Open surgical repair of abdominal aortic aneurysms and dissecting aneurysms in patients with coronary artery disease: a single-center experience

Authors

DOI:

https://doi.org/10.14739/2310-1210.2025.5.334168

Keywords:

abdominal aortic aneurysm, dissecting aneurysm, coronary artery disease, coronary artery bypass grafting, coronary stenting, surgical repair, myocardial revascularization, comorbidities, surgical treatment, in-hospital mortality

Abstract

Aim. To summarize the experience of pre- and postoperative management of patients with abdominal aortic aneurysms or dissections associated with coronary artery disease (CAD), and to evaluate the effectiveness of open surgical repair combined with myocardial revascularization based on a single specialized center’s clinical experience.

Materials and methods. The study included 75 patients (100.0 %) with infrarenal abdominal aortic aneurysms. Patients were initially divided into subgroup A (non-dissecting aneurysm) and subgroup B (dissecting aneurysm). All patients were then further stratified into three groups: Group 1 (comparison group) included patients without a diagnosed CAD; Group 2 consisted of patients with CAD who had previously undergone stenting or coronary artery bypass grafting (CABG) / off-pump coronary artery bypass (OPCAB); and Group 3 comprised patients with CAD who, during the same hospitalization, underwent surgical correction of both CAD and abdominal aortic aneurysm.

Results. Most patients who underwent myocardial revascularization (Groups 2 and 3) had multivessel coronary artery disease (MVCAD), confirmed by coronary ventriculography (CVG). Triple-vessel disease was observed in 78.9 % of patients, double-vessel disease in 15.8 %, and significant left main coronary artery stenosis (≥70 %) in 5.3 %. Patients who underwent CABG / OPCAB had an average ICU stay of 59.89 ± 20.20 hours, with a mean mechanical ventilation (MV) duration of 5.00 ± 2.40 hours. In the same group, after abdominal aortic aneurysm correction, the average ICU stay was 78.92 ± 53.93 hours, and the mean MV duration was 7.58 ± 6.71 hours. The overall complication rate was the highest in Group 1 (37.84 %), where the most extensive reconstructive procedures were performed. The highest postoperative in-hospital mortality was also observed in Group 1 in 4 (10.81 %) cases.

Conclusions. Myocardial revascularization should take priority over aortic reconstruction. This approach minimizes the risk of ischemic complications and allows for a safe transition to the next stage of treatment. A comparative analysis of the three clinical groups showed the worst outcomes in patients without prior revascularization, statistically confirming the effectiveness of a comprehensive treatment strategy (p < 0.05).

Author Biographies

I. I. Zhekov, National M. Amosov Institute of Cardiovascular Surgery affiliated to National Academy of Medical Sciences of Ukraine, Kyiv

MD, PhD, Cardiovascular Surgeon, Senior Researcher at the Department of Surgical Treatment of Aortic Pathology

A. V. Rudenko, National M. Amosov Institute of Cardiovascular Surgery affiliated to National Academy of Medical Sciences of Ukraine, Kyiv

MD, PhD, DSc, Professor, Deputy Director for Scientific Work; Corresponding Member of the National Academy of Sciences of Ukraine, Academician of the National Academy of Medical Sciences of Ukraine

A. S. Bulakh, National M. Amosov Institute of Cardiovascular Surgery affiliated to National Academy of Medical Sciences of Ukraine, Kyiv

MD, Cardiovascular Surgeon, Staff Member at the Department of Surgical Treatment of Aortic Pathology

I. P. Makohonchuk, National M. Amosov Institute of Cardiovascular Surgery affiliated to National Academy of Medical Sciences of Ukraine, Kyiv

MD, Cardiovascular Surgeon Junior Researcher at the Department of Surgical Treatment of Aortic Pathology

K. V. Rudenko, National M. Amosov Institute of Cardiovascular Surgery affiliated to National Academy of Medical Sciences of Ukraine, Kyiv

MD, PhD, DSc, Deputy Director for Scientific Coordination; Corresponding Member of the National Academy of Medical Sciences of Ukraine

References

Moll FL, Powell JT, Fraedrich G, Verzini F, Haulon S, Waltham M, et al. Management of abdominal aortic aneurysms clinical practice guidelines of the European society for vascular surgery. Eur J Vasc Endovasc Surg. 2011;41 Suppl 1:S1-S58. doi: https://doi.org/10.1016/j.ejvs.2010.09.011

Dereziński TL, Fórmankiewicz B, Migdalski A, Brazis P, Jakubowski G, Woda Ł, et al. The prevalence of abdominal aortic aneurysms in the rural/urban population in central Poland – Gniewkowo Aortic Study. Kardiol Pol. 2017;75(7):705-10. doi: https://doi.org/10.5603/KP.a2017.0071

Golledge J, Muller J, Daugherty A, Norman P. Abdominal aortic aneurysm: pathogenesis and implications for management. Arterioscler Thromb Vasc Biol. 2006;26(12):2605-13. doi: https://doi.org/10.1161/01.ATV.0000245819.32762.cb

Ye Z, Bailey KR, Austin E, Kullo IJ. Family history of atherosclerotic vascular disease is associated with the presence of abdominal aortic aneurysm. Vasc Med. 2016;21(1):41-6. doi: https://doi.org/10.1177/1358863X15611758

Van Kuijk JP, Flu WJ, Dunckelgrun M, Bax JJ, Poldermans D. Coronary artery disease in patients with abdominal aortic aneurysm: a review article. J Cardiovasc Surg (Torino). 2009;50(1):93-107.

Elkalioubie A, Haulon S, Duhamel A, Rosa M, Rauch A, Staels B, et al. Meta-Analysis of Abdominal Aortic Aneurysm in Patients With Coronary Artery Disease. Am J Cardiol. 2015;116(9):1451-6. doi: https://doi.org/10.1016/j.amjcard.2015.07.074

Hertzer NR, Beven EG, Young JR, O’Hara PJ, Ruschhaupt WF 3rd, Graor RA, et al. Coronary artery disease in peripheral vascular patients. A classification of 1000 coronary angiograms and results of surgical management. Ann Surg. 1984;199(2):223-33. doi: https://doi.org/10.1097/00000658-198402000-00016

Hołda MK, Iwaszczuk P, Wszołek K, Chmiel J, Brzychczy A, Trystuła M, et al. Coexistence and management of abdominal aortic aneurysm and coronary artery disease. Cardiol J. 2020;27(4):384-93. doi: https://doi.org/10.5603/CJ.a2018.0101

Islamoğlu F, Atay Y, Can L, Kara E, Ozbaran M, Yüksel M, et al. Diagnosis and treatment of concomitant aortic and coronary disease: a retrospective study and brief review. Tex Heart Inst J. 1999;26(3):182-8.

Keisler B, Carter C. Abdominal Aortic Aneurysm. Am Fam Physician. 2015;91(8):538-43.

Jana S, Hu M, Shen M, Kassiri Z. Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm. Exp Mol Med. 2019;51(12):1-15. doi: https://doi.org/10.1038/s12276-019-0286-3

Juo YY, Mantha A, Ebrahimi R, Ziaeian B, Benharash P. Incidence of Myocardial Infarction After High-Risk Vascular Operations in Adults. JAMA Surg. 2017;152(11):e173360. doi: https://doi.org/10.1001/jamasurg.2017.3360

Khan FM, Naik A, Hameed I, Robinson NB, Spadaccio C, Rahouma M, et al. Open Repair of Descending Thoracic and Thoracoabdominal Aortic Aneurysms: A Meta-Analysis. Ann Thorac Surg. 2020;110(6):1941-9. doi: https://doi.org/10.1016/j.athoracsur.2020.04.069

Neumann FJ, Sousa-Uva M, Ahlsson A, Alfonso F, Banning AP, Benedetto U, et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J. 2019;40(2):87-165. doi: https://doi.org/10.1093/eurheartj/ehy394. Erratum in: Eur Heart J. 2019;40(37):3096. doi: https://doi.org/10.1093/eurheartj/ehz507

Chau K, Elefteriades JA. Ascending thoracic aortic aneurysms protect against myocardial infarctions. Int J Angiol. 2014;23(3):177-82. doi: https://doi.org/10.1055/s-0034-1382288

Quintana E, Bajona P, Schaff HV, Dearani JA, Daly R, Greason K, et al. Open Aortic Arch Reconstruction After Coronary Artery Bypass Surgery: Worth the Effort? Semin Thorac Cardiovasc Surg. 2016;28(1):26-35. doi: https://doi.org/10.1053/j.semtcvs.2015.12.006

Williams AM, Watson J, Mansour MA, Sugiyama GT. Combined Coronary Artery Bypass Grafting and Abdominal Aortic Aneurysm Repair: Presentation of 3 Cases and a Review of the Literature. Ann Vasc Surg. 2016;30:321-30. doi: https://doi.org/10.1016/j.avsg.2015.06.072

Morimoto K, Taniguchi I, Miyasaka S, Aoki T, Kato I, Yamaga T. Usefulness of One-Stage Coronary Artery Bypass Grafting on the Beating Heart and Abdominal Aortic Aneurysm Repair. Ann Thorac Cardiovasc Surg. 2004;10(1):29-33.

Additional Files

Published

2025-11-07

How to Cite

1.
Zhekov II, Rudenko AV, Bulakh AS, Makohonchuk IP, Rudenko KV. Open surgical repair of abdominal aortic aneurysms and dissecting aneurysms in patients with coronary artery disease: a single-center experience. Zaporozhye Medical Journal [Internet]. 2025Nov.7 [cited 2025Nov.8];27(5):410-6. Available from: https://zmj.zsmu.edu.ua/article/view/334168