Features of daily blood pressure fluctuations in patients with obstructive sleep apnea syndrome and obesity

Authors

  • O. I. Tokarenko SI «Zaporizhzhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine»,
  • Ya. O. Andreeva SI «Zaporizhzhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine»,

DOI:

https://doi.org/10.14739/2310-1210.2016.6.85492

Keywords:

obstructive sleep apnea syndrome, obesity, blood pressure, daily profile

Abstract

Objective: to study the features of daily blood pressure fluctuations according to the ambulatory blood pressure monitoring (ABPM) in patients with obstructive sleep apnea syndrome (OSAS) and obesity without arterial hypertension (AH).

Methods. The study included 86 patients with OSAS and obesity (group 1), 74 obese patients without OSAS (group 2) and 52 patients with OSAS and normal body weight (group 3). The control group consisted of 20 healthy individuals. All participants of the study were carried out physical examination, cardio-respiratory monitoring and ABPM.

Results. Systolic and diastolic blood pressure levels in patients from the 1st group were higher than in the control group for the whole day and night. The highest levels of SBP and DBP during the day and night were registered in the 1st group. It has been found that IV for SBP per day exceeded control values by 22%, 22% and 17% in the 1st, 2nd and the 3rd groups, respectively. Average daily IV for DAT was elevated in 15, 12 and 6 patients from the 1st, 2nd and the 3rd groups, respectively. Among the pathological daily profiles «non - dipper» was the predominant. Patients of all three groups more frequently showed significantly increased of SBP and DBP daytime and night time variability than the patients of control group.

Conclusions

1. Patients with OSAS and obesity have insufficient blood pressure reduction at night for both SBP and DBP, higher variability of blood pressure during the day, higher level of pressure load index.

2. Inmultiple regression analysis it has been defined the relationship between AHI and SBP at night (β = 0,403, p <0.05), as well as AHI, night DBP (β = 0,308, p <0.05) and BMI (β = 0,314, p <0.05).

References

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How to Cite

1.
Tokarenko OI, Andreeva YO. Features of daily blood pressure fluctuations in patients with obstructive sleep apnea syndrome and obesity. Zaporozhye medical journal [Internet]. 2016Dec.8 [cited 2024Apr.19];18(6). Available from: http://zmj.zsmu.edu.ua/article/view/85492

Issue

No. 6 (2016): Zaporozhye medical journal

Section

Original research

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