Geopathogenic zones and oncological morbidity of the population

Authors

DOI:

https://doi.org/10.14739/2310-1210.2020.6.218453

Keywords:

risk factors, cancer, incidence

Abstract

 

The aim of the work is to establish the effect of a geopathogenic zone on the cancer incidence in the population.

Materials and methods. Over a 12-year period, the oncological incidence in the population has been studied. The main group of the population (149.6 thousand) lives in the Orikhiv-Pavlograd suture zone of the Ukrainian crystalline shield. The control group of the population (129.5 thousand) lives in the Azov coastal plain. We evaluated the odds ratio (ОR), the etiological risk of morbidity (ЕF), and the relative risk with a 95 % confidence interval. Statistical processing was performed by means of the statistical analysis software package based on Microsoft Excel.

Results. Orikhiv-Pavlograd suture zone with its discontinuous faults of the lithosphere between the Azov and Mid-Dnipro microcontinents is a powerful geomagnetic territory. Its specific risks include abnormal electrical conductivity, increased EMF, radon. An increased risk of living in the indicated geopathogenic zone is indicated by the accumulation of toxic substances (Zn, Cr, Ni, Co, Mo) and high-energy fluids on fault barriers. Residents of the suture zone of discontinuous faults of the Ukrainian crystalline shield compared with the control zone demonstrate a higher incidence of malignant neoplasms (368.7 cases/100 thousand against 295.2 cases/100 thousand; P < 0.01). Living in a geopathogenic zone increases the risk of cancer both among the entire population (OR 1.4; 95 % CI 1.1–2.2, P < 0.05), and for the employable (OR 1.7; 95 % CI 1.1–2.6, P < 0.05) and older (OR 1.5; 95 % CI 1.1–2.3, P < 0.05) citizens. The etiological share of the geopathogenic factor in the development of cancer is the largest in the employable population (EF 32.7 %, 95 % CI 28.1–44.2, P < 0.05).

Conclusion. Natural geological zones as a constantly acting factor on the human body differ significantly in geophysical and geochemical properties. In the suture zone of the Ukrainian crystalline shield, compared with the Azov coastal plain, the geopathogenic influence is significantly higher. A higher incidence of malignant neoplasms both among the entire population, the employable population, and among the older age is recorded there.

References

Garetskii, R. G., & Karataev, G. I. (2015). Ekologo-tektonicheskaya sereda Belarusi [Ecological and tectonic environment of Belarus]. Belarus. navuka. [in Russian].

Selinus, O. (Ed.). (2013). Essentials of Medical Geology. Springer Netherlands. https://doi.org/10.1007/978-94-007-4375-5

Hrebniak, M. P., Shchudro, S. A., Holovkova, T. A., & Fedorchenko, R. A. (2016). Medychna ekolohiia [Medical ecology] (2nd ed.). Aktsent. [in Ukrainian].

Alekhin, V. I., & Shagrova, A. A. (2009). Formy proyavleniya razlomnykh zon Priazovskogo geobloka UShch v raznovozrastnykh kompleksakh porod i rudonosnost' [Manifestation forms of fault zones in the Priazovsky geoblock of the Ukrainian Shield in mixed age rock complexes and ore content]. Naukovi pratsi UkrNDMI NAN Ukrainy, (5, pt. 2), 305-315. [in Russian].

Alekhin, V. I. (2004). Razlomy zemnoi kory kak zony ekologicheskogo riska [Fault Lines Beneath the Earth as Areas of Environmental Risk]. Heoloho-mineralohichnyi visnyk, (1), 35-40. [in Russian].

Burakhovich, T. K., Nikolaev, I. Yu., Sheremet, E. M., & Shirkov, B. I. (2015). Geoelektricheskie anomalii Ukrainskogo shchita i ikh svyaz' s rudoproyavleniyami poleznykh iskopaemykh [Geoelectric anomalies of the Ukrainian shield and their relation to mineral occurrences]. Geofizicheskii zhurnal, 37(6), 42-63. [in Russian].

Agadzhanyan, N. А., & Makarova, I. I. (2005). Magnitnoe pole Zemli i organizm cheloveka [Earth magnetic field and human organism]. Ekologiya cheloveka, (9), 3-9. [in Russian].

Aleksandrov, V. V. (2010). Ekologicheskaya rol' elektromagnetizma [The ecological role of electromagnetism]. Izd-vo SPbGPU. [in Russian].

Burakhovych, T. K., & Usenko, O. V. (2013). Anomalii elektroprovodnosti v zonakh anortozitovogo i shchelochnogo magmatizma Ukrainskogo shchita [Conductivity anomalies in the zones of anartozit and alkaline magmatism on the Ukrainian Shield]. Heodynamika, (2), 109-111. [in Russian].

Vafin, R. A. (2003). Zdorov'e i magnitnoe pole [Health and magnetic field]. Master Lain. [in Russian].

Maslov, O. N. (2004). Ekologicheskii risk i elektromagnitnaya bezopasnost' [Environmental risk and electromagnetic safety]. IRIAS. [in Russian].

Rybakov, Yu. L. (2013). Obshchee vozdeistvie na organizm slabogo nizkochastotnogo vikhrevogo magnitnogo polya pri razvitii opukholevogo protsessa. (Avtoref. dis. … kand. biol. nauk). [The general effect on the body of a weak low-frequency vortex magnetic field during the development of a tumor process]. (Extended abstract of candidate’s thesis). Moscow. [in Russian].

Anosov, V. N., & Trukhan, E. M. (2003). Novyi podkhod k probleme vozdeistviya slabykh magnitnykh polei na zhivye ob"ekty [A new approach to the problem of the effect of weak magnetic fields on living objects]. Doklady RAN, 392(5), 689-693. [in Russian].

Caplan, L. S., Schoenfeld, E. R., O'Leary, E. S., & Leske, M. C. (2000). Breast Cancer and Electromagnetic Fields-A Review. Annals of Epidemiology, 10(1), 31-44. https://doi.org/10.1016/s1047-2797(99)00043-5

Carey, L. A., Perou, C. M., Livasy, C. A., Dressler, L. G., Cowan, D., Conway, K., Karaca, G., Troester, M. A., Tse, C. K., Edmiston, S., Deming, S. L., Geradts, J., Cheang, M. C., Nielsen, T. O., Moorman, P. G., Earp, H. S., & Millikan, R. C. (2006). Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study. JAMA, 295(21), 2492-2502. https://doi.org/10.1001/jama.295.21.2492

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. (2016). Outdoor air pollution. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 109. https://www.ncbi.nlm.nih.gov/books/NBK368024/

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. (2012). Radiation. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 100D. https://www.ncbi.nlm.nih.gov/books/NBK304362/

Kuzin, A. M. (2014). O flyuidnoi sostavlyayushchei protsessa obrazovaniya zon treshchinovatosti i razryvnykh narushenii [Concerning the fluid component in the formation process of fractures and faults]. Geologiya, geofizika i razrabotka neftyanykh i gazovykh mestorozhdenii, (5), 43-50. [in Russian].

Kuzin, A. M. (2018). Flyuidno-tektonicheskaya zonal'nost' v zemnoi kore po dannym seismicheskikh nablyudenii. In Problemy tektoniki i geodinamiki zemnoi kory i mantii [Problems of tectonics and geodynamics of the earth's crust and mantle] (Vol. 2, pp. 344-347). GEOS. [in Russian].

How to Cite

1.
Hrebniak MP, Kirsanova OV, Taranov VV. Geopathogenic zones and oncological morbidity of the population. Zaporozhye Medical Journal [Internet]. 2020Dec.9 [cited 2024Jun.22];22(6). Available from: http://zmj.zsmu.edu.ua/article/view/218453

Issue

Section

Original research