Gender, age and morphofunctional characteristics of the quality of life of patients with stable angina
DOI:
https://doi.org/10.14739/2310-1210.2023.1.268081Keywords:
stable angina, life qualityAbstract
Aim of the work is to investigate the quality of life (QoL) of patients with stable angina pectoris (SA) depending on gender, age distribution and severity of angina pectoris.
Materials and methods. 78 patients with an objective diagnosis of functional classes (FC) II–III SA were examined, who formed two clinical groups: the 1st – patients with an increase in QoL (57.69 % of cases), the 2nd – patients with the absence of any changes in QoL (42.31 % of cases). All patients underwent clinical, laboratory, instrumental examinations and determination of QoL using the SF-36 questionnaire.
Results. The study of the QoL in men revealed that the mental component (MHC) of health was significantly higher due to such indicators as vitality (VT) (P < 0.001), mental health (MH) (P < 0.001), social functioning (SF) (Р = 0.028), general health status (GHS) (Р < 0.001). Younger age was characterized by a higher physical component of health (PHC) due to significantly higher indicators such as physical functioning (PF) and role-based physical functioning (RBPF) (in both cases P < 0.001). In the subgroup of younger women, the PHC was higher due to significantly higher levels of PF and RBPF (P = 0.048 and P = 0.011, respectively), that could be compared with the indicators of younger men, where the PHC was also higher due to GHS (Р = 0.009), RBPF (P = 0.028) and PF (P = 0.050). In men of younger age, the indicator of VT was significantly higher (Р = 0.031).
Patients with higher FC of SA were expected to have a significant limitation of QoL in the form of a lower PHC (GHS (P = 0.023), PF (P < 0.001), RBPF (P < 0.001) and pain intensity (PI) (P < 0.001)). With the progression of heart failure (HF), GHS (P = 0.003), PF (P < 0.001), RBPF (P < 0.001) and PI (P < 0.001) significantly worsened. It was confirmed that the increase of QoL did not depend on gender (women P = 0.204, men P = 0.226) and age (P = 0.143). The presence of excess body weight was characterized by limitation of physical (significantly lower indicators of PF (P = 0.010) and PI (P = 0.008)) and mental (significantly decreased indicator – P = 0.053) health.
Conclusions. Positive dynamics of the quality of life is associated with a lower functional class of stable angina pectoris, lower severity of heart failure, favorable shifts in the lipid spectrum, an increase in the left ventricular ejection fraction and the threshold load of cycle ergometry. The physical component of health is decisive in the quality of life of patients with stable angina pectoris.
References
Orsini, E., Marzilli, M., Zito, G. B., Carbone, V., Latina, L., Oliviero, U., Rizzo, U., & ARCA Registry Investigators (2022). Clinical outcomes of newly diagnosed, stable angina patients managed according to current guidelines. The ARCA (Arca Registry for Chronic Angina) Registry: A prospective, observational, nationwide study. International journal of cardiology, 352, 9-18. https://doi.org/10.1016/j.ijcard.2022.01.056
Huzmeli, I., Ozer, A. Y., Akkus, O., Katayıfcı, N., Sen, F., Yurdalan, S. U., & Polat, M. G. (2020). Comparison of functional exercise capacity, quality of life and respiratory and peripheral muscle strength between patients with stable angina and healthy controls. The Journal of international medical research, 48(12), 300060520979211. https://doi.org/10.1177/0300060520979211
Mehta, S. R., Wang, J., Wood, D. A., Spertus, J. A., Cohen, D. J., Mehran, R., Storey, R. F., Steg, P. G., Pinilla-Echeverri, N., Sheth, T., Bainey, K. R., Bangalore, S., Cantor, W. J., Faxon, D. P., Feldman, L. J., Jolly, S. S., Kunadian, V., Lavi, S., Lopez-Sendon, J., Madan, M., … COMPLETE Trial Investigators (2022). Complete Revascularization vs Culprit Lesion-Only Percutaneous Coronary Intervention for Angina-Related Quality of Life in Patients With ST-Segment Elevation Myocardial Infarction: Results From the COMPLETE Randomized Clinical Trial. JAMA cardiology, 7(11), 1091-1099. https://doi.org/10.1001/jamacardio.2022.3032
Zhang, H., Wang, Y., Cai, X., Tang, N., Wei, S., & Yang, Y. (2022). Family functioning and health-related quality of life of inpatients with coronary heart disease: a cross-sectional study in Lanzhou city, China. BMC cardiovascular disorders, 22(1), 397. https://doi.org/10.1186/s12872-022-02844-x
Harwell, S. M., Tomlinson, J. S., & Brady, A. J. (2022). Diagnosis and management of stable angina in primary care. InnovAiT: Education and Inspiration for General Practice, 15(6), 362–369. https://doi.org/10.1177/17557380221084730
Schopfer, D. W., Beatty, A. L., Meyer, C. S., & Whooley, M. A. (2022). Longitudinal Association Between Angina Pectoris and Quality of Life. The American journal of cardiology, 164, 1-6. https://doi.org/10.1016/j.amjcard.2021.10.037
Mayer, O., Jr, Bruthans, J., Seidlerová, J., Karnosová, P., Mateřánková, M., Gelžinský, J., Rychecká, M., Cífková, R., & Filipovský, J. (2020). Mood disorders impaired quality of life but not the mortality or morbidity risk in stable coronary heart disease patients. Acta cardiologica, 75(7), 667-675. https://doi.org/10.1080/00015385.2019.1653568
Nowbar, A. N., Francis, D. P., & Al-Lamee, R. K. (2022). Quality of Life Assessment in Trials of Revascularization for Chronic Stable Angina: Insights from ORBITA and the Implications of Blinding. Cardiovascular drugs and therapy, 36(5), 1011-1018. https://doi.org/10.1007/s10557-021-07198-8
Patel, K. K. (2022). Improving Symptoms and Quality of Life in Stable Coronary Artery Disease: An Evolving Paradigm. Circulation, 145(17), 1308-1311. https://doi.org/10.1161/CIRCULATIONAHA.122.059482
Spoletini, I., Ferrari, R., & Rosano, G. M. C. (2020). Living with stable angina: patients' pathway and needs in angina. Journal of cardiovascular medicine (Hagerstown, Md.), 21(5), 377-382. https://doi.org/10.2459/JCM.0000000000000954
Downloads
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)
