Changes in heart rate variability in patients with hypertension under outpatient stage treatment

Authors

  • V. I. Koshlia SE «Zaporizhzhia Medical Academy of Postgraduate Education of MOH Ukraine»,
  • Mouna Ben-Abid SE «Zaporizhzhia Medical Academy of Postgraduate Education of MOH Ukraine»,

DOI:

https://doi.org/10.14739/2310-1210.2015.6.56305

Keywords:

Arterial Hypertension, Heart Rate, Telmisartan, Bisoprolol

Abstract

Actuality of the heart rate variability study in patients with hypertension is underlined with high risk of hypertension complications development and the influence of the autonomic nervous system that changes the tone, affects not only the course of the disease but also increases the risk of death.

The aim was to study heart rate variability with conventional methods, in order to increase the efficiency of the hypertension treatment with telmisartan and bisoprolol in 35 patients suffering from high blood pressure with degree I and II in an ambulatory care clinic.

Results. It has been proven that the treatment with bisoprolol and telmisartan in patients with hypertension degree I and II is accompanied by a significant reduction of the sympathetic division activity of the autonomic nervous system, indicating positive change of the autonomic imbalance and increased activity of the parasympathetic system, therefore accompanied by significant reduction in the low frequency spectrum of the sympathetic nervous system in relation with the cardiac activity and the confirmed indicators LF / HF.

References

Vasyleva A.D. (2008) Blokatory angiotenzinovykh receptorov v lechenii arterial'noj gipertonii [Angiotensin receptor blockers in the treatment of hypertension]. Russkij medicinskij zhurnal, 16(5), 289–292. [in Russian].

Vasyuk, Yu. A. (2007) Beta-blokatory pri arterial'noj gipertenzii: konec e′ry vsego klassa ili ten' na pleten'? [Beta-blockers in hypertension: end of an era of the whole class, or shadow on the fence?]. Trudnyj pacient, 8, 23–29. [in Russian].

Vlasova, T. V. (2006) Arterial'naya gipertenziya v ambulatornoj klinicheskoj praktike: diagnostika i taktika vedeniya, bol'nykh [Arterial hypertension in ambulatory clinical practice: Diagnosis and tactics of patients]. Nizhnij Novgorod. [in Russian].

Drapkina, O. M. (2008) Antagonisty angiotenzinovykh receptorov v lechenii serdechno-sosudistykh zabolevanij [Angiotensin receptor antagonists in treating cardiovascular diseases]. Spravochnik poliklinicheskogo vracha, 5, 22–24. [in Russian].

Korkushko, O. V., Pisarchuk, A. V., & Shatylo, V. B., et al. (2012) Analiz variabel'nosti ritma serdca v klinicheskoj praktike [Analysis of heart rate variability in clinical practice]. Kyiv. [in Russian].

Shilov, A. M. (2010) Deficit magniya i arterial'naya gipertoniya [Magnesium deficiency and hypertension]. Rossijskie medicinskie vesti, 5(2), 62–65. [in Russian].

Ivanova, O. V. (2012) Blokator receptorov angiotenizina II telmisartan: vliyanie na sutochnyj profil' arterial'nogo davleniya i gipertrofiyu miokarda levogo zheludochka u bol'nykh arterial'noj gipertoniej [Angiotensin II receptor antagonist telmisartan: impact on daily blood pressure and left ventricular hypertrophy in hypertensive patients]. Kardiologiya, 2, 45–49. [in Russian].

Benson, S. C. (2014) Identification of telmisartan as a unique angiotensin II: receptor antagonist with selective PPARgamma.-modulating activity. Hypertension, 1(43), 993–1002.

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How to Cite

1.
Koshlia VI, Ben-Abid M. Changes in heart rate variability in patients with hypertension under outpatient stage treatment. Zaporozhye Medical Journal [Internet]. 2015Dec.29 [cited 2024Nov.27];17(6). Available from: http://zmj.zsmu.edu.ua/article/view/56305

Issue

No. 6 (2015): Zaporozhye medical journal

Section

Original research

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