Relationship of the anxiety-depressive disorder with coronary heart disease, comorbid with metabolic syndrome
DOI:
https://doi.org/10.14739/2310-1210.2015.5.53743Keywords:
Anxiety-Depressive Disorders, Coronary Heart Disease, Metabolic SyndromeAbstract
Aim. It is expected that combination of anxiety and depressive disorders with components of the metabolic syndrome can summarize their effects that can significantly affect the prognosis of patients with coronary heart disease.
Methods and results. In order to establish an interconnections of the anxiety and depressive disorders with components of the metabolic syndrome in patients with coronary artery disease and to assess their impact on the course of the disease 81 patients with a diagnosis of coronary heart disease: angina pectoris II-III functional class were examined. The 1st group consisted of the 35 patients with isolated coronary heart disease, group 2 - 46 patients with coronary heart disease and metabolic syndrome. With the help of clinical and biochemical analysis, daily ECG monitoring, Seattle Angina Questionnaire, SF-36 questionnaire, the Hospital Anxiety and Depression Scale HADS we investigated the severity of anxiety and depression and life quality of the patients , depending on higher overall levels of anxiety and depression on the scale of HADS.
Conclusion. It was found that for coronary heart disease concomitant with the metabolic syndrome is associated with higher overall levels of anxiety and depression on the scale of HADS, correlated with components of metabolic syndrome such as abdominal obesity, dyslipidemia and hyperglycemia. The presence of anxiety and depressive disorders in patients with metabolic syndrome, accompanied by more severe clinical course coronary heart disease according to Seattle questionnaire, reduced quality of life for patients, an imbalance of the autonomic nervous system in the direction of increased activity of the sympathetic part.
References
Lutaj, M. I., Lysenko, A. F., & Golikova, I. P. (2013) Diagnostika i lechenie stabil'noj stenokardii v Ukraine: problemy i perspektivy [Diagnosis and treatment of stable angina in Ukraine: problems and prospects]. Proceedings of the National Congress of Cardiologists of Ukraine, 119–126. [in Ukrainian].
Dickens, C.M., McGowan, L., Percival, C., Douglas, J., Tomenson, B., Cotter, L., et al. (2004) Lack of a close confidant, but not depression, predicts further cardiac events after myocardial infarction. Heart, 90, 518–522. doi: 10.1136/hrt.2003.011668.
Berkman, L., Jaffe, A., Carney, R., Czajkowski, S., Kaufman, P., Blumenthal, J.A., et al. (2001) Enhancing Recovery in Coronary Heart Disease study intervention: rationale and design. Psychosomatic Medicine, 63, 747–755.
Nemeroff, C. B., & Musselman, D. L. (2000) Are platelets the link between depression and ischemic heart disease? Am Heart J., 140, 57–62.
Drobizhev, M. Yu. (2003) Lechenie depressij v obschesomaticheskoj seti [Treatment of depression in somatic]. Psikhiatriya i psikhofarmakoterapiya, 5, 8–12. [in Russian].
Mitchenko, E. I., Mamedov, M. N., Kolesnik, T. V., & Deev, A. D. (2013) Sovremennyj profil' faktorov riska serdechno-sosudistykh zabolevanij v gorodskoj populyacii Ukrainy [The modern profile of risk factors for cardiovascular diseases in the urban population of Ukraine]. Proceedings of the 14th National Congress of Cardiologists of Ukraine, 76. [in Ukraine].
Zigmond, A. C., & Snaith, R. P. (1983) The Hospital Anxiety and Depression scale. Acta Psychiatr. Scand., 67, 361–337.
Oganov, R. G. (2004) Sochetanie komponentov metabolicheskogo sindroma svyazano s vysokim riskom ateroskleroticheskikh zabolevanij [The combination of the components of the metabolic syndrome is associated with a high risk of atherosclerotic diseases]. Kardiovaskulyarnaya terapiya i profilaktika, 1, 56–59. [in Russian].
Ozdoev, L. D. (2003) Vzaimosvjaz' faktorov riska ateroskleroza i trevozhno-depressivnykh sostoyanij u muzhchin iz neorganizovannoj populyacii [The relationship of risk factors of atherosclerosis and anxiety and depression in men from unorganized population]. Kardiovaskulyarnaya terapiya i profilaktika, 2(1), 59–64. [in Russian].
Poghosova, G. V. (2002) Depressiya u bol'nykh ishemicheskoj bolezn'yu serdca i novye vozmozhnosti eyo lecheniya [Depression in patients with coronary heart disease and new opportunities for its treatment]. Psikhiatriya i psikhofarmakoterapiya, 4(5), 195–198. [in Russian].
Prokhorenko, I. O., Zarubina, E. G., & Moiseeva, T. V. (2012) Vliyanie depressii na formirovanie metabolicheskogo sindroma i razvitie IBS u pacientov starshikh vozrastnykh grupp [The influence of depression on metabolic syndrome and ihd development at patients of senior age groups]. Sovremennye problemy nauki i obrazovaniya, 6, 214. [in Russian].
Kaliuzhin, V. V., Tepliakov, A. T., Riazantseva, N. V., Bespalova, I. D., Kamaev, D. Iu., & Kaliuzhina, E. V. (2012) Kachestvo zhizni bol'nykh ishemicheskoj bolezn'yu serdca, associirovannoj s metabolicheskim sindromom: rezul'taty faktornogo analiza [Quality of life in patients with coronary heart disease associated with metabolic syndrome: Results of factor analysis]. Terapevticheskij arhiv, 12, 20–21. [in Russian].
Mikhаjlichenko, T. M. (2008) Struktura emocional′nykh narushenij i mekhanizmov adaptacii k bolezni u pacientov s nealkogol′noj zhirovoj bolezn′yu pecheni v ramkakh metabolicheskogo sindroma (v svyazi s zadachami psikhoterapii) (Dis… kand. psihkol. nauk). [The structure of emotional disorders and mechanisms of adaptation to the disease in patients with nonalcoholic fatty liver disease as part of the metabolic syndrome (in connection with the objectives of psychotherapy) Dr. med. sci. diss.]. Saint Petersburg. [in Russian].
Dolzhenko, M. N. (2013). Depressivnye i trevozhnye rasstrojstva v kardiologii: vozmozhnost' kombinirovannoj terapii antidepresantom i antigipoksantom [Depressive and anxiety disorders in cardiology: the possibility of combination therapy and antidepressants antihypoxant]. Novosti mediciny i farmacii, 18, 45–46. [in Ukrainian].
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