New approaches to reduce ulcerogenity of nonsteroidal anti-inflammatory drugs: achievements, unsolved issues and ways to optimize
DOI:
https://doi.org/10.14739/2310-1210.2014.2.25437Keywords:
NSAID-induced gastropathy, Ibuprofen, Vinboron, QuercetinAbstract
Analysis of the domestic and foreign literature sources devoted to the study of pathogenetic mechanisms of gastropathy caused by non-steroidal anti-inflammatory drugs was done. Current approaches of prevention and treatment of NSAID-induced gastropathy were lined. The appropriateness of drugs with polytropic pharmacological properties (Quercetin, Vinboron and Tiotriazolin) to eliminate the side effects of NSAIDs, including ultserogenesis was discusses.
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