Disorders of bone-mineral metabolism and their correction with women who have body weight deficiency at pregravid stage and during pregnancy
DOI:
https://doi.org/10.14739/2310-1210.2017.5.110167Keywords:
body weight, preventive medicine, preconception care, pregnancy, bone-density, densitometryAbstract
The processes in bone-mineral metabolism provide normal course of pregnancy, labour and fetus development, women with body weight deficiency are at risk reduction of bone tissue mineral density, progressing of osteopenia and osteoporosis. This shows the necessity of medical and preventive measures that have the aim to correct calcium- phosphorus and bone metabolism with women who have body weight deficiency.
Aim. To elaborate and to evaluate medical and preventive measures that have the aim to correct disorders in bone-mineral metabolism with women who have body weight deficiency at pregravid stage and during pregnancy.
Materials and methods. The efficiency of adding combined medicine of calcium carbonate and cholecalciferol and dietary nourishment to traditional treatment that affected the state of bone-mineral metabolism with women who have body weight deficiency at pregravid stage and during pregnancy was studied.
Results. With women who have body weight deficiency at pregravid stage and during pregnancy it is noted statistically considerable reduction in blood of total calcium and bone tissue markers that grows with the course of gestation. The changes in mineral density of bone tissue can be seen from the existence of osteopenic syndrome at pregravid stage that occurs with every third woman who has body weight deficiency and with every second before labour. The use of elaborated medical and preventive measures including combined medicine of calcium carbonate and cholecalciferol allows to normalize the indexes of bone-mineral metabolism with women who have body weight deficiency.
Conclusions. Women with body weight deficiency already at pregravid stage have disorders in bone metabolism and coming of pregnancy lead to aggravation of bone metabolism disorders. The additional use of combined medicine of calcium carbonate and cholecalciferol and dietary nourishment made the indexes of calcium-phosphorus and bone metabolism better and osteopenic syndrome less frequent.
References
Dumanskaya, Yu., & Shcherbavskaya, E. (2009) Issledovanie kostnoj tkani metodom dvukhe´nergeticheskoj rentgenovskoj absorbciometriej u devochek-podrostkov s narusheniem menstrual'nogo cikla [The Study of Bone Tissue by Method of Two-Energy X-Ray Absorptiometry in Teenager-Girls with Inpairment of Menstrual Functions]. Vestnik novykh medicinskikh tehnologij, 16(3), 56 58. [in Russian].
Hollis, B. W., Johnson, D., Hulsey, T. C. Ebeling, M., & Wagner, C. L. (2011) Vitamin D supplementation during pregnancy: doubl-blind, randomized clinical trial of safety and effectiveness. J Bone Miner Res, 26(10), 2341 57. doi: 10.1002/jbmr.463.
Achkar, M., Dodds, L., Giguère, Y., Forest, J. C., Armson, B. A., Woolcott, C., et al. (2015) Vitamin D status in early pregnancy and risk of preeclampsia. Am J Obstet Gynecol, 212(4), 511. doi: 10.1016/j.ajog.2014.11.009.
Zhou, J., Su, L., Liu, M., Liu, Y., Cao, X., Wang, Z. & Xiao, H. (2014) Associations between 25-hydroxyvitamin D levels and pregnancy outcomes: a prospective observational study in southern China. Eur J Clin Nutr, 68(8), 925 30. doi: 10.1038/ejcn.2014.99.
Price, C. T., Langford, J. R. & Liporace, F. A. (2012) Essential nutrients for bone health and a review of their availability in the average North American diet. Open Orthopaedics J, 6, 143 9. doi: 10.2174/1874325001206010143.
Kodencova, V. M., Vrzhesinskaya, O. A., Svetikova, A. A. & Kaganov, B. S. (2009) Alimentarnye faktory riska razvitiya osteoporoza [Alimentary risk factors of osteoporosis]. Voprosy pitaniya, 178(1), 22 33. [in Russian].
Shherbavskaya, E´. A., & Gel'cer, B. I. (2003) Patofiziologicheskie aspekty osteopenii i osteoporoza pri beremennosti [Pathophysiological aspects of osteopenia and osteoporosis in pregnancy]. Rossijskie medicinskie vesti, 8(2), 28 33. [in Russian].
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