DOI: https://doi.org/10.14739/2310-1210.2015.3.44511

Возможности статинов в предупреждении прогрессирования хронических диффузных заболеваний почек

V. V. Syvolap, M. P. Gerasko

Аннотация


В последнее время в научной литературе появляются противоречивые данные в отношении целесообразности назначения статинов при ХЗП. С целью определения перспектив использования статинов в профилактике и лечении хронических диффузных заболеваний почек методами углублённого литературного обзора изучены результаты международных многоцентровых рандомизированных исследований сравнительной эффективности различных препаратов данного класса. В обзоре показаны плейотропные эффекты, профиль безопасности и переносимости, преимущества отдельных представителей данного класса препаратов у пациентов с почечной патологией. Проведенные исследования свидетельствуют: хронические заболевания почек не являются противопоказанием для назначения статинов.


Ключевые слова


дислипидемия; скорость клубочковой фильтрации; заболевания почек; лечение

Полный текст:

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Литература


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