Predictors of a prolonged course of community-acquired pneumonia
DOI:
https://doi.org/10.14739/2310-1210.2017.2.95673Keywords:
pneumonia, prolonged course, рredictorsAbstract
Almost 30% of patients with community-acquired pneumonia have prolonged duration and association with increase of complications, length of hospital stay, treatment costs and mortality.
Aim: To find the predictors of community-acquired pneumonia prolonged course.
Material and Methods. 100 patients with community-acquired pneumonia group 3 were included in the randomized, controlled, prospective open study. The average age of patients was 43,63 ± 14,58 years, 59% were men. Patients were divided into two groups depending on the character and severity of pneumonia: prolonged course (more than 21 days) was in 15 patients, other (n = 85) recovered within 3 weeks. All patients have been examined on the first day of hospitalization by general clinical and X-ray examination, laboratory tests, immunogram, ADP-induced platelet aggregation, the study of respiratory function, transthoracic echocardiography; glomerular filtration rate was calculated by Cockcroft-Gault formula.
Results and Discussion. Patients with community-acquired pneumonia group 3with a prolonged duration represented 15% of the total number involved in our study patients, and had 65% more length of hospital stay. According to logistic regression model the predictors of prolonged duration of community-acquired pneumonia are a fasting blood sugar, glomerular filtration rate by Cockcroft-Gault, time of ADP-induced platelet aggregation, body mass index, heart rate, blood flow in the pulmonary artery, the reserve volume of inhalation. There are independent risk factors for community-acquired pneumonia with prolonged duration: blood glucose level less than 4.8 mmol / L, glomerular filtration rate less than 82 mL / min, body mass index less than23.12 kg / m2, the time of ADP -induced platelet aggregation is 370 s.
Conclusions. Independent risk factors for community-acquired pneumonia with prolonged duration are: blood glucose level (Odds Ratio = 27,87; p = 0,037), glomerular filtration rate (OR = 16,95; p = 0,011), body mass index (OR = 19,72; p = 0,030), time of ADP-induced platelet aggregation (OR = 37,02; p = 0,011).
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