Relationship between enamel resistance and physical properties of saliva in drug-addicted patients

Authors

DOI:

https://doi.org/10.14739/2310-1210.2023.2.273629

Keywords:

dental caries, drug addiction, enamel resistance, saliva

Abstract

Aim. To investigate the relationship between the physical properties of saliva and enamel resistance and caries intensity in drug-addicted patients.

Materials and methods. The study involved 70 patients, who were divided into three groups: the main group (1) – 28 drug addicts diagnosed with caries, the comparison group (2) – 22 patients with caries of dental hard tissues without a history of drug addiction, and the control group (3) – 20 persons without carious lesions of dental hard tissues. We examined the rate of salivation, which was calculated by the formula: Rs = V / T, pH of oral fluid using litmus test strips (Kelilong Instruments, China), structural and functional stability of tooth enamel by the express method TER-test (V. R. Okushko, L. I. Kosareva, 1983), clinically assessed the rate of mineralization according to the Clinical Assessment of the Rate of Enamel Remineralization-test (T. L. Redinova, V. K. Leontiev and G. D. Ovrutsky, 1982), dental caries intensity using the DMF index; the International Caries Detection and Assessment System (ICDAS) was used to assess of the dental hard tissues.

Results. In drug-addicted patients with caries of dental hard tissues, the slowest rate of salivation and significant changes in the oral fluid pH toward acidic were observed, namely 5.5 ± 0.09 units compared with patients of other groups. In drug addicts, the average TER-test score was 9.1 ± 0.4 points and was significantly higher than that in non-drug-addicted patients with dental caries (5.4 ± 0.2 points) and people without dental caries (1.9 ± 0.2 points). The Clinical Assessment of the Rate of Enamel Remineralization-test indicators of drug-addicted patients (6.1 ± 0.3 days) were also significantly higher than those of non-addicted and control group patients. The DMF index in drug-addicted patients was 16.4 ± 0.2 points showing a very high intensity of caries with a large proportion of deep carious lesions in the dental hard tissues.

Conclusions. In drug addicts, the study results have indicated a 23 % pH shift of the oral fluid toward acidic, and a 22 % decrease in the rate of saliva secretion has also been recorded compared to the healthy individuals. These results were associated with a 79 % decrease in the tooth enamel durability and a 66 % decrease in the remineralizing capacity of the oral fluid in drug addicts as compared to the healthy individuals. The DMF index of group 1 patients differed from that of group 2 patients by 50 % and from group 3 individuals – by 98 %. Drug-addicted patients had 78 % more carious lesions in the dentin compared to non-drug-addicted patients with dental caries.

Author Biographies

I. R. Fedun, Danylo Halytsky Lviv National Medical University, Ukraine

MD, PhD, Assistant of the Department of Therapeutic Dentistry

V. M. Zubachyk, Danylo Halytsky Lviv National Medical University, Ukraine

MD, PhD, DSc, Professor, Head of the Department of Therapeutic Dentistry

A. I. Furdychko, Danylo Halytsky Lviv National Medical University, Ukraine

MD, PhD, DSc, Associate Professor of the Department of Therapeutic Dentistry

I. V. Han, Danylo Halytsky Lviv National Medical University, Ukraine

MD, PhD, Assistant of the Department of Therapeutic Dentistry

M. P. Ilchyshyn, Danylo Halytsky Lviv National Medical University, Ukraine

MD, PhD, Assistant of the Department of Therapeutic Dentistry

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Published

2023-03-28

How to Cite

1.
Fedun IR, Zubachyk VM, Furdychko AI, Han IV, Ilchyshyn MP. Relationship between enamel resistance and physical properties of saliva in drug-addicted patients. Zaporozhye Medical Journal [Internet]. 2023Mar.28 [cited 2024Nov.25];25(2):147-52. Available from: http://zmj.zsmu.edu.ua/article/view/273629