Recurrent respiratory diseases in practice of family physician and pediatrician: main issues (a literature review)
DOI:
https://doi.org/10.14739/2310-1210.2019.6.186715Keywords:
children, respiratory diseases, diagnosis, treatmentAbstract
The aim of the study – to analyze the professional literature and evaluate modern scientific trends concerning definition, peculiarities of etiopathogenesis, differential diagnosis and prevention of recurrent respiratory diseases (RRD) in the practice of family doctors and pediatricians.
Conclusions. Respiratory diseases in children can play an ambiguous role, because on the one hand, they are an inducement for the host defenses, while they can cause secondary immune dysfunction in a significant increase in their incidence and severity, on the other. However, there are no specific criteria for RRD diagnosis. Contributing factors include harmful ecological conditions, unfavorable family history, absence of breastfeeding, presence of comorbid pathology and many other factors. Some children with RRD have immune dysfunctions, including changes in nonspecific protection and cellular immunity. Even if there are no changes in the main immunological indices, RRD can occur.
Children with RRD require special attention, because severe, sometimes incurable diseases can be under the mask of frequent RRD. For such children family doctor and pediatrician should conduct a differential diagnosis with atopy, primary immune deficiency, gastroesophageal reflux, bronchial foreign body, cystic fibrosis, psychogenic cough and other diseases. Children with chronic infection should also be separated.
In order to adequately assess the situation and develop a well-grounded treatment tactics for such patients, it is necessary to work out domestic criteria for assigning children to the RRD group.
A physician should provide an individual approach to such a patient with optimal diagnostic methods and the development of management tactics both in acute episodes of respiratory diseases and during non-acute periods with the maximum involvement of drug-free modalities and for prevention of the pathological process progression.
References
Albickij, V. Ju., Baranov, A. A. (1986). Chasto bolejushhie deti. Kliniko-socialnye aspekty. Puti ozdorovlenija [Children who are frequently ill. Clinical and social aspects. Recovery ways]. Saratov. [in Russian].
Makarova, Z. (2016). Sostojanie zdorovja i osnovnye napravlenija ozdorovlenija chasto bolejushhih detej [Health status and the main directions of improvement of often ill children]. Preschool education, 9, 63-69. [in Russian].
Samsygina, G. A., Vyzhlova, E. N. (2016). Eshhe raz o problemah ponjatija «chasto bolejushhie deti» [Once again about the problems of «frequently ill children» notion]. Pediatria, 95(4), 209-215. [in Russian].
Word Health Organization. Classifications. Retrieved from https://www.who.int/classifications/icd/en/.
Bush, A. (2009). Recurrent respiratory infections. Pediatric Clinics Of North America, 56(1), 67-100. doi: 10.1016/j.pcl.2008.10.004
Jesenak, M., Ciljakova, M., Rennerova, Z., Babusikova, E., & Banovci, P. (2011). Recurrent Respiratory Infections in Children – Definition, Diagnostic Approach, Treatment and Prevention. Bronchitis. Retrieved from https://www.intechopen.com/books/bronchitis/recurrent-respiratory-infections-in-children-definition-diagnostic-approach-treatment-and-prevention. doi: 10.5772/19422
Raniszewska, A., Górska, E., Kotuła, I., Stelmaszczyk-Emmel, A., Popko, K., & Ciepiela, O. (Raniszewska, A., Górska, E., Kotuła, I., Stelmaszczyk-Emmel, A., Popko, K., & Ciepiela, O.). Recurrent respiratory tract infections in children – analysis of immunological examinations. Central European Journal Of Immunology, 40(2), 167-173. doi: 10.5114/ceji.2015.52830
Hai-Feng, L., Yan, Z., Pei-Gang, J., & Hong-Xing, J. (2014). Risk factors for recurrent respiratory infections in preschool children in china. Iranian Journal of Pediatrics, Iranian Journal of Pediatrics.
Ruuskanen, O., Nurkka, A., Helminen, M., Viljanen, M., Käyhty, H., & Kainulainen, L. (2013). Specific antibody deficiency in children with recurrent respiratory infections: a controlled study with follow-up. Clinical & Experimental Immunology, 172(2), 238-244. doi: 10.1111/cei.12053
Schaad, U., Esposito, S., & Razi, C. (2015). Diagnosis and Management of Recurrent Respiratory Tract Infections in Children: A Practical Guide. Archives Of Pediatric Infectious Diseases, 4(1), e31039. doi: 10.5812/pedinfect.31039
Macchi, A., Esposito, C., Debernardi, F., Simoncini, D., Peirolo, A., & Castelnuovo, P. (2018). The role of immunomodulation therapy in preventing recurrent respiratory infections in children. Retrieved from https://www.researchgate.net/publication/323079575_The_role_of_immunomodulation_therapy_in_preventing_recurrent_respiratory_infections_in_children.
Sütçü, M., Acar, M., Aktürk, H., Hançerli-Törün, S., Salman, N., & Somer, A. (2016). Recognizing immunodeficiency in children with recurrent infections: what are the predictive factors? The Turkish Journal Of Pediatrics, 58(6), 609-615. doi: 10.24953/turkjped.2016.06.006
El-Azami-El-Idrissi, M., Lakhdar-Idrissi, M., Chaouki, S., Atmani, S., Bouharrou, A., & Hida, M. (2016). Pediatric recurrent respiratory tract infections: when and how to explore the immune system? (About 53 cases). Pan African Medical Journal, 24, 53. doi: 10.11604/pamj.2016.24.53.3481
Rudenko, A., Yukhymenko, O., Zelena, N., Tarasova, I., Sliusarev, O., & Samarin, D. et al. (2015). Znachennia antybakterialnoi terapii u likuvanni ditei z retsydyvnymy infektsiiamy verkhnikh dykhalnykh shliakhiv [Importance antibiotic therapy in treating children with recurrent upper respiratory tract infections]. Modern pediatrics, 71(7), 80-85. doi: 10.15574/sp.2015.71.80 [in Ukrainian].
Chernyshova, L. I. (2018). Rekurentni respiratorni zakhvoriuvannia u ditei: alhorytm dii likaria (lektsiia) [Recurrent respiratory diseases in children: the physician's action algorithm (lecture)]. Modern pediatrics, 3(91), 92-97. doi: 10.15574/SP.2018.91.92 [in Ukrainian].
Lafond, K., Nair, H., Rasooly, M., Valente, F., Booy, R., & Rahman, M. et al. (2016). Global Role and Burden of Influenza in Pediatric Respiratory Hospitalizations, 1982-2012: A Systematic Analysis. PLOS Medicine, 13(3), e1001977. doi: 10.1371/journal.pmed.1001977
Levchyn, A. M. (2013). Klinichna kharakterystyka ditei 1-5 rokiv iz rekurentnymy respiratornymy infektsiiamy [Clinical characteristic of children of 1-5 years with recurrent respiratory infections]. Ukrainian medical almanac,16(1), 26-28
Chopiak, V. V., Potomkina, H. O., Kril, I. Y., Bilianska, L. M., Mazurak, M. V., & Lishchuk-Iakymovych, Kh. O. (2015). Doslidzhennia rehuliatornykh imunnykh mekhanizmiv ta mozhlyvostei yikh korektsii u ditei, shcho chasto khvoriiut [Examination of regulatory immune mechanisms in friqantlly ill children and their correctability]. Modern pediatrics, 3(67). С. 80-87. doi: 10.15574/SP.2015.67.85 [in Ukrainian].
Carey, I., Critchley, J., DeWilde, S., Harris, T., Hosking, F., & Cook, D. (2018). Risk of Infection in Type 1 and Type 2 Diabetes Compared With the General Population: A Matched Cohort Study. Diabetes Care, 41(3), 513-521. doi: 10.2337/dc17-2131
Pateva, I. B., Kerling, E. H., Reddy, M., Chen, D., Carlson, S. E., & Tancabelic, J. (2015). Effect of maternal cigarette smoking on newborn iron stores. Clinical Research And Trials, 1(1), 4-7.
Kozakevych, O. B. (2016). Fizychnyi rozvytok vkrai nedonoshenykh ditei uprodovzh pershykh trokh rokiv zhyttia ta faktory ryzyku, shcho vplyvaiut na yoho znachnu zatrymku [Physical development extremely premature infants during the first three years of life and risk factors affecting its considerable delay]. Modern pediatrics, 4(76), 36-39. doi: 10.15574/SP.2016.76.36 [in Ukrainian].
Mukvich, O. M., & Kaminska, T. M. (2017). Preventyvna ta likuvalna efektyvnist bioflavonoidiv u ditei z rekurentnymy respiratornymy infektsiiamy [Preventive and therapeutic effectiveness of bioflavonoids in children with recurrent respiratory infections]. Child’s Health, 12(2), 124-129. doi: 10.22141/2224-0551.12.2.2017.99767 [in Ukrainian].
Bergman, P., Norlin, A., Hansen, S., & Björkhem-Bergman, L. (2015). Vitamin D supplementation to patients with frequent respiratory tract infections: a post hoc analysis of a randomized and placebo-controlled trial. BMC Research Notes, 8, 391. doi: 10.1186/s13104-015-1378-3
Lemko, O. I., Lukashchuk, S. V., Vantiukh, N. V., & Popadynets, M. I. (2017). Vplyv vidnovliuvalnoho likuvannia na imunnyi status ditei iz rekurentnymy respiratornymy zakhvoriuvanniamy [The influence of recovery treatment on the immune status of children with recurrent respiratory infections]. Child’s Health, 12(7), 773-779. doi: 10.22141/2224-0551.12.7.2017.116182 [in Ukrainian].
Yurochko, F. (2013). Retsydyvuiuchi respiratorni infektsii u ditei [Respіratory recurrent infections in children]. Modern pediatrics, 5(53), 91-96. [in Ukrainian].
(2012). Pro stvorennia ta vprovadzhennia medyko-tekhnolohichnykh dokumentiv zi standartyzatsii medychnoi dopomohy v systemi Ministerstva okhorony zdorovia Ukrainy nakaz MOZ Ukrainy vid 28.09.2012 roku №751. [About creation and implementation of medical-technological documents on standardization of medical care in the system of the Ministry of Health of Ukraine: order of the Ministry of Health of Ukraine from September 28, 2012 №751]. Retrieved from https://zakon.rada.gov.ua/laws/show/z2001-12. [in Ukrainian].
Bright, P., Rooney, N., Virgo, P., Lock, R., Johnston, S., & Unsworth, D. (2014). Laboratory clues to immunodeficiency; missed chances for early diagnosis? Journal Of Clinical Pathology, 68(1), 1-5. doi: 10.1136/jclinpath-2014-202618
Lear, S., & Condliffe, A. (2014). Respiratory infection and primary immune deficiency – what does the general physician need to know? The Journal Of The Royal College Of Physicians Of Edinburgh, 44(2), 149-155. doi: 10.4997/jrcpe.2014.214
Surendran, N., Nicolosi, T., Kaur, R., Morris, M., & Pichichero, M. (2016). Prospective study of the innate cellular immune response in low vaccine responder children. Innate Immunity, 23(1), 89-96. doi: 10.1177/1753425916678471
Arakawa, H., Hamasaki, Y., Kohno, Y., Ebisawa, M., Kondo, N., & Nishima, S. et al. (2017). Japanese guidelines for childhood asthma 2017. Allergology International, 66(2), 190-204. doi: 10.1016/j.alit.2016.11.003
Zheng, X., Xu, Y., Guan, W., & Lin, L. (2018). Regional, age and respiratory-secretion-specific prevalence of respiratory viruses associated with asthma exacerbation: a literature review. Archives Of Virology, 163(4), 845-853. doi: 10.1007/s00705-017-3700-y
Jartti, T., & Gern, J. (2017). Role of viral infections in the development and exacerbation of asthma in children. Journal Of Allergy And Clinical Immunology, 140(4), 895-906. doi: 10.1016/j.jaci.2017.08.003
Garcia-Garcia, M., Calvo Rey, C., & del Rosal Rabes, T. (2016). Asma y virus en el niño. Archivos De Bronconeumología, 52(5), 269-273. doi: 10.1016/j.arbres.2015.11.008
Maidannyk, V. H., Besh, L. V., Koloskova, O. K., & Smiian O. I. (2018). Bronkhialna astma u ditei: novi klinichni rekomendatsii [Bronchial asthma in children: new clinical guidelines]. International Journal of Pediatrics, Obstetrics and Gynecology, 12(1), 28-42. [in Ukrainian].
Sacco, O., Silvestri, M., Ghezzi, M., Capizzi, A., & Rossi, G. (2018). Airway inflammation and injury in children with prevalent weakly acidic gastroesophageal refluxes. Respiratory Medicine, 143, 42-47. doi: 10.1016/j.rmed.2018.08.011
Rybak, A., Pesce, M., Thapar, N., & Borrelli, O. (2017). Gastro-Esophageal Reflux in Children. International Journal Of Molecular Sciences, 18(8), 1671. doi: 10.3390/ijms18081671
Borisova, T. P., Badogina, L. P., T. V., & Fedko. (2018). Rekurrentnye respiratornye infekcii v pediatricheskoj praktike: jeffektivnost primenenija inozina pranobeksa [Recurrent respiratory infections in pediatric practice: the effectiveness of the use of inosine pranobex]. Child’s Health, 13(7), 674-680. doi: 10.22141/2224-0551.13.7.2018.148921 [in Ukrainian].
Lukashchuk, S. V., & Lemko, O. I. (2016). Pryntsypy vedennia ditei iz chastymy ta retsydyvnymy zakhvoriuvanniamy dykhalnykh shliakhiv (ohliad literatury) [The principles of treatment in children with frequent and recurrent respiratory diseases (literature review)]. Modern pediatrics, 7(79), 48-52. doi: 10.15574/SP.2016.79.48 [in Ukrainian].
Marushko, T. V., & Asonov, A. O. (2018). Osoblivostі mіscevoї terapії gostrih zapalnih zahvorjuvan rotoglotki u dіtej [Features of local therapy of acute inflammatory diseases of the oropharynx in children]. Modern pediatrics, 3(91), 98-101. doi: 10.15574/SP.2018.91.98 [in Ukrainian].
Jolliffe, D., Greenberg, L., Hooper, R., Griffiths, C., Camargo, C., & Kerley, C. et al. (2017). Vitamin D supplementation to prevent asthma exacerbations: a systematic review and meta-analysis of individual participant data. The Lancet Respiratory Medicine, 5(11), 881-890. doi: 10.1016/s2213-2600(17)30306-5
Passali, D., Gabelli, G., Passali, G., Mösges, R., & Bellussi, L. (2017). Radon-enriched hot spring water therapy for upper and lower respiratory tract inflammation. Otolaryngologia Polska, 71(4), 8-13. doi: 10.5604/01.3001.0010.2242
Pieshkova, O. V. (2015). Likuvalna fizychna kultura yak zasib profilaktyky dlia ditei, yaki chasto khvoriiut na hostri respiratorni zakhvoriuvannia [Therapeutic physical training as a means of prevention for children with frequent episodes of acute respiratory diseases]. Slobozhansky Scientific Journal Sports, 2(46), 154-160. doi: https://doi.org/10.15391/snsv.2015-2.030 [in Ukrainian].
Lemko, O. I., Lemko, I. S. (2018). Speleoterapiia, haloterapiia, haloaerozolterapiia: definitsii, mekhanizmy vplyvu, perspektyvy vykorystannia (chastyna II) [Speleotherapy, halotherapy, haloaerosoltherapy: definitions, mechanisms of influence, perspectives of usage (part ІІ)]. Asthma and Allergy, 3, 34-41. doi: 10.31655/2307-3373-2018-3-34-41 [in Ukrainian].
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