Assessment of renal dysfunction in patients with cirrhosis

Authors

  • A. S. Tugushev Zaporizhzhia State Medical University,
  • A. V. Bolgova SD «Local Clinical Hospital on the Station Zaporizhzhia-2 of the Pridneprovsky Railway»,
  • T. V. Ermakova SD «Local Clinical Hospital on the Station Zaporizhzhia-2 of the Pridneprovsky Railway»,
  • D. A. Nosov SD «Local Clinical Hospital on the Station Zaporizhzhia-2 of the Pridneprovsky Railway»,
  • L. A. Chubich Zaporizhzhia Regional Psychiatric Hospital,

DOI:

https://doi.org/10.14739/2310-1210.2015.6.57046

Keywords:

Cirrhosis, Kidney Diseases, Creatinine, Cystatin C, Glomerular Filtration Rate

Abstract

Emergence of renal dysfunction in cirrhosis is an integral part of a natural course of the disease characterizing its weight. In turn, development of renal dysfunction is considered one of the pathogenetic moments of development of the main complications of cirrhosis. Thus principles of diagnostics of renal dysfunction fully are not defined today.

Aim. For the purpose of an assessment of diagnostic importance of laboratory criteria violation of secretory function of kidneys in patients with the complicated course of cirrhosis we investigated kidneys function in 120 patients with decompensated cirrhosis depending on positive or negative result of treatment.

Methods and results. Laboratory researches included definition of a creatinine, sodium and potassium in blood and urine, glomerular filtration rate (GFR), clearance of an endogenous creatinine and serum cystatin C level. It is established that serum cystatin C level is the most informative criterion of assessment of the renal dysfunction and it can be used as a criterion of efficiency of treatment and prognosis of the clinical course.

Conclusion. This indicates the importance of renal dysfunction in development of cirrhosis complications .

References

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How to Cite

1.
Tugushev AS, Bolgova AV, Ermakova TV, Nosov DA, Chubich LA. Assessment of renal dysfunction in patients with cirrhosis. Zaporozhye Medical Journal [Internet]. 2015Dec.29 [cited 2024Oct.16];17(6). Available from: http://zmj.zsmu.edu.ua/article/view/57046

Issue

No. 6 (2015): Zaporozhye medical journal

Section

Original research

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