Influence of artificial hypothermia and simvastatin on cognitive function in patients with intracranial aneurism hemorrhages

Authors

  • S. O. Dudukina

DOI:

https://doi.org/10.14739/2310-1210.2015.2.42019

Keywords:

Intracranial Hemorrhages, Cognitive Aspects, Simvastatin, Hypothermia

Abstract

Aim. Influence of prophylactic and treatment methods of secondary brain ischemia on cognitive function conditions is not studied enough.

Methods and results. To estimate influence of alternative prophylactic methods and methods of secondary brain ischemia on life quality in patients with intracranial aneurism hemorrhages after operation according to MMSE scale for cognitive function at hospital discharge was defined in 6 months and 2.5 years after treatment.

Conclusion. It was found that usage of prophylactic hypothermia and simvastatin didn’t influence on cognitive function. Usage of therapeutic hypothermia in patients with complicated progressive intracranial aneurism hemorrhages improves cognitive functions in the post operative period, especially, function of orientation, memory, speech, an order of instructions execution, especially 2.5 years after operative treatment.

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1.
Dudukina SO. Influence of artificial hypothermia and simvastatin on cognitive function in patients with intracranial aneurism hemorrhages. Zaporozhye medical journal [Internet]. 2015Apr.27 [cited 2024Apr.20];17(2). Available from: http://zmj.zsmu.edu.ua/article/view/42019

Issue

No. 2 (2015): Zaporozhye medical journal

Section

Original research

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