Approaches to predicting life expectancy in elderly coronary artery disease patients with comorbid conditions

Authors

DOI:

https://doi.org/10.14739/2310-1210.2023.5.280007

Keywords:

coronary artery disease, comorbidity, older age, life expectancy

Abstract

The aim of the study was to develop a model for predicting the probability of survival up to 80 years of age for elderly and senile patients with coronary artery disease (CAD) and concomitant conditions.

Materials and methods. A retrospective data analysis of elderly and senile CAD patients who were observed in the period 1997–2019 and died from a cardiovascular event.

Results. Using binary logistic regression analysis, a model of the survival probability up to 80 years in CAD patients with comorbid conditions has been developed. The overall accuracy of the model was 83.12 % (χ2 = 6.70, p < 0.05), and the predictive accuracy of the model (AUC = 0.853, 95 % CI 0.802–0.896) was sufficiently high and adequate to use in clinical practice. Odds ratio has shown a greater contribution of arterial hypertension and diabetes mellitus to reduced probabilities of surviving to the age of 80, a less significant contribution – of chronic obstructive pulmonary disease and dyslipidemia.

Conclusions. The developed model for predicting the survival probability up to 80 years for older age group patients with coronary artery disease and comorbid conditions can be used to evaluate the effectiveness and correct medical and preventive measures.

Author Biographies

E. O. Asanov, SI “D. F. Chebotarov Institute of Gerontology of the NAMS of Ukraine”, Kyiv

MD, PhD, DSc, Chief Researcher of the Department of Clinical Physiology and Pathology of Internal Organs

G. P. Voinarovska, SI “D. F. Chebotarov Institute of Gerontology of the NAMS of Ukraine”, Kyiv

MD, PhD, Junior Researcher of the Department of Clinical Physiology and Pathology of Internal Organs

I. A. Dyba, SI “D. F. Chebotarov Institute of Gerontology of the NAMS of Ukraine”, Kyiv

MD, PhD, Senior Researcher of the Department of Clinical Physiology and Pathology of Internal Organs

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Published

2023-09-28

How to Cite

1.
Asanov EO, Voinarovska GP, Dyba IA. Approaches to predicting life expectancy in elderly coronary artery disease patients with comorbid conditions. Zaporozhye Medical Journal [Internet]. 2023Sep.28 [cited 2024May19];25(5):391-4. Available from: http://zmj.zsmu.edu.ua/article/view/280007