Structural and functional condition of the left ventricle and the arterial wall stiffness in patients with essential hypertension
DOI:
https://doi.org/10.14739/2310-1210.2015.4.50252Keywords:
Hypertension, Pulse Wave Velocity, Aortic Pressure, Left Ventricular HypertrophyAbstract
Impact of the left ventricular hypertrophy (LVH) and increasing of the pulse wave velocity in aorta (PWV) at cardiovascular risk proved in various groups of patients.
Aim. The aim of the study was to investigate the features of the myocardial structural and functional conditions and the arterial wall stiffness, as well as their relationship to male patients with essential hypertension (EH) I-II stage.
Materials and methods. 53 male patients with essential hypertension stage I and II, aged 30–67 years were surveyed. All patients underwent clinical and laboratory examination in accordance with Ukrainian National Guidelines and ESH/ESC Guidelines for the management of arterial hypertension (2013). Echocardiography was performed in B- and M-modes. Elastic properties of the arterial wall were investigated with Arteriograph TensioMed (TensioClinic, Hungary).
Conclusions. At the male patients with essential hypertension PWV was associated with increasing of LVM, LVMI, LVMI/h1,7 and LVMI/h2,7 by increased SWTat stage of the left ventricular hypertrophy formation. cSBP and cPP increase makes a significant contribution to the process of the heart remodeling in hypertensive patients with LVH. cPP increase contribute to LA size enlargement and LV systolic function reduce in patients with EH and LVH.
References
Levy, D., Garrison, R. J., Savage, D. D., Kannel, W. B., & Castelli, W. P. (1990). Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. The New England Journal of Medicine, 322(22), 1561–1566. doi: 10.1056/NEJM199005313222203.
Verdecchia, P., Schillaci, G., Borgioni, C., Ciucci, A., Gattobigio, R., Zampi, I., & Porcellati, C. (1998). Prognostic value of a new electrocardiographic method for diagnosis of left ventricular hypertrophy in essential hypertension. Journal of the American College of Cardiology, 31(2), 383–390. doi:10.1016/S0735-1097(97)00493-2.
Mancia, G., De Backer, G., Dominiczak, A., Cifkova, R., Fagard, R., Germano, G.,
et al. (2007). 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Journal of Hypertension, 25(6), 1105–1187. http://doi.org/10.1097/HJH.0b013e3281fc975a.
Members, A. F., Perk, J., Backer, G. D., Gohlke, H., Graham, I., Reiner, Ž., et al. (2012). European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). European Heart Journal, 33(17), 1635–1701. doi: 10.1093/eurheartj/ehs092.
Mancia, G., Fagard, R., Narkiewicz, K., Redon, J., Zanchetti, A., Böhm, M., et al. (2013). 2013 ESH/ESC Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 34(28), 2159–2219. doi: 10.1093/eurheartj/eht151.
(2012) Unifikovanyi klinichnyi protokol pervynnoi, ekstrenoi ta vtorynnoi (spetsializovanoi) medychnoi dopomohy “Arterialna hipertenziia”. [in Ukrainin].
Matsushita, K., Mahmoodi, B. K., Woodward, M., Emberson, J. R., Jafar, T. H., Jee, S. H., et al. (2012). Comparison of risk prediction using the CKD-EPI equation and the MDRD Study equation for estimated glomerular filtration rate. JAMA, 307(18). doi: 10.1001/jama.2012.3954.
Johansen, N. B., Vistisen, D., Brunner, E. J., Tabák, A. G., Shipley, M. J., Wilkinson, I. B., et al. (2012). Determinants of Aortic Stiffness: 16-Year Follow-Up of the Whitehall II Study. PLoS ONE, 7(5), e37165. doi: 10.1371/journal.pone.0037165.
Lang, R. M., Bierig, M., Devereux, R. B., Flachskampf, F. A., Foster, E., Pellikka, P. A., et al. (2006). Recommendations for chamber quantification. European Heart Journal - Cardiovascular Imaging, 7(2), 79–108. doi:10.1016/j.euje.2005.12.014.
Chirinos, J. A., Segers, P., Buyzere, M. L. D., Kronmal, R. A., Raja, M. W., Bacquer, D. D., et al. (2010). Left Ventricular Mass Allometric Scaling, Normative Values, Effect of Obesity, and Prognostic Performance. Hypertension, 56(1), 91–98. doi: 10.1161/HYPERTENSIONAHA.110.150250.
Armstrong, A. C., Gidding, S., Gjesdal, O., Wu, C., Bluemke, D. A., & Lima, J. A. (2012). LVM Assessed by Echocardiography and Cardiac Magnetic Resonance, Cardiovascular Outcomes, and Medical Practice. JACC. Cardiovascular Imaging, 5(8), 837–848. doi: 10.1016/j.jcmg.2012.06.003.
Roman, M. J., Devereux, R. B., Kizer, J. R., Lee, E. T., Galloway, J. M., Ali, T. et al. (2007). Central Pressure More Strongly Relates to Vascular Disease and Outcome Than Does Brachial Pressure The Strong Heart Study. Hypertension, 50(1), 197–203. doi: 10.1161/HYPERTENSIONAHA.107.089078.
Vlachopoulos, C., Aznaouridis, K., O’Rourke, M. F., Safar, M. E., Baou, K., & Stefanadis, C. (2010). Prediction of cardiovascular events and all-cause mortality with central haemodynamics: a systematic review and meta-analysis. European Heart Journal, 31(15), 1865–1871. doi:10.1093/eurheartj/ehq024.
Schillaci, G., Mannarino, M. R., Pucci, G., Pirro, M., Helou, J., Savarese, G., Mannarino, E., et al. (2007). Age-Specific Relationship of Aortic Pulse Wave Velocity With Left Ventricular Geometry and Function in. Hypertension, 49(2), 317–321. doi:10.1161/01.HYP.0000255790.98391.9b.
KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. (2013). Kidney Int (Suppl.), 3.
Roman, M. J., Okin, P. M., Kizer, J. R., Lee, E. T., Howard, B. V., & Devereux, R. B. (2010). Relations of central and brachial blood pressure to left ventricular hypertrophy and geometry: the Strong Heart Study. Journal of Hypertension, 28(2), 384–388. doi: 10.1097/HJH.0b013e328333d228.
Andrikou, E., Tsioufis, C., Dimitriadis, K., Flessas, D., Chatzistamatiou, V., Grassos, C., et al. (2011). Parallel deterioration of albuminuria, arterial stiffness and left ventricular mass in essential hypertension: integrating target organ damage. Nephron. Clinical Practice, 119(1), 27–34. doi: 10.1159/000324215.
Bell, V., Sigurdsson, S., Westenberg, J. J. M., Gotal, J. D., Torjesen, A. A., Aspelund, T., et al. (2015). Relations between aortic stiffness and left ventricular structure and function in older participants in the age, gene/environment susceptibility--Reykjavik Study. Circulation. Cardiovascular Imaging, 8(4), e003039. doi: 10.1161/CIRCIMAGING.114.003039.
Wang, K.-L., Cheng, H.-M., Chuang, S.-Y., Spurgeon, H. A., Ting, C.-T., Lakatta, E. G., et al. (2009). Central or peripheral systolic or pulse pressure: which best relates to target-organs and future mortality? Journal of Hypertension, 27(3), 461–467.
Downloads
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)
