The prevalence of obesity in patients with non-valvular persistent atrial fibrillation during long observations

Authors

  • K. O. Pysarevska Dnipropetrovsk Medical Academy,

DOI:

https://doi.org/10.14739/2310-1210.2016.2.69171

Keywords:

Atrial Fibrillation, Body Mass Index, Obesity

Abstract

Аim: to study the prevalence of obesity in patients with non-valvular persistent atrial fibrillation (AF) who underwent electrical cardioversion (ECV) in Municipal Institution of Dnipropetrovsk regional council Dnipropetrovsk regional clinical center of cardiology and cardiac surgery.

Methods and results. 104 patients (mean age 63.2±0.4 years) with non-valvular persistent AF were included in the study. The average duration of a history of arrhythmia was 3.0±0.3 years. AF was associated with arterial hypertension (76.9%) and coronary artery disease (22.1%), 13.4% of patients had no cardiac disease. Transthoracic echocardiography (TTE) was held according to ASA recommendations before ECV.

Conclusion: obesity as a comorbid condition was diagnosed in 61% of patients with non-valvular persistent AF. Only 10% of patients had normal body weight. Most people were obese class I (33.8%) and class II (17.9%). Body mass index (BMI) above 40 kg/m2 was in 9.5% of patients. BMI is directly correlated with the level of diastolic blood pressure (r=0.35; p<0,001) and echocardiographic parameters that indicated ventricular hypertrophy: left ventricular mass (r=0,4; p<0,001), interventricular septum thickness (r=0.41; p<0.001) and left ventricular (LV) posterior wall thickness (r=0.4; p<0.001). Patients with persistent non-valvular AF and obesity need to reduce the body mass index.

References

Chugh S. S., Havmoeller R., Narayanan K., Singh D., Rienstra M., Benjamin E. J., Gillum R. F., Kim Y. H., McAnulty J. H. Jr., Zheng Z. J., Forouzanfar M. H., Naghavi M., Mensah G. A., Ezzati M., Murray C. J. Worldwide epidemiology of atrial fibrillation: a global burden of disease 2010 study. Circulation 2014;129:837–847.

World Health Organization Mc. Obesity and overweight fact sheet no 311. January 2015. www.who.int/mediacentre/factsheets/fs311/en/.

The statistical collections of the State Statistics Service of Ukraine. - 2012.

Drapkina, O. M., Korneev, O. M. & Palatkin, L. O. (2011). Adipokines and cardiovascular disease: pathogenetic parallels therapeutic perspectives. Hypertension, 17(3), 203-208.

Druzhilov, M. A., Druzhilova, O., Beteleva, Y. E. & Kuznetsova T. Yu. (2015). Obesity as a factor of cardiovascular risk: focus on quality and the functional activity of adipose tissue. Russian J. of Cardiol., 4(120),111-117.

Nalliah C. J., Sanders P., Kottkamp H., Kalman J. M. The role of obesity in atrial fibrillation. European Heart Journal 2015; doi:10.1093/eurheartj/ehv486

Guglin M., Maradia K., Ren Chen, Curtis A. B. Relation of Obesity to Recurrence Rate and Burden of Atrial Fibrillation. American Journal of Cardiology 2011; 4(107):579–582.

Badheka A. O., Rathod Ankit., Kizilbash M. A., Garg N., Mohamad T., Afonso L., Jacob S. Influence of Obesity on Outcomes in Atrial Fibrillation: Yet Another Obesity Paradox. The American Journal of Medicine 2010; 7(123):646-651.

Abed H. S.,Wittert G. A., Leong D. P., Shirazi M. G., Bahrami B., Middeldorp M. E., Lorimer M. F., Lau D. H., Antic N. A., Brooks A. G., Abhayaratna W. P., Kalman J. M., Sanders P. Effect of weight reduction and cardiometabolic risk factor management on symptom burden and severity in patients with atrial fibrillation: a randomized clinical trial. JAMA 2013;310:2050–2060.

Pathak R. K., Middeldorp M. E., Meredith M., Mehta A. B., Mahajan R., Wong C. X., Twomey D., Elliott A. D., Kalman J. M., Abhayaratna W. P., Lau D. H., Sanders P. Long- term effect of goal directed weight management in an atrial fibrillation cohort: a long-term follow-up study (legacy study). J Am Coll Cardiol 2015;65:2159–2169.

How to Cite

1.
Pysarevska KO. The prevalence of obesity in patients with non-valvular persistent atrial fibrillation during long observations. Zaporozhye Medical Journal [Internet]. 2016May23 [cited 2024Dec.25];18(2). Available from: http://zmj.zsmu.edu.ua/article/view/69171

Issue

Section

Original research