Influence of antimicrobial components of the hydroxyapatite based biocomposites on microorganisms adhesion

Authors

  • L. B. Sukhodub
  • T. P. Osolodchenko
  • G. E. Khrіstyan
  • L. G. Shtiker
  • G. M. Kozubova
  • N. M. Shulga
  • V. V. Nevmerzhitskyy
  • V. V. Kazmirchuk

DOI:

https://doi.org/10.14739/2310-1210.2014.2.25521

Keywords:

microorganism, adhesion, hydroxyapatite, chitosan, silver

Abstract

Adhesion of E. coli ATCC 25922 and S. aureus ATCC 25923 to the formalin-treated erythrocytes, influenced by the biomaterial, based on the hydroxyapatite with the content of silver ions and chitosan was studied. As a control was chosen hydroxyapatite without impurities. Results of the experiment showed that the addition of silver ions and chitosan to the biomaterial reduces by 40% and 22–39%, respectively, adhesive microorganism index (AMI) of the E. coli АТСС 25922, compared with control. Adhesive microorganism index of S. aureus ATCC 25923 was reduced for 23% and 27% under action of silver ions and chitosan respectively.

 

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How to Cite

1.
Sukhodub LB, Osolodchenko TP, Khrіstyan GE, Shtiker LG, Kozubova GM, Shulga NM, Nevmerzhitskyy VV, Kazmirchuk VV. Influence of antimicrobial components of the hydroxyapatite based biocomposites on microorganisms adhesion. Zaporozhye Medical Journal [Internet]. 2014Jun.19 [cited 2024Nov.2];16(2). Available from: http://zmj.zsmu.edu.ua/article/view/25521

Issue

Section

Problems of pharmacy