Ozone therapy as a component of a comprehensive rehabilitation program for patients after polysegmental pneumonia associated with SARS-CoV2 infection

Authors

DOI:

https://doi.org/10.14739/2310-1210.2021.6.233891

Keywords:

rehabilitation, ozonotherapy, pneumonia viral, SARS-CoV2 infection, long-term COVID-19

Abstract

Aim: to analyze the effectiveness of intravenous ozone therapy in long COVID-19 patients experienced community-acquired polysegmental pneumonia (associated with SARS-CoV2 infection).

Materials and methods. The study involved 42 long COVID-19 individuals aged 41–82 years who underwent rehabilitation after community-acquired polysegmental pneumonia associated with SARS-CoV2 infection. The patients were examined and followed up subjectively (by the G. Borg and PCFS scales) and objectively (oxygen saturation, C-reactive protein, ferritin, D-dimer, urea and creatinine, 6-minute walk test).

All patients received similar medicamentous therapy, and combined intravenous ozone therapy was additionally prescribed to the main group patients (n = 21): an alternate-day infusion of 200 ml ozonized saline at a concentration of 20 mg/ml and major autohemotherapy (100 ml ozonized saline at a concentration of 30 mg/ml mixed with 100 ml of the patient’s blood), 10 sessions per treatment course.

Results. The integrated approach to the complex program of long COVID-19 treatment and rehabilitation for patients after pneumonia associated with SARS-CoV2 infection using intravenous ozone therapy has demonstrated its significant effectiveness based on the objective and subjective findings (P < 0.01).

Twice as many patients in the main group (n = 18) achieved endpoints of the study (absence of dyspnea, normalization of blood biochemical markers and oxygen saturation levels, restoration of exercise tolerance) as compared to the control group (n = 9).

Conclusions. The use of combined intravenous ozone therapy (alternating infusion of ozonized saline and ozonized saline mixed with the patient’s blood) in the rehabilitation program for patients after experienced community-acquired polysegmental pneumonia associated with SARS-CoV2 infection is pathogenetically substantiated, effective and cost-effective addition to complex health recovery tools.

Author Biographies

I. B. Baranova, National Pirogov Memorial Medical University, Vinnytsia, Ukraine

MD, PhD, Associate Professor of the Department of Physical and Rehabilitation Medicine; Head of the Department of Rehabilitation, University Clinic of National Pirogov Memorial Medical University, Vinnytsia, Ukraine

A. F. Gumeniuk, National Pirogov Memorial Medical University, Vinnytsia, Ukraine

MD, PhD, Associate Professor of the Department of Internal Medicine of the Medical Faculty №2

A. I. Semenenko, National Pirogov Memorial Medical University, Ukraine

MD, PhD, DSc, Professor  of the Department of Anesthesiology, Intensive care and Emergency Medicine; Director of the University Clinic

I. A. Iliuk, National Pirogov Memorial Medical University, Vinnytsia, Ukraine

MD, PhD, Associate Professor of the Department of Internal Medicine №2

I. P. Osypenko, National Pirogov Memorial Medical University, Vinnytsia, Ukraine

MD, PhD, Assistant of the Department of Internal Medicine No. 2

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Published

2021-11-03

How to Cite

1.
Baranova IB, Gumeniuk AF, Semenenko AI, Iliuk IA, Osypenko IP. Ozone therapy as a component of a comprehensive rehabilitation program for patients after polysegmental pneumonia associated with SARS-CoV2 infection. Zaporozhye Medical Journal [Internet]. 2021Nov.3 [cited 2026May15];23(6):752-8. Available from: https://zmj.zsmu.edu.ua/article/view/233891

Issue

Vol. 23 No. 6 (2021)

Section

Original research

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