An Importance of Magnesium Deficiency in the Formation of Vegetative Disadaptation in Children and Adolescents with Digestive Tract Pathology
DOI:
https://doi.org/10.14739/2310-1210.2015.6.56281Keywords:
Digestive Tract Pathology, Magnesium Deficiency, Children, AdolescentsAbstract
Aim. In the study of magnesium deficiency, a distinction is made between magnesium hypoelementosis and magnesium deficit. As a result, detection of the magnesium deficiency and its influence on vegetative disadaptation progression can help to correct damages in early stages and to decrease frequency of chronization of digestive tract disorders in children.
Methods and results. 48 children at the ages from 7 to 17 years with complaints on sickliness, stomachache, dyspeptic symptoms were under the care. The first group contained of 28 children with organic digestive system disorders, the second – 20 children with functional digestive system disorders. In both groups serum and intracellular concentration of Mg, Holter monitoring of ECG were carried out.
Conclusion. Among children and adolescents with digestive tract pathology, 4,3% of patients had magnesium deficit. Hypoelementosis was detected in 18,7% of cases, that demonstrates great prevalence of latent magnesium deficiency and the necessity of the intracellular content study. Indices of both intracellular (p≤0,05) and extracellular (p ≤0,001) magnesium in children from the 1st group were much lower than in children from the 2nd group. This demonstrates mutual influence of organic digestive tract pathology and magnesium deficit on the development and severity of pathologies. Direct and strong correlation line between intracellular magnesium level lowering and lowered indices of HRV time-line analysis was detected in the 1st group. Correlation absence in the 2nd group demonstrates the influence of magnesium deficiency on vegetative disadaptation development and provides change of digestive tract functional disorders to organic.
References
Shilov, A. M. (2013). Rol' deficita magniya v serdechno-sosudistom kontinuume [Magnesium Deficiency and Cardiovascular Continuum]. Lechebnoe delo, 4, 73–82. [in Russian].
Gromova, O. A., & Torshin, I. Yu. (2014). Magnij i piridoksin, osnovy znanij [Magnesium and pyridoxine, basic knowledge]. Moscow. [in Russian].
Kalacheva, A. G. (2011). Element-specificheskie indikatory nejrotropnykh funkcij magniya (Avtoref. dis…kand. med. nauk). [Element-specific indicators neurotrophic functions of magnesium]. (Extended abstract of candidate’s thesis).Moscow. [in Russian].
Gromova, O. A., Torshin, I. Yu., Volkova, A. Yu., & Nosikov, V. V. (2014). Normativy pri diagnostike deficita magniya v razlichnykh biosubstratakh [Standards for diagnosis of magnesium deficiency in various biosubstrates]. Medicinskij alfavit, 2(12), 34–43. [in Russian].
Kozlovsky, A. A. (2013). Gipokalemiya i gipomagniemiya i ikh korrekciya u detej i podrostkov [Hypokaleimia and hypomagnesemia and their correction in children and adolescents]. Mezhdunarodnye obzory: klinicheskaya praktika i zdorov′e, 2(2), 34–48. [in Russian].
Vanaelst, B., Huybrechts, I., Michels, N., Flórez, M., Aramendía, M., Balcaen, L., et al. (2012). Hair Minerals and Metabolic Health in Belgian Elementary School Girls. Biological Trace Element Research, 151(3), 335–343. doi: 10.1007/s12011-012-9573-8.
Morales-Ruán, M., Villalpando, S., García-Guerra, A., Shamah-Levy, T., Robledo-Pérez, R., Ávila-Arcos, M., & Rivera, J. (2012). Iron, zinc, copper and magnesium nutritional status in Mexican children aged 1 to 11 years. Salud pública Méx, 54(2), 125–134.
Panhwar, A., Kazi, T., Afridi, H., Shaikh, H., Arain, S., Arain, S., & Brahman, K. (2013). Evaluation of Calcium and Magnesium in Scalp Hair Samples of Population Consuming Different Drinking Water: Risk of Kidney Stone. Biological Trace Element Research, 156(1–3), 67–73. doi: 10.1007/s12011-013-9850-1.
Khan, A., Lubitz, S., Sullivan, L., Sun, J., Levy, D., Vasan, R., et al. (2012). Low Serum Magnesium and the Development of Atrial Fibrillation in the Community: The Framingham Heart Study. Circulation, 127(1), 33–38. doi: 10.1161/CIRCULATIONAHA.111.082511.
Downloads
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)