Breathing exercises with PEEP: efficiency and duration for correcting the cardiovascular system functional state in older patients with COPD

Authors

DOI:

https://doi.org/10.14739/2310-1210.2021.6.231350

Keywords:

COPD, elderly, breathing exercises, PEEP, cardiovascular system

Abstract

The aim of the work is to find out the effectiveness and duration of the breathing exercises with PEEP action on the cardiovascular system state in older patients with COPD.

Materials and methods. A total of 35 patients with COPD aged 60–74 years were examined. All the patients were divided into two groups: the main group (18 people) who received breathing exercises with PEEP, and the control group (17 people) who received simulated exercises. The cardiovascular system state was assessed. The examinations were performed in the initial state (before training), immediately after, one month later, and three months after the training course.

Results. The cardiovascular system state improved as a result of breathing exercises with PEEP in older patients with COPD. At the same time, the duration of the breathing exercises with PEEP action was short; the effect of their use was not preserved in a month. Relationships between shifts in SpO2 and cardiac output, as well as between shifts in SpO2 and peripheral vascular resistance immediately after the use of breathing exercises with PEEP in older patients with COPD have been established. A more significant and prolonged effect of breathing exercises with PEEP on the cardiovascular system functional state was observed in older COPD patients with more severe symptoms of the disease.

Conclusions. The increase in cardiovascular performance was influenced by breathing exercises with PEEP in older COPD patients due to the improved lung oxygenation capacity. The effect of breathing exercises with PEEP remained within a month after the training course and was more stable and longer in patients with severe clinical symptoms. Older COPD patients are advised to repeat the courses of breathing exercises with PEEP every month.

Author Biographies

E. O. Asanov, State Institution “D. F. Chebotarev Institute of Gerontology of the NAMS of Ukraine”, Kyiv

MD, PhD, DSc, Chief Researcher of the Department of Clinical Physiology and Pathology of Internal Organs

Yu. I. Holubova, State Institution “D. F. Chebotarev Institute of Gerontology of the NAMS of Ukraine”, Kyiv

Junior Researcher of the Department of Clinical Physiology and Pathology of Internal Organs

I. A. Dyba, State Institution “D. F. Chebotarev Institute of Gerontology of the NAMS of Ukraine”, Kyiv

MD, PhD, Senior Researcher of the Department of Clinical Physiology and Pathology of Internal Organs

S. O. Asanova, “Zdravo” Pharmaceutical Company, Kyiv, Ukraine

Medical Representative

References

Korkushko, O. V., Chebotarev, N. D., Pisaruk, A. V., & Asanov, E. O. (2001). Vozrastnye i patologicheskie izmeneniya ventilyatsionnoi funktsii legkikh, gazoobmena i transporta kisloroda u bol'nykh khronicheskim obstruktivnym bronkhitom pozhilogo vozrasta [Age-specific and pathological changes of lung ventilation function, gas exchange and oxygen transport in aged chronic obstructive bronchitis patients]. Ukrainskyi pulmonolohichnyi zhurnal, (1), 13-16. [in Russian].

Bush, A. (2016). Lung Development and Aging. Annals of the American Thoracic Society, 13(Suppl. 5), S438-S446. https://doi.org/10.1513/AnnalsATS.201602-112AW

Ito, K., & Barnes, P. J. (2009). COPD as a Disease of Accelerated Lung Aging. Chest, 135(1), 173-180. https://doi.org/10.1378/chest.08-1419

Brandsma, C.-A., de Vries, M., Costa, R., Woldhuis, R. R., Königshoff, M., & Timens, W. (2017). Lung ageing and COPD: is there a role for ageing in abnormal tissue repair? European Respiratory Review, 26(146), Article 170073. https://doi.org/10.1183/16000617.0073-2017

López-Campos, J. L., Tan, W., & Soriano, J. B. (2016). Global burden of COPD. Respirology, 21(1), 14-23. https://doi.org/10.1111/resp.12660

Perticone, M., Maio, R., Caroleo, B., Suraci, E., Corrao, S., Sesti, G., & Perticone, F. (2021). COPD significantly increases cerebral and cardiovascular events in hypertensives. Scientific Reports, 11(1), Article 7884. https://doi.org/10.1038/s41598-021-86963-z

Islamoglu, F., Reyhanoglu, H., Berber, O., Ozbaran, M., Buket, S., Yüksel, M., Telli, A., & Durmaz, I. (2003). Predictors of outcome after coronary artery bypass grafting in patients older than 75 years of age. Medical Science Monitor, 9(8), CR369-376. https://www.medscimonit.com/abstract/index/idArt/13104

MacNee, W. (2016). Is Chronic Obstructive Pulmonary Disease an Accelerated Aging Disease? Annals of the American Thoracic Society, 13(Suppl. 5), S429-S437. https://doi.org/10.1513/AnnalsATS.201602-124AW

Finkelstein, J., Cha, E., & Scharf, S. M. (2009). Chronic obstructive pulmonary disease as an independent risk factor for cardiovascular morbidity. International Journal of Chronic Obstructive Pulmonary Disease, 4, 337-349. https://doi.org/10.2147/copd.s6400

Dankner, R., Goldbourt, U., Boyko, V., & Reicher-Reiss, H. (2003). Predictors of cardiac and noncardiac mortality among 14,697 patients with coronary heart disease. American Journal of Cardiology, 91(2), 121-127. https://doi.org/10.1016/s0002-9149(02)03095-3

Buch, P., Friberg, J., Scharling, H., Lange, P., & Prescott, E. (2003). Reduced lung function and risk of atrial fibrillation in the Copenhagen City Heart Study. European Respiratory Journal, 21(6), 1012-1016. https://doi.org/10.1183/09031936.03.00051502

Engström, G., Wollmer, P., Hedblad, B., Juul-Möller, S., Valind, S., & Janzon, L. (2001). Occurrence and Prognostic Significance of Ventricular Arrhythmia Is Related to Pulmonary Function. A Study From «Men Born in 1914,» Malmö, Sweden. Circulation, 103(25), 3086-3091. https://doi.org/10.1161/01.cir.103.25.3086

Dvoretskii, L. I. (2005). Vedenie pozhilogo bol'nogo KhOBL [Management of COPD in older patients]. Litterra. [in Russian].

Fustey, I. M. Podsevahina, S. L. Palamarchuk, A. I. Tkachenko, O. V., & Cabanna, Е. S. (2018). Vliyanie khronicheskoi obstruktivnoi bolezni legkikh na kliniko-funktsional'noe sostoyanie miokarda u bol'nykh ishemicheskoi bolezn'yu serdtsa [The effect of chronic obstructive pulmonary disease on the clinical and functional state of myocardium in patients with ischemic heart disease]. Simeina medytsyna, (1), 73-76. http://family-medicine.com.ua/article/view/135216/132011 [in Russian].

Inomata, S., Nishikawa, T., Saito, S., & Kihara, S. (1997). «Best» PEEP during one-lung ventilation. British Journal of Anaesthesia, 78(6), 754-756. https://doi.org/10.1093/bja/78.6.754

Phoenix, S. I., Paravastu, S., Columb, M., Vincent, J. L., & Nirmalan, M. (2009). Does a Higher Positive End Expiratory Pressure Decrease Mortality in Acute Respiratory Distress Syndrome? A Systematic Review and Meta-analysis. Anesthesiology, 110(5), 1098-1105. https://doi.org/10.1097/aln.0b013e31819fae06

Putienko, Zh. E. (1999). Effektivnost' primeneniya polozhitel'nogo davleniya v kontse vydokha v korrektsii legochnoi ventilyatsii u bol'nykh bronkhial'noi astmoi i khronicheskim obstruktivnym bronkhitom [Efficiency of using positive end-expiratory pressure in correcting pulmonary ventilation in patients with bronchial asthma and chronic obstructive bronchitis]. Ukrainskyi pulmonolohichnyi zhurnal, (2), 42-44. http://www.ifp.kiev.ua/doc/journals/upj/99/upj_1999_2_ref.htm#14 [in Russian].

Asanov, E. O., & Dyba, I. A. (2018). Vliyanie dykhatel'nykh trenirovok s polozhitel'nym davleniem v kontse vydokha na ventilyatsiyu i gazoobmen v legkikh u bol'nykh pozhilogo vozrasta s KhOZL [Influence of respiratory training with positive endexpiratory pressure on the ventilation and gas exchange in lungs of elderly patients with COPD]. Ukrainskyi pulmonolohichnyi zhurnal, (3), 38-43. [in Russian].

Singh, D., Agusti, A., Anzueto, A., Barnes, P. J., Bourbeau, J., Celli, B. R., Criner, G. J., Frith, P., Halpin, D., Han, M., López Varela, M. V., Martinez, F., Montes de Oca, M., Papi, A., Pavord, I. D., Roche, N., Sin, D. D., Stockley, R., Vestbo, J., Wedzicha, J. A., … Vogelmeier, C. (2019). Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: the GOLD science committee report 2019. European Respiratory Journal, 53(5), Article 1900164. https://doi.org/10.1183/13993003.00164-2019

Boone, M. D., Jinadasa, S. P., Mueller, A., Shaefi, S., Kasper, E. M., Hanafy, K. A., O'Gara, B P., & Talmor, D. S. (2017). The Effect of Positive End-Expiratory Pressure on Intracranial Pressure and Cerebral Hemodynamics. Neurocritical Care, 26(2), 174-181. https://doi.org/10.1007/s12028-016-0328-9

Gattinoni, L., Collino, F., Maiolo, G., Rapetti, F., Romitti, F., Tonetti, T., Vasques, F., & Quintel, M. (2017). Positive end-expiratory pressure: how to set it at the individual level. Annals of Translational Medicine, 5(14), Article 288. https://doi.org/10.21037/atm.2017.06.64

Asanov, E. O., Dyba, I. A., & Osmak, E. D. (2014). Gazoobmen v legkikh u pozhilykh lyudei s fiziologicheskim i uskorennym stareniem dykhatel'noi sistemy: vliyanie dykhatel'nykh trenirovok s pozitivnym davleniem na vydokhe [Pulmonary gas exchange in elderly people with physiological and accelerated aging of the respiratory system: effect of respiratory training with positive end expiratory pressure]. Ukrainskyi pulmonolohichnyi zhurnal, (3), 64-67. http://www.ifp.kiev.ua/doc/journals/upj/14/pdf14-3/64.pdf [in Russian].

Published

2021-10-29

How to Cite

1.
Asanov EO, Holubova YI, Dyba IA, Asanova SO. Breathing exercises with PEEP: efficiency and duration for correcting the cardiovascular system functional state in older patients with COPD. Zaporozhye Medical Journal [Internet]. 2021Oct.29 [cited 2024Oct.5];23(6):806-12. Available from: http://zmj.zsmu.edu.ua/article/view/231350

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Section

Original research