Gender, age and morphofunctional characteristics of the quality of life of patients with stable angina

Authors

DOI:

https://doi.org/10.14739/2310-1210.2023.1.268081

Keywords:

stable angina, life quality

Abstract

Aim of the work is to investigate the quality of life (QoL) of patients with stable angina pectoris (SA) depending on gender, age distribution and severity of angina pectoris.

Materials and methods. 78 patients with an objective diagnosis of functional classes (FC) II–III SA were examined, who formed two clinical groups: the 1st – patients with an increase in QoL (57.69 % of cases), the 2nd – patients with the absence of any changes in QoL (42.31 % of cases). All patients underwent clinical, laboratory, instrumental examinations and determination of QoL using the SF-36 questionnaire.

Results. The study of the QoL in men revealed that the mental component (MHC) of health was significantly higher due to such indicators as vitality (VT) (P < 0.001), mental health (MH) (P < 0.001), social functioning (SF) (Р = 0.028), general health status (GHS) (Р < 0.001). Younger age was characterized by a higher physical component of health (PHC) due to significantly higher indicators such as physical functioning (PF) and role-based physical functioning (RBPF) (in both cases P < 0.001). In the subgroup of younger women, the PHC was higher due to significantly higher levels of PF and RBPF (P = 0.048 and P = 0.011, respectively), that could be compared with the indicators of younger men, where the PHC was also higher due to GHS (Р = 0.009), RBPF (P = 0.028) and PF (P = 0.050). In men of younger age, the indicator of VT was significantly higher (Р = 0.031).

Patients with higher FC of SA were expected to have a significant limitation of QoL in the form of a lower PHC (GHS (P = 0.023), PF (P < 0.001), RBPF (P < 0.001) and pain intensity (PI) (P < 0.001)). With the progression of heart failure (HF), GHS (P = 0.003), PF (P < 0.001), RBPF (P < 0.001) and PI (P < 0.001) significantly worsened. It was confirmed that the increase of QoL did not depend on gender (women P = 0.204, men P = 0.226) and age (P = 0.143). The presence of excess body weight was characterized by limitation of physical (significantly lower indicators of PF (P = 0.010) and PI (P = 0.008)) and mental (significantly decreased indicator – P = 0.053) health.

Conclusions. Positive dynamics of the quality of life is associated with a lower functional class of stable angina pectoris, lower severity of heart failure, favorable shifts in the lipid spectrum, an increase in the left ventricular ejection fraction and the threshold load of cycle ergometry. The physical component of health is decisive in the quality of life of patients with stable angina pectoris.

Author Biographies

V. K. Tashchuk, Bukovinіan State Medical University, Chernivtsi, Ukraine

MD, PhD, DSc, Professor, Head of the Department of Internal Medicine, Physical Rehabilitation and Sport Medicine

T. М. Amelina, Bukovinian State Medical University, Chernivtsi, Ukraine

MD, PhD, Associate Professor of the Department of Internal Medicine, Physical Rehabilitation and Sport Medicine

P. R. Ivanchuk, Bukovinian State Medical University, Chernivtsi, Ukraine

MD, PhD, Associate Professor of the Department of Internal Medicine, Physical Rehabilitation and Sport Medicine

M. A. Ivanchuk, Bukovinian State Medical University, Chernivtsi, Ukraine

PhD, Associate Professor of the Department of Biological Physics and Medical Informatics

References

Orsini, E., Marzilli, M., Zito, G. B., Carbone, V., Latina, L., Oliviero, U., Rizzo, U., & ARCA Registry Investigators (2022). Clinical outcomes of newly diagnosed, stable angina patients managed according to current guidelines. The ARCA (Arca Registry for Chronic Angina) Registry: A prospective, observational, nationwide study. International journal of cardiology, 352, 9-18. https://doi.org/10.1016/j.ijcard.2022.01.056

Huzmeli, I., Ozer, A. Y., Akkus, O., Katayıfcı, N., Sen, F., Yurdalan, S. U., & Polat, M. G. (2020). Comparison of functional exercise capacity, quality of life and respiratory and peripheral muscle strength between patients with stable angina and healthy controls. The Journal of international medical research, 48(12), 300060520979211. https://doi.org/10.1177/0300060520979211

Mehta, S. R., Wang, J., Wood, D. A., Spertus, J. A., Cohen, D. J., Mehran, R., Storey, R. F., Steg, P. G., Pinilla-Echeverri, N., Sheth, T., Bainey, K. R., Bangalore, S., Cantor, W. J., Faxon, D. P., Feldman, L. J., Jolly, S. S., Kunadian, V., Lavi, S., Lopez-Sendon, J., Madan, M., … COMPLETE Trial Investigators (2022). Complete Revascularization vs Culprit Lesion-Only Percutaneous Coronary Intervention for Angina-Related Quality of Life in Patients With ST-Segment Elevation Myocardial Infarction: Results From the COMPLETE Randomized Clinical Trial. JAMA cardiology, 7(11), 1091-1099. https://doi.org/10.1001/jamacardio.2022.3032

Zhang, H., Wang, Y., Cai, X., Tang, N., Wei, S., & Yang, Y. (2022). Family functioning and health-related quality of life of inpatients with coronary heart disease: a cross-sectional study in Lanzhou city, China. BMC cardiovascular disorders, 22(1), 397. https://doi.org/10.1186/s12872-022-02844-x

Harwell, S. M., Tomlinson, J. S., & Brady, A. J. (2022). Diagnosis and management of stable angina in primary care. InnovAiT: Education and Inspiration for General Practice, 15(6), 362–369. https://doi.org/10.1177/17557380221084730

Schopfer, D. W., Beatty, A. L., Meyer, C. S., & Whooley, M. A. (2022). Longitudinal Association Between Angina Pectoris and Quality of Life. The American journal of cardiology, 164, 1-6. https://doi.org/10.1016/j.amjcard.2021.10.037

Mayer, O., Jr, Bruthans, J., Seidlerová, J., Karnosová, P., Mateřánková, M., Gelžinský, J., Rychecká, M., Cífková, R., & Filipovský, J. (2020). Mood disorders impaired quality of life but not the mortality or morbidity risk in stable coronary heart disease patients. Acta cardiologica, 75(7), 667-675. https://doi.org/10.1080/00015385.2019.1653568

Nowbar, A. N., Francis, D. P., & Al-Lamee, R. K. (2022). Quality of Life Assessment in Trials of Revascularization for Chronic Stable Angina: Insights from ORBITA and the Implications of Blinding. Cardiovascular drugs and therapy, 36(5), 1011-1018. https://doi.org/10.1007/s10557-021-07198-8

Patel, K. K. (2022). Improving Symptoms and Quality of Life in Stable Coronary Artery Disease: An Evolving Paradigm. Circulation, 145(17), 1308-1311. https://doi.org/10.1161/CIRCULATIONAHA.122.059482

Spoletini, I., Ferrari, R., & Rosano, G. M. C. (2020). Living with stable angina: patients' pathway and needs in angina. Journal of cardiovascular medicine (Hagerstown, Md.), 21(5), 377-382. https://doi.org/10.2459/JCM.0000000000000954

Published

2023-03-06

How to Cite

1.
Tashchuk VK, Amelina TМ, Ivanchuk PR, Ivanchuk MA. Gender, age and morphofunctional characteristics of the quality of life of patients with stable angina. Zaporozhye Medical Journal [Internet]. 2023Mar.6 [cited 2024Jul.17];25(1):16-22. Available from: http://zmj.zsmu.edu.ua/article/view/268081