Experience in the comprehensive management of gunshot shrapnel wounds of soft tissues at various locations

Authors

DOI:

https://doi.org/10.14739/2310-1210.2025.5.338078

Keywords:

gunshot shrapnel wounds, PRP therapy, delayed primary sutures, early secondary sutures, autodermoplasty, flap reconstruction

Abstract

Aim. To develop a comprehensive strategy for the treatment of isolated gunshot shrapnel wounds of soft tissues at various locations.

Materials and methods. This study analyzed outcomes in 5,000 patients of working age (18–49 years) treated for isolated gunshot and shrapnel soft-tissue wounds at hospitals in Zaporizhzhia and the Zaporizhzhia Military Hospital between March 2022 and June 2025. The injuries were predominantly localized in the lower extremities (67.06 %), less frequently in the upper extremities (25.14 %) and trunk (7.78 %). Different treatment approaches were applied: platelet-rich plasma (PRP) in combination with delayed primary sutures (DPS) or early secondary closure (ESC), modified autodermoplasty, and local or free flap reconstructions.

Results. PRP combined with suturing was applied in 3851 cases (77.02 %): DPC in 2394 (47.88 %) and ESC in 1457 (29.14 %). The complication rates were 7.81 % with DPC and 8.86 % with ESC, while the average hospital stay was 16.0 ± 3.1 and 22.0 ± 2.2 days, respectively. In 1149 cases (22.98 %), plastic techniques were required: modified autodermoplasty in 953 (19.06 %) and flap reconstructions in 196 (3.92 %). These methods enabled the closure of extensive defects but were associated with higher complication rates (25.6–67.9 %) and longer hospital stays (23.0–36.8 days).

Conclusions. The use of PRP in combination with delayed primary or early secondary closure is the most effective and safe treatment strategy for small, isolated gunshot shrapnel wounds of soft tissues, ensuring low complication rates and faster functional recovery. Autodermoplasty and flap techniques remain the methods of choice for large and deep defects but require advanced surgical expertise and are associated with longer rehabilitation.

Author Biographies

S. M. Zavhorodnii, Zaporizhzhia State Medical and Pharmaceutical University

MD, PhD, DSc, Professor, Head of the Department of General Surgery and Postgraduate Surgical Education, Educational and Scientific Institute of Postgraduate Education

M. A. Kubrak, Zaporizhzhia State Medical and Pharmaceutical University

MD, PhD, Associate Professor of the Department of General Surgery and Postgraduate Surgical Education, Educational and Scientific Institute of Postgraduate Education

M. B. Danyliuk, Zaporizhzhia State Medical and Pharmaceutical University

MD, PhD, Associate Professor of the Department of General Surgery and Postgraduate Surgical Education, Educational and Scientific Institute of Postgraduate Education

Iu. O. Mikheiev, Zaporizhzhia State Medical and Pharmaceutical University

MD, PhD, DSc, Associate Professor, Professor of the Department of Disaster Medicine and Military Medicine; Major of the Medical Service, Leading Surgeon, Zaporizhzhia Military Hospital, Military Unit A3309

O. I. Kotenko, Zaporizhzhia State Medical and Pharmaceutical University

MD, PhD, Assistant at the Department of General Surgery and Postgraduate Surgical Education, Educational and Scientific Institute of Postgraduate Education

P. O. Bulba, Zaporizhzhia State Medical and Pharmaceutical University

MD, PhD student, Department of General Surgery and Postgraduate Surgical Education, Educational and Scientific Institute of Postgraduate Education

I. M. Bielkin, Zaporizhzhia Military Hospital

MD, Senior Lieutenant of the Medical Service, Head of the Operating Unit, Zaporizhzhia Military Hospital, Military Unit A3309

D. V. Tkachuk, Zaporizhzhia State Medical and Pharmaceutical University

MD, PhD student of the Department of Disaster Medicine and Military Medicine, Senior Resident of the Surgical Department, Zaporizhzhia Military Hospital

References

Balazh MS, Shestopal NO. [Modern approaches to physical therapy measures in individuals with gunshot injuries of the upper limb]. Sportyvna medytsyna, fizychna terapiia ta erhoterapiia. 2028;(2):68-74. Ukrainian. doi: https://doi.org/10.32652/spmed.2018.2.68-74

Gybalo RV, Batiuk AI. [Features of the up-to-date approach to diagnosis and treatment of patients with postoperative ventral hernias after multi-stage surgical treatment of open gunshot wounds]. Suchasni aspekty viiskovoi medytsyny. 2020;27(2):321-31. Ukrainian. doi: https://doi.org/10.32751/2310-4910-2020-27-54

Zavhorodnii SM, Kotenko OI, Danyliuk MB, Kubrak MA. [Surgical treatment of isolated gunshot shrapnel wounds of soft tissues using delayed primary sutures combined with platelet-rich plasma injections in mine-explosive injuries]. Zaporizhzhia Medical Journal. 2023;25(4):339-45. Ukrainian. doi: https://doi.org/10.14739/2310-1210.2023.4.269875

Kukuruz YS, Slychko IY, Yalovenko VA. [Peculiarities of teaching for reserve officers ofsurgical tactics at fire and open injury of extremities]. Medychna osvita. 2013;(4):94-6. Ukrainian. doi: https://doi.org/10.11603/me.v0i4.1095

Neroba V. [The role of mining weapons in the modern wars and border conxicts]. Collection of scientific works of the National Academy of the State Border Guard Service of Ukraine. Series: Military and Technical Sciences. 2019;(3):155-71. Ukrainian. doi: https://doi.org/10.32453/3.v81i3.444

Chernyak VA, Rogovsky VM, Nahaliuk YV, Sivash YY, Shchepetov MV, Karpenko KK. [Results of the treatment of major vacuum wounds in the united kingdom’s operation in the eastern ukraine for the period from 2014 to and quarter of 2019]. Scientific Bulletin of Uzhhorod University. Series: Medicine. 2020;61(1):130-9. Ukrainian. doi: https://doi.org/10.24144/2415-8127.2020.61.130-139

Ahmad S, Agrawal P, Anwer A, Khurana S, Adil M, Ibran M. Gunshot Injury to Distal Tibial Physis and Talus: A Case Report. J Orthop Case Rep. 2024;14(4):134-9. doi: https://doi.org/10.13107/jocr.2024.v14.i04.4388

Zavhorodnii SM, Kotenko OI. [Effectiveness of the use of early secondary sutures and injections of platelet-rich autoplasma in isolated gunshot shrapnel wounds of soft tissues]. Reports of Vinnytsia National Medical University. 2024;28(2):287-93. Ukrainian. doi: https://doi.org/10.31393/reports-vnmedical-2024-28(2)-18

Feliciano DV. Gunshot wound to big red. Trauma Surg Acute Care Open. 2020;5(1):e000506. doi: https://doi.org/10.1136/tsaco-2020-000506

Martin P, Gurevich DB. Macrophage regulation of angiogenesis in health and disease. Semin Cell Dev Biol. 2021;119:101-10. doi: https://doi.org/10.1016/j.semcdb.2021.06.010

Liashevych AM, Lupaina IS, Hryshchuk SM. Dynamichna anatomiia [Dynamic Anatomy]. Zhytomyr: Zhytomyr State University Press; 2022. Ukrainian.

Pykaliuk VS, Lavryniuk VY, Shevchuk TY, Aponchuk LS. Anatomiia oporno-rukhovoho aparatu [Anatomy of the Musculoskeletal System]. Lutsk: FOP Ivaniuk V. P.; 2022. Ukrainian.

Mishra JK, Sahu SA, Bodhey NK, Sindhuja A, V A. Perforator-based propeller flap with additional venous pedicle for lower limb reconstruction. Indian J Plast Surg [Internet]. 2023;56(4):373-7. doi: https://doi.org/10.1055/s-0043-1769113

Yu JL, Tolley PD, Kneib C, Miller EA, Crowe CS. Current concepts in microsurgical soft tissue reconstruction of lower extremity trauma in a single-vessel extremity. Plast Aesthet Res. 2022;9(5):37. doi: https://doi.org/10.20517/2347-9264.2021.124

List EB, Hahn BA, Qiu SS, de Jong T, Rakhorst HA, Verheul EM, et al. Free Fasciocutaneous versus Muscle Flaps in Lower Extremity Reconstruction: Implications for Functionality and Quality of Life. J Reconstr Microsurg. 2024 Dec 20. doi: https://doi.org/10.1055/a-2483-5388

Downloads

Additional Files

Published

2025-11-07

How to Cite

1.
Zavhorodnii SM, Kubrak MA, Danyliuk MB, Mikheiev IO, Kotenko OI, Bulba PO, Bielkin IM, Tkachuk DV. Experience in the comprehensive management of gunshot shrapnel wounds of soft tissues at various locations. Zaporozhye Medical Journal [Internet]. 2025Nov.7 [cited 2025Nov.8];27(5):398-404. Available from: https://zmj.zsmu.edu.ua/article/view/338078