Clinical and paraclinical criteria for prognosis of the hemorrhagic transformation of hemispheric cerebral infarction and its influence on the outcome of the acute period of the disease
DOI:
https://doi.org/10.14739/2310-1210.2015.3.44492Keywords:
Brain Infarction, Cerebral Hemorrhage, PrognosisAbstract
Standardizated criteria for predicting hemorrhagic transformation of cerebral infarction are currently absent.
Aim. With the aim to determine predictors of hemorrhagic transformation of hemispheric cerebral infarction and its influence on the outcome of the acute period of disease clinical and paraclinical examination of 135 patients with acute cerebral ischemic supratentorial stroke was done.
Methods and results. It was detected that the combination of atrial fibrillation and type 2 diabetes were associated with increased risk of hemorrhagic transformation. A mathematical model for hemorrhagic transformation predicting was elaborated. It takes into account the value of the total score according to the National Institutes of Health in the onset of the disease, blood glucose levels in admission period and the volume of the lesion.
Conclusion. It was proved that parenchymal hematoma is criteria of unfavorable vital outcome prognosis of the acute period of cerebral supratentorial ischemic stroke.
References
Jauch, E. C., Saver, J. L., Adams, H. P., Bruno, A., Connors, J. J., Demaerschalk, B. M., et al. (2013). AHA/ASA Guideline for the Early Management of Patients With Acute Ischemic Stroke. Stroke, 44, 870–947. doi: 10.1161/STR.0b013e318284056a.
Alpert, J. C., Calcins, H., Cleveland, J. C., Calkins, H., Cigarroa, J. E., Cleveland, J. C., et al. (2014). AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation. Circulation, 130(23), 2071–2104. doi: 10.1161/CIR.0000000000000040.
Bang, O. Y., Saver, J. L., Kim, S. J., Kim, G. M., Chung, C. S., Ovbiagele, B., et al. (2011). Collateral flow averts hemorrhagic transformation after endovascular therapy for acute ischemic stroke. Stroke, 42, 2235–2239. doi: 10.1161/STROKEAHA.110.604603.
Tan, S., Wang, D., Liu, M., Zhang, S., Wu, B., & Liu, B. (2014). Frequency and predictors of spontaneous hemorrhagic transformation in ischemic stroke and its association with prognosis. J Neurol, 261, 905–912. doi: 10.1007/s00415-014-7297-8.
Jaillard, A., Cornu, C., Durieux, A., Moulin, T., Boutitie, F., Lees, K.R., & Hommel, M. (1999). Hemorrhagic transformation in acute ischemic stroke. The MAST-E study. MAST-E Group. Stroke, 30, 1326–1332. doi: 10.1161/01.STR.30.7.1326.
Zhang, J., Yang, Y., Sun, H., & Xing, Y. (2014). Hemorrhagic transformation after cerebral infarction: current concepts and challenges. Ann Transl Med, 2(8), 81. doi: 10.3978/j.issn.2305-5839.2014.08.08.
Mukherjee, D., & Patil, C. G. (2011). Epidemiology and the global burden of stroke. World Neurosurgery, 76(6), 85–90. doi: 10.1016/j.wneu.2011.07.023.
Nogueira, R. G., Gupta, R., Jovin, T. G., Levy, E. I., Liebeskind, D. S, Zaidat, O. O., et al. (2015). Predictors and clinical relevance of hemorrhagic transformation after endovascular therapy for anterior circulation large vessel occlusion strokes: a multicenter retrospective analysis of 1122 patients. J Neurointerv Surg, 7(1), 16–21. doi: 10.1136/neurintsurg-2013-010743.
Larrue, V., von Kummer, R., Müller, A., & Bluhmki, E. (2001). Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS II). Stroke, 32(2), 438–441. doi: 10.1161/01.STR.32.2.438.
(2011). The Top Ten Causes of Death. Fact Sheet № 310, Geneva, World Health Organization.
Downloads
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)
