Integrated differentiated therapy of patients with relapses of rosacea taking into account heart rate variability indices and psychological status changes

Authors

  • A. V. Vasilenko

DOI:

https://doi.org/10.14739/2310-1210.2015.4.50255

Keywords:

Rosacea, Relapses, Pathogenesis, Treatment, Nervous System

Abstract

Aim. To develop modern methods of complex differential treatment, prognosis and prevention of development of relapses of rosacea.

Methods and results. We examined 50 patients with this dermatosis. Complex clinical data, state of the autonomic nervous system (ANS) and changes in the psychological status were studied. Autonomic dysfunction was determined by the method of computer electrocardiography. Psychometric evaluation was conducted by the evaluation scales and questionnaires. The effectiveness of the developed method of treatment was evaluated by clinical manifestations and indicators research. It was found that the imbalance of the ANS and emotional disorders are more prominent in patients with relapses of rosacea. Proposed therapy plan leads to the more rapid regression of symptoms and persistent positive result.

Conclusions. Еarly diagnosis of changes in the ANS allows to predict the course of disease and to increase the effectiveness of treatment of relapses of rosacea.

References

Bitkina, О. А., & Nikulin, N. К. (2010). Etiologiya i patogenez rozacea. Voprosy diferencialnogo diagnoza i terapii [The etiology and pathogenesis of rosacea. Issues of differential diagnosis and therapy]. Rossijskij zhurnal kozhnykh i venericheskikh boleznej, 1, 54–57. [in Russian].

Volkova, E. N., Osipova, N. K., Rodina, U. A., & Grigoreva, A. A. (2010). Rozacea: novye podkhody k starym problemam [Rosacea: new approaches to old problems]. Rossijskij zhurnal kozhnykh i venericheskikh boleznej, 2, 33–36. [in Russian].

Kaliuzhna, L. D., & Bardova, K. O. (2012). Mozhlyvist zastosuvannia preparativ metronidazolu v likuvanni rozatsea ta perioralnoho dermatytu, poiednanykh z demodekozom [The possibility of application of preparations of metronidazole in treatment of rosacea and perioral dermatitis, United demodicosis]. Ukrainskyi zhurnal dermatolohii, venerolohii, kosmetolohii, 4, 42–46. [in Ukrainian].

Katkhanova, O. A., Levchenko, N. U., & Anikienko, O. V. (2012). E′tiopatologicheskie aspekty rosacea, vozmozhnosti terapii [Etiopathogenetic aspects of rosacea, treatment options]. Dal′nevostochnyi vestnik dermatovenerologii kosmetologii i plasticheskoj khirurgii, 1, 11–12. [in Russian].

Kogan, B. G. (2012). Sovremennye podkhody v kompleksnom lechenii pacientov s demodicozom i rozovymi ugryami [Modern approaches in treatment of patients with Demodex mange. and pink acne]. Ukrainskij zhurnal dermatologii, venerologii, kosmetologii, 4, 55–62. [in Ukrainian].

Protsenko, T. V., & Andriichuk, V. B. (2012). Efektyvnist aerokrioterapii u kompleksnomu likuvanni khvorykh iz rannimy piznimy ta rozhevymy akne [The effectiveness of Aero-cryo-therapy in treatment of early, late and pink acne]. Dermatolohia ta venerolohia, 1, 79–84. [in Ukrainian].

Elewski, B. E., Draelos, Z., Drеno, B., Jansen, T., Layton, A., & Picardo, M. (2011). Rosacea – global diversity and optimized outcome: proposed international consensus from the Rosacea International Expert Group. J. Eur. Acad. Dermatology venerology, 25, 188–200. doi: 10.1111/j.1468-3083.2010.03751.x.

Serdar, Z. A., & Yaşar, Ş. (2011). Effi cacy of 1% terbinafi ne cream in comparison with 0.75% metronidazole gel for the treatment of papulopustular rosacea. Cutan Ocul Toxicoloji, 30, 124–128. doi: 10.3109/15569527.2010.541398.

Van Zuuren, E. J., Kramer, S. F., Carter, B. R., Graber, M. A., & Fedorowicz, Z. (2011). Effective and evidence based management strategies for rosacea: summary of a Cochrane systematic review. Brit. J. Dermatology, 165, 760–781. doi: 10.1111/j.1365-2133.2011.10473.x.

How to Cite

1.
Vasilenko AV. Integrated differentiated therapy of patients with relapses of rosacea taking into account heart rate variability indices and psychological status changes. Zaporozhye Medical Journal [Internet]. 2015Sep.16 [cited 2024Nov.5];17(4). Available from: http://zmj.zsmu.edu.ua/article/view/50255

Issue

Section

Original research