Relationship between enamel resistance and physical properties of saliva in drug-addicted patients
DOI:
https://doi.org/10.14739/2310-1210.2023.2.273629Keywords:
dental caries, drug addiction, enamel resistance, salivaAbstract
Aim. To investigate the relationship between the physical properties of saliva and enamel resistance and caries intensity in drug-addicted patients.
Materials and methods. The study involved 70 patients, who were divided into three groups: the main group (1) – 28 drug addicts diagnosed with caries, the comparison group (2) – 22 patients with caries of dental hard tissues without a history of drug addiction, and the control group (3) – 20 persons without carious lesions of dental hard tissues. We examined the rate of salivation, which was calculated by the formula: Rs = V / T, pH of oral fluid using litmus test strips (Kelilong Instruments, China), structural and functional stability of tooth enamel by the express method TER-test (V. R. Okushko, L. I. Kosareva, 1983), clinically assessed the rate of mineralization according to the Clinical Assessment of the Rate of Enamel Remineralization-test (T. L. Redinova, V. K. Leontiev and G. D. Ovrutsky, 1982), dental caries intensity using the DMF index; the International Caries Detection and Assessment System (ICDAS) was used to assess of the dental hard tissues.
Results. In drug-addicted patients with caries of dental hard tissues, the slowest rate of salivation and significant changes in the oral fluid pH toward acidic were observed, namely 5.5 ± 0.09 units compared with patients of other groups. In drug addicts, the average TER-test score was 9.1 ± 0.4 points and was significantly higher than that in non-drug-addicted patients with dental caries (5.4 ± 0.2 points) and people without dental caries (1.9 ± 0.2 points). The Clinical Assessment of the Rate of Enamel Remineralization-test indicators of drug-addicted patients (6.1 ± 0.3 days) were also significantly higher than those of non-addicted and control group patients. The DMF index in drug-addicted patients was 16.4 ± 0.2 points showing a very high intensity of caries with a large proportion of deep carious lesions in the dental hard tissues.
Conclusions. In drug addicts, the study results have indicated a 23 % pH shift of the oral fluid toward acidic, and a 22 % decrease in the rate of saliva secretion has also been recorded compared to the healthy individuals. These results were associated with a 79 % decrease in the tooth enamel durability and a 66 % decrease in the remineralizing capacity of the oral fluid in drug addicts as compared to the healthy individuals. The DMF index of group 1 patients differed from that of group 2 patients by 50 % and from group 3 individuals – by 98 %. Drug-addicted patients had 78 % more carious lesions in the dentin compared to non-drug-addicted patients with dental caries.
References
State Institution «Institute of Psychiatry, Forensic Psychiatric Examination and Drug Monitoring of the Ministry of Health of Ukraine». (2021). Natsionalnyi Zvit shchodo narkotychnoi sytuatsii v Ukraini za 2021 rik (za danymy 2020 roku) [National Report on the Drug Situation in Ukraine for 2021 (according to 2020)]. https://cmhmda.org.ua/report/zvit-za-2021-rik/
Topchii, V. V., & Terpuhova, T. V. (2017). Kryminolohichna kharakterystyka ta zapobihannia narkotyzmu v Ukraini [Criminological characteristics and prevention of drug addiction in Ukraine]. Mizhnarodnyi yurydychnyi visnyk: aktualni problemy suchasnosti (teoriia ta praktyka), (4-5), 60-65. [in Ukrainian].
Herych, I. D., Iftodii, A. H., & Biltsan, O. V. (2015). Khirurhichni uskladnennia iniektsiinoi narkomanii: problemy ta osoblyvosti likuvannia: monohrafiia [Surgical complications of injection drug addiction: problems and features of treatment]. Chernivtsi: Bukrek [in Ukrainian].
Fedun, I. R., & Zubachyk, V. M. (2018). Struktura ta klinichna otsinka zakhvoriuvan tkanyn parodontu u narkozalezhnykh patsiientiv [Structure and clinical evaluation of periodontal diseases in drug addict patients]. World of Medicine and Biology, (3), 124-128 [in Ukrainian]. https://doi.org/10.26724/2079-8334-2018-3-65-124-128
Fedun, I. R., Furdychko, A. I., Ilchyshyn, M. P., Baryliak, A. Ya., Han, I. V., & Vozny, O. V. (2020). Vplyv narkozalezhnosti na patolohiiu porozhnyny rota ta osoblyvosti nadannia stomatolohichnoi dopomohy narkozalezhnym khvorym [Influence of drug addiction on oral pathology and peculiarities of dental care for drug addicts (literature review)]. Zaporozhye medical journal, 22(6), 858-864 [in Ukrainian]. https://doi.org/10.14739/2310-1210.2020.6.218473
Hossain, K. M. S., Kakoli, A. S., Mesbah, F. B, & Mian, A. H. (2018). Prevalence of Oral and Dental Diseases and Oral Hygiene Practices among Illicit Drug Abusers. Journal of Alcoholism & Drug Dependence, 06(01). https://doi.org/10.4172/2329-6488.1000301
Owlia, F., Karbassi, M. H. A., Sadeghipour, M., & Behnia, A. (2017). Evaluating of cervical caries and periodontitis among drug abusers in an Iranian population. Annual Research and Review in Biology, 12(3). https://doi.org/10.9734/ARRB/2017/31183
Yazdanian, M., Armoon, B., Noroozi, A., Mohammadi, R., Bayat, A. H., Ahounbar, E., Higgs, P., Nasab, H. S., Bayani, A., & Hemmat, M. (2020). Dental caries and periodontal disease among people who use drugs: a systematic review and meta-analysis. BMC oral health, 20(1), 44. https://doi.org/10.1186/s12903-020-1010-3
Auger, N., Low, N., Lee, G., Ayoub, A., & Nicolau, B. (2020). Prenatal Substance Use Disorders and Dental Caries in Children. Journal of dental research, 99(4), 395-401. https://doi.org/10.1177/0022034520906820
Malanchuk, V. O., Kopchak, A. V., & Brodetskyi, I. S. (2007). Klinichni osoblyvosti osteomiielitu shchelep u khvorykh z narkotychnoiu zalezhnistiu [Clinical features of osteomyelitis of the jaws in patients with drug addiction]. Ukrainskyi medychnyi chasopys, (4), 111-117. [in Ukrainian].
Chukhray, N. L., Mashkarynetz, O. O., Chemerys, O. M., & Musij-Sementsiv, Kh. H. (2019). Relationship between oral fluid pH, dental caries and enamel resistance in children. World of Medicine and Biology, (1), 107-111. https://doi.org/10.26724/2079-8334-2019-1-67-107
Kulygina, V. M., & Pylypiuk, O. Yu. (2016). Rezultaty vyvchennia kariiesspryiatlyvosti emali zubiv ta remineralizuiuchoho potentsialu zmishanoi slyny u ditei z yuvenilnym revmatoidnym artrytom [Results of the study of caries-susceptibility of the dental enamel and remineralizing potential of the mixed saliva in the children with juvenile rheumatoid arthritis]. Visnyk problem biolohii i medytsyny, 3(2), 359-362. [in Ukrainian].
Melnik, V., Gorzov, L., Melnik, S., & Duganchik, Y. (2021). Otsinka karioznykh urazhen zubiv za kryteriiem indeksu ICDAS II [Assessment of dental carious lesions by ICDAS II]. Actual Problems of the Modern Medicine: Bulletin of Ukrainian Medical Stomatological Academy, 21(1), 76-80. [in Ukrainian]. https://doi.org/10.31718/2077-1096.21.1.76
Dikmen B. (2015). Icdas II criteria (international caries detection and assessment system). Journal of Istanbul University Faculty of Dentistry, 49(3), 63-72. https://doi.org/10.17096/jiufd.38691
Kanehira, T., Takehara, J., Nakamura, K., Hongo, H., Miyake, R., & Takahashi, D. (2017). The ICDAS (International Caries Detection & Assessment System): a new set of caries assessment criteria. Journal of Dental Sciences, 38, 180-183.
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