Сorrelation «structure – anticancer activity» 4-thiazolidone with benzotiazolnym fragments in the molecule

Authors

  • L. M. Mosula

DOI:

https://doi.org/10.14739/2310-1210.2013.1.15506

Keywords:

antitumor activity, 4-thiazolidones, benzothiazole moeity, COMPARE analysis

Abstract

In this article the antitumor activity of 4-thiazolidone derivatives with benzothiazole moiety in the molecules were analyzed. The «structure – antitumor activity» relationship was described. The potential pharmacophore for this derivatives was identified. Two compounds show highly antitumor activity from the whole with all cell lines which identified. COMPARE analysis to known antitumor agents for determination the possible mechanism of the antitumor activity of the main compound which been developed.

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Published

2013-07-15

How to Cite

1.
Mosula LM. Сorrelation «structure – anticancer activity» 4-thiazolidone with benzotiazolnym fragments in the molecule. Zaporozhye medical journal [Internet]. 2013Jul.15 [cited 2024Apr.20];15(1). Available from: http://zmj.zsmu.edu.ua/article/view/15506

Issue

No. 1 (2013): Zaporozhye medical journal

Section

Problems of pharmacy

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