesnik OP, Shevchenko AI, Kadzhoian AV, Levyk OM, Chernyavskyi DY, Kuzmenko VO, Lytvynenko LS. Pregnancy and breast cancer: optimal patient management tactics (a literature review). Zaporozhye medical journal [Internet]. 2021Jul.1 [cited 2024Apr.20];23(4):599-604. Available from: http://zmj.zsmu.edu.ua/article/view/211358

Issue

Vol. 23 No. 4 (2021)

Section

Review

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