Relationship of hyperglycemia with endothelial function, renal function, lipidemic profile, and morphological changes of blood cells in patients with insufficient compensation of type 2 diabetes mellitus with hypertension

Authors

  • N. O. Pertseva

DOI:

https://doi.org/10.14739/2310-1210.2014.6.35636

Keywords:

Diabetes Mellitus Type 2, Arterial Hypertension, Endothelium, Thrombocytosis, Hemostasis

Abstract

Many questions about the relationship between endothelial dysfunction and morphological substrate of hemostasis damage that occur during the progress of type 2 diabetes mellitus and arterial hypertension require clarification and further advance. In 87 patients with insufficient glycemic compensation using clinical, laboratory, morphological methods and correlational analysis were identified association between endothelial dysfunction, degree of renal function damage, lipidemic profile and morphological changes of vascular-platelet hemostasis. It has been established that in the insufficient glycemic control by a significant strengthening relationships between indicators of endothelial dysfunction and damaged platelet hemostasis (up to r=+0.95) formed significant correlations of ultrastructural characteristics of platelets with clinical and laboratory signs of nephropathic and dyslipidemic changes.

References

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How to Cite

1.
Pertseva NO. Relationship of hyperglycemia with endothelial function, renal function, lipidemic profile, and morphological changes of blood cells in patients with insufficient compensation of type 2 diabetes mellitus with hypertension. Zaporozhye Medical Journal [Internet]. 2014Dec.8 [cited 2024Nov.14];16(6). Available from: http://zmj.zsmu.edu.ua/article/view/35636

Issue

No. 6 (2014): Zaporozhye medical journal

Section

Original research

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