Results of the surgical treatment of diffuse pigmented villonodular synovitis (diffuse-type tenosynovial giant-cell tumor) of the knee

Authors

DOI:

https://doi.org/10.14739/2310-1210.2021.5.230164

Keywords:

pigmented villonodular synovitis, knee joint, tenosynovial giant cell tumor

Abstract

The aim. To develop a treatment algorithm with the aim of improving the treatment results of diffuse pigmented villonodular synovitis of the knee. To study and analyze the results of surgical treatment of diffuse pigmented villonodular synovitis of the knee.

Materials and methods. The study was based on the results of treatment of 48 patients with pathohistologically verified diagnosis of diffuse pigmented villonodular synovitis (tenosynovial giant cell tumor) of the knee undergoing treatment at the State Institution “Institute of Traumatology and Orthopedics of the National Academy of Medical Sciences of Ukraine” from 2010 to 2019.

Results. The best functional results can be achieved in patients with diffuse pigmented villonodular synovitis of the knee in stage I of the disease. Using the method of mathematical statistics to evaluate the results obtained, we see that scores obtained through the Lysholm Scoring Scale were statistically significantly different in stages before a surgery (P = 0.000782), 3 months (P = 0.00005) and 6 months after the surgery (P = 0.04); but over time, these differences diminished and became actually insignificant 12 months after the surgery (P = 0.89).

Conclusions. Applying our therapeutic algorithm for the treatment of patients with diffuse pigmented villonodular synovitis of the knee, the outcome of the Lysholm score was excellent in 22 % of patients, good – in 45 %, satisfactory – in 21 % and poor – in 12 % of patients.

Author Biographies

S. I. Herasymenko, SI «Institute of Traumatology and Orthopedics of the National Academy of Medical Sciences of Ukraine», Kyiv

MD, PhD, DSc, Professor, Head Doctor, Head of the Department of Joint Diseases in Adults

O. A. Kostogryz, SI “Institute of Traumatology and Orthopedics of the NAMS of Ukraine”, Kyiv

MD, PhD, DSc, Deputy Head Doctor for Surgical Care

Yu. O. Kostogryz, SI “Institute of Traumatology and Orthopedics of the NAMS of Ukraine”, Kyiv

MD, PhD, Junior Researcher of the Department of Joint Diseases in Adults

A. M. Babko, SI “Institute of Traumatology and Orthopedics of the NAMS of Ukraine”, Kyiv

MD, PhD, DSc, Senior Researcher of the Department of Joint Diseases in Adults

V. M. Mayko, CNE “Vinnytsia Regional Clinical Hospital named after M. I. Pyrohov of the Vinnytsia Regional Council”, Ukraine

MD, PhD, DSc, Associate Professor, Head of the Center for Orthopedics, Endoprosthesis and Reconstructive Traumatology

References

Murphey, M. D., Rhee, J. H., Lewis, R. B., Fanburg-Smith, J. C., Flemming, D. J., & Walker, E. A. (2008). Pigmented Villonodular Synovitis: Radiologic-Pathologic Correlation. RadioGraphics, 28(5), 1493-1518. https://doi.org/10.1148/rg.285085134

Simonetta R., Florio M., Familiari F., Gasparini G. & Rjsa M. A. (2017). All-Arthroscopic Treatment of Intra- and Extra-Articular Localized Villonodular Synovitis of Knee. Joints, 5(3), 184-187. https://doi.org/10.1055/s-0037-1605586

O'Connell, J. X. (2000). Pathology of the Synovium. American Journal of Clinical Pathology, 114(5), 773-784. https://doi.org/10.1309/LWW3-5XK0-FKG9-HDRK

Lin, J., Jacobson, J. A., Jamadar, D. A., & Ellis, J. H. (1999). Pigmented villonodular synovitis and related lesions: the spectrum of imaging findings. American Journal of Roentgenology, 172(1), 191-197. https://doi.org/10.2214/ajr.172.1.9888766

Bravo, S. M., Winalski, C. S., & Weissman, B. N. (1996). Pigmented Villonodular Synovitis. Radiologic Clinics of North America, 34(2), 311-326.

Rydholm, U. (1998). How I do it: Pigmented villonodular synovitis. Acta Orthopaedica Scandinavica, 69(2), 203-210. https://doi.org/10.3109/17453679809117632

Abdelwahab, I. F., Kenan, S., Steiner, G. C., & Abdul-Quader, M. (2002). True bursal pigmented villonodular synovitis. Skeletal Radiology, 31(6), 354-358. https://doi.org/10.1007/s00256-002-0491-2

Dines, J. S., DeBerardino, T. M., Wells, J. L., Dodson, C. C., Shindle, M., DiCarlo, E. F., & Warren, R. F. (2007). Long-term Follow-up of Surgically Treated Localized Pigmented Villonodular Synovitis of the Knee. Arthroscopy, 23(9), 930-937. https://doi.org/10.1016/j.arthro.2007.03.012

Sharma, V., & Cheng, E. Y. (2009). Outcomes after Excision of Pigmented Villonodular Synovitis of the Knee. Clinical Orthopaedics and Related Research, 467(11), 2852-2858. https://doi.org/10.1007/s11999-009-0922-7

Rauh, P. B., Bernard, J., & Craig, D. M. (2002). Pigmented villonodular synovitis of the knee: average five-year follow-up of arthroscopic treatment. Journal of the Southern Orthopaedic Association, 11(2), 88-92.

De Ponti, A., Sansone, V., & Malcherè, M. (2003). Result of arthroscopic treatment of pigmented villonodular synovitis of the knee. Arthroscopy, 19(6), 602-607. https://doi.org/10.1016/s0749-8063(03)00127-0

Blanco, C. E., Leon, H. O., & Guthrie, T. B. (2001). Combined partial arthroscopic synovectomy and radiation therapy for diffuse pigmented villonodular synovitis of the knee. Arthroscopy, 17(5), 527-531. https://doi.org/10.1053/jars.2001.24068

Shabat, S., Kollender, Y., Merimsky, O., Isakov, J., Flusser, G., Nyska, M., & Meller, I. (2002). The use of surgery and yttrium 90 in the management of extensive and diffuse pigmented villonodular synovitis of large joints. Rheumatology, 41(10), 1113-1118. https://doi.org/10.1093/rheumatology/41.10.1113

Lysholm, J., & Gillquist, J. (1982). Evaluation of knee ligament surgery results with special emphasis on use of a scoring scale. The American Journal of Sports Medicine, 10(3), 150-154. https://doi.org/10.1177/036354658201000306

Bentley, G., Kreutner, A., & Ferguson, A. B. (1975). Synovial regeneration and articular cartilage changes after synovectomy in normal and steroid-treated rabbits. The Journal of Bone and Joint Surgery. British volume, 57(4), 454-462.

van der Heijden, L., Piner, S. R., & van de Sande, M. A. (2016). Pigmented villonodular synovitis: a crowdsourcing study of two hundred and seventy two patients. International Orthopaedics, 40(12), 2459-2468. https://doi.org/10.1007/s00264-016-3208-1

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Published

2021-09-01

How to Cite

1.
Herasymenko SI, Kostogryz OA, Kostogryz YO, Babko AM, Mayko VM. Results of the surgical treatment of diffuse pigmented villonodular synovitis (diffuse-type tenosynovial giant-cell tumor) of the knee. Zaporozhye medical journal [Internet]. 2021Sep.1 [cited 2024Apr.25];23(5):656-63. Available from: http://zmj.zsmu.edu.ua/article/view/230164

Issue

Vol. 23 No. 5 (2021)

Section

Original research

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