Сorrelation «structure – anticancer activity» 4-thiazolidone with benzotiazolnym fragments in the molecule

Authors

  • L. M. Mosula

DOI:

https://doi.org/10.14739/2310-1210.2013.1.15506

Keywords:

antitumor activity, 4-thiazolidones, benzothiazole moeity, COMPARE analysis

Abstract

In this article the antitumor activity of 4-thiazolidone derivatives with benzothiazole moiety in the molecules were analyzed. The «structure – antitumor activity» relationship was described. The potential pharmacophore for this derivatives was identified. Two compounds show highly antitumor activity from the whole with all cell lines which identified. COMPARE analysis to known antitumor agents for determination the possible mechanism of the antitumor activity of the main compound which been developed.

Downloads

Published

2013-07-15

How to Cite

1.
Mosula LM. Сorrelation «structure – anticancer activity» 4-thiazolidone with benzotiazolnym fragments in the molecule. Zaporozhye Medical Journal [Internet]. 2013Jul.15 [cited 2024Nov.2];15(1). Available from: http://zmj.zsmu.edu.ua/article/view/15506

Issue

No. 1 (2013): Zaporozhye medical journal

Section

Problems of pharmacy

License

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.  Лицензия Creative Commons
    2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
    3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)