Modern scientific views on the problem of pathoplastycs of mental illnesses




The aim of the work is to study the world experience and views on the problem of pathoplastycs of mental illnesses.

In modern psychiatric clinics, the main source of pathoplastic impact are exogenous-intoxication and exogenous-organic effects. The clinical definition of the concept of pathoplastic impact is significantly expanding by some authors, breaking down the boundaries of such clinical phenomena as comorbidity, background, therapeutic pathomorphosis and others. As a result of this approach, erroneous conclusions are drawn about the presence of pathoplastic influence of personal, clinical and anamnestic, socio-demographic and cultural characteristics on the manifestations of most mental and behavioral disorders. Thus, it is impractical to expand the range of factors that referred to as factors of pathoplastic influence, when in fact they are not.

Conclusions. The problem of pathoplastycs of mental illnesses is the least studied aspect of modern clinic. The inconsistency or inappropriateness of this concept application does not contribute to its accurate assessment. Changes in the clinical manifestations of mental illnesses resulting from pathoplastic influences complicate nosological diagnostics, leading to therapeutic resistance, worsening prognosis and social maladjustment of patients. These circumstances emphasize the relevance of a comprehensive study on the phenomenon of pathoplastycs of mental illnesses/pathological conditions.

Author Biographies

V. V. Chuhunov, Zaporizhzhia State Medical University, Ukraine

MD, PhD, DSc, Professor, Head of the Department of Psychiatry, Psychotherapy, General and Medical Psychology, Narcology and Sexology

M. Ye. Khomitskyi, Zaporizhzhia State Medical University, Ukraine

MD, PhD, DSc, Associate Professor of the Department of Psychiatry, Psychotherapy, General and Medical Psychology, Narcology and Sexology


Chuhunov, V. V., & Gorodokin, A. D. (2017). Fenomen psevdopatomorfoza psihicheskoj patologii [The phenomenon of pseudopathomorphosis of mental pathology]. Ukrainskyi visnyk psykhonevrolohii, 25(1), 161. [in Russian].

Pidlubnyi, V. L. (2021). Prohnostychne ta sotsialno-ekonomichne znachennia vykorystannia systemnoi modeli otsiniuvannia psykhichnoho zdorovia [Prognostic and socio-economic significance of using the mental health assessment system model]. Zaporozhye medical journal, 23(2), 286-292. [in Ukrainian].

Zhang, A., Wang, K., & DuVall, A. S. (2021). Examining the Pathoplastic Moderating Role of Education on the Association between Depressive Mood and Self-Rated Health among Cancer Survivors: A Population-Based Study. Current oncology, 28(5), 4042-4052.

Chuhunov, V. V. (2015). Genez, komorbidnost', patoplastika i fon psikhicheskikh zabolevanii [Genesis, komorbidity, patoplastic and background mental diseases]. Muzhskoe zdorov'e, gendernaya i psikhosomaticheskaya meditsina, (1-2), 57-65. [in Russian].

Kozeratska, O. A. (2018). Obgruntuvannia kryteriiv obmezhenoi osudnosti v osib, yaki skoily kryminalni seksualni pravoporushennia [Criteria for limited sanity in persons who have committed criminal sexual offenses]. Psykhosomatychna medytsyna ta zahalna praktyka, 3(1), e0301102.

Segerstrom, S. C. (2020). Personality and Incident Alzheimer's Disease: Theory, Evidence, and Future Directions. The journals of gerontology. Series B, Psychological sciences and social sciences, 75(3), 513-521.

Graham, E. K., James, B. D., Jackson, K. L., Willroth, E. C., Boyle, P., Wilson, R., Bennett, D. A., & Mroczek, D. K. (2021). Associations Between Personality Traits and Cognitive Resilience in Older Adults. The journals of gerontology. Series B, Psychological sciences and social sciences, 76(1), 6-19.

Beauchaine, T. P., Constantino, J. N., & Hayden, E. P. (2018). Psychiatry and developmental psychopathology: Unifying themes and future directions. Comprehensive psychiatry, 87, 143-152.

Gordon-Smith, K., Perry, A., Di Florio, A., Forty, L., Fraser, C., Casanova Dias, M., Warne, N., MacDonald, T., Craddock, N., Jones, L., & Jones, I. (2020). Symptom profile of postpartum and non-postpartum manic episodes in bipolar I disorder: a within-subjects study. Psychiatry research, 284, 112748.

Perry, A., Gordon-Smith, K., Jones, L., & Jones, I. (2021). Phenomenology, Epidemiology and Aetiology of Postpartum Psychosis: A Review. Brain sciences, 11(1), 47.

Lewis, K., Di Florio, A., Forty, L., Gordon-Smith, K., Perry, A., Craddock, N., Jones, L., & Jones, I. (2018). Mania triggered by sleep loss and risk of postpartum psychosis in women with bipolar disorder. Journal of affective disorders, 225, 624-629.

Talevi, D., Collazzoni, A., Rossi, A., Stratta, P., Mazza, M., Pacitti, F., Costa, M., Crescini, C., & Rossi, R. (2020). Cues for different diagnostic patterns of interpersonal violence in a psychiatric sample: an observational study. BMC psychiatry, 20(1), 196.

Smashna, O. Ye. (2010) Syndromohenez paranoidnoi formy shyzofrenii, komorbidnoi z somatychnoiu patolohiieiu [Syndromogenezis of paranoid form of schizophrenia, comorbidity with somatic illnesses (Review of literature)]. Ukrainskyi visnyk psykhonevrolohii, 18(1), 62-66. [in Ukrainian].

Newton, J. R. (2019). Borderline personality disorder and eating disorders: a trans-diagnostic approach to unravelling diagnostic complexity. Australasian psychiatry, 27(6), 556-558.

Al-Beltagi, M. (2021). Autism medical comorbidities. World journal of clinical pediatrics, 10(3), 15-28.

Yurieva, L. M., Nosov, S. H., Mamchur, O. I., Nikolenko, A. Ie., Ohorenko, V. V., Shusterman, T. I. & Yerchkova, N. O. (2017). Kryzovi stany v suchasnykh umovakh: diahnostyka, korektsiia ta profilaktyka [Crisis conditions in modern conditions: diagnosis, correction and prevention]. Kyiv: Halereia Prynt. [in Ukrainian].

Kydon, P. V. (2019). Kliniko-psykhopatolohichni ta patopsykholohichni kharakterystyky patsiientiv z paranoidnoiu shyzofreniieiu, poiednanoiu z vzhyvanniam kanabinoidiv [Clinical and psychopathological and pathopsychological characteristics of patients with paranoid schizophrenia combined with cannabinoid use]. Extended abstract of candidate`s thesis. Kharkiv. [in Ukrainian].



How to Cite

Chuhunov VV, Khomitskyi MY. Modern scientific views on the problem of pathoplastycs of mental illnesses. Zaporozhye medical journal [Internet]. 2022Aug.1 [cited 2024Feb.24];24(4):470-3. Available from: