Кальциневрин как маркер гипертрофии миокарда у детей с клапанными врождёнными пороками сердца

A. V. Kamenshchyk; T. B. Borisenko; T. F. Antishina; E. I. Rudova

doi:10.14739/2310-1210.2015.3.44446

Authors

A. V. Kamenshchyk
T. B. Borisenko
T. F. Antishina
E. I. Rudova

DOI:

https://doi.org/10.14739/2310-1210.2015.3.44446

Keywords:

Calcineurin, Congenital Valvular Heart Diseases, Children

Abstract

Aim. To identify interrelations between the calcineurin levels in children with valvular congenital heart diseases without heart failure and the echocardiography parameters of myocardial hypertrophy.

Results: It was established the significantly decreased calcineurin level in congenial valvular heart diseases in children as well as an absence of correlations of the left ventricle myocardial mass and index with negative ones to the dimensions of right ventricle in comparison to healthy children of corresponding age.

Conclusion: The obtained data testifies the importance of calcineurin system activity in the formation of pathologic myocardial hypertrophy in children with valvular congenital heart diseases and without manifestation of heart failure.

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