Age-related changes in the structural parameters of the heart and myocardial remodeling in chronic heart failure in women with overweight and obesity
DOI:
https://doi.org/10.14739/2310-1210.2015.5.53769Keywords:
Heart Failure, Women, Obesity, Ventricular Remodeling, Age FactorsAbstract
According to different authors, the representation of women in the structure of chronic heart failure (CHF) ranges from 50% to 60%, however, in clinical studies the number of participants in the female reaches only 20–30%.
Aim. To study age-related changes in the structural parameters of the heart and myocardial remodeling in CHF. 216 women of different age groups who have had CHF I–III functional class on the background of normal, overweight and abdominal obesity I–III degree were examined.
Methods and results. Structural parameters of the heart and the condition of cardiac remodeling were estimated with echocardiography. Found that in CHF in women with overweight and obesity with age increasing is a more significant dilatation of cardiac chambers, myocardial hypertrophy of the left ventricle and the calcination of valve apparatus. In most cases myocardial remodeling were presented by concentric hypertrophy of the left ventricle.
Conclusion. This demonstrates negative impact of increasing age on the restructuring of the heart in conditions of CHF in women with overweight and obesity.
References
Heidenreich, P. A., Trogdon, J. G., Khavjou, O. A., Butler, J., Dracup, K., Ezekowitz, M.D., et al. (2011) Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation, 123(8), 933–944. doi: 10.1161/CIR.0b013e31820a55f5.
Lishnevskaya, V. Yu. (2010) Osobenosti lecheniya khronicheskoj serdechnoj nedostatochnosti u lic pozhilogo vozrasta [Features of treatment of chronic heart failure in the elderly]. Ukrainskyi medychnyi chasopys, 6(80), 87–93. [in Ukrainian].
Cowie, Mr., Fox, K.F., Wood, D.A., Metcalfe, C., Thompson, S.G., Coats, A. J., et al. (2002) Hospitalization of patients with heart failure: a population-based study. Tur. Heart J., 23(11), 877–885. doi:10.1053/euhj.2001.2973.
Shah, R.U., Chang, T., & Fonarow, G.C. (2013) Comparative Effectiveness Research in Heart Failure Therapies Women, Elderly Patients, and Patients with Kidney Disease. Heart Fail. Clin., 9(1), 79–92. doi: 10.1016/j.hfc.2012.09.003.
Heiat, A., Gross, C. P., & Krumholz, H. M. (2002) Representation of the elderly, women, and minorities in heart failure clinical trials. Arch. Intern. Med., 162(15), 1682–8. doi: 10.1001/archinte.162.15.1682.
Chen, Y. T., Vaccarino, V., Williams, C. S., Butler, J., Berkman, L. F., & Krumholz, H. M. (1999) Risk factors for heart failure in the elderly: a prospective community-based study. Am. J. Med., 106, 605–612. doi:10.1016/S0002-9343(99)00126-6.
Kenchaiah, S., Evans, J. C., Levy, D., Wilson, P. W., Benjamin, E. J., Larson, M. G., et al. (2002). Obesity and the risk of heart failure. N. Engl. J. Med., 347, 305–313. doi: 10.1056/NEJMoa020245.
Hubert, H. B., Feinleib M., McNamara, P., & Castelli, W. P. (1983). Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham study. Circulation, 67, 968–977. doi: 10.1161/01.CIR.67.5.968.
Klabnik, A., & Murin, Ya. (2013). Khronichna sertseva nedostatnist u zhinok: korotkyi ohliad z aktsentom na novykh markerakh yakosti terapii [Chronic heart failure in women: short review with accent on new markers of quality of therapy]. Liky Ukrainy, 7(173), 80–83. [in Ukrainian].
Voronkov, L. H., et al. (2013). Rekomendacii po diagnostike i lecheniyu khronicheskoj serdechnoj nedostatochnosti (2012) [Guidelines for the diagnosis and treatment of chronic heart failure (2012)]. Ukrainskij kardiologicheskij zhurnal, 1, 6–44. [in Ukrainian].
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