Features of the left ventricle diastolic function in patients with community acquired pneumonia
DOI:
https://doi.org/10.14739/2310-1210.2014.2.25322Keywords:
community-acquired pneumonia, diastolic function, left ventricleAbstract
Introduction. One of the major factors considered unfavorable clinical course of central and peripheral hemodynamics, identifying them with a view to the timely correction, is a promising direction to improve prognosis in patients with community acquired pneumonia. There are still conflicting data on the characteristics of disorders of left ventricular diastolic filling in patients with pneumonia
Aim of this work was to study the characteristics of diastolic filling of the left ventricle in patients with community acquired pneumonia of the third group.
Material and methods. 50 patients with community acquired pneumonia the third group and 30 healthy individuals were included in an open prospective study. All patients were performed transthoracic echocardiography by ultrasound diagnostic device «My Lab 50 CV XVision» («Esaote», Italy) using a phased probe RA230E 2-4 MHz («Esaote», Italy).
Results. Patients with community acquired pneumonia third group have increased right ventricular systolic function, remains unchanged left ventricular ejection fraction due to the likely increase in its linear and volumetric performance and reducing the total peripheral vascular resistance (TPVR) 53.8 % (p < 0.05) and significantly improves diastolic filling of the left ventricle, growth contribution of early ventricular filling by 14.7 % (p < 0.05), reducing the systolic diameter of the left atrium 9.2 % (p=0.039) and diastolic intramural myocardial pressure at 24.0 % (p < 0.05), decreased pulmonary capillaries wedge pressure (PCWP) by 11.8 % (p< 0.05) and the average pulmonary artery pressure by 20.9 % (p<0.05). Patients with community acquired pneumonia have "small hemodynamic profile ": PCWP low, normal LVEF, low TPVR.
Conclusions.
Positive changes in left ventricular diastolic filling: increase the contribution of early ventricular filling, reducing the diameter of the left atrium in systole, reducing diastolic intramural myocardial pressure, decreased pulmonary capillaries wedge pressure and average pressure in the pulmonary artery were observed in patients with community acquired pneumonia. Patients with community acquired pneumonia remains unchanged LV ejection fraction due to the likely increase in linear and volumetric parameters of LV and reducing the total peripheral vascular resistance, and increased systolic function of the right ventricle.
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