Myelodysplastic syndrome during pregnancy




pregnancy, myelodysplastic syndrome, anemia, delivery, complications


The aim. To highlight such a rare pathology as myelodysplastic syndrome in pregnant women, provide recommendations for treatment, management, and delivery in such patients according to modern literature, and share own experience of successful pregnancy and delivery management in two women with this pathology.

Conclusions. Myelodysplastic syndrome is extremely rare in pregnant women, and the disease is associated with an increased risk of complications for both mother and fetus. The issue of planning and management of pregnancy in patients with this disease should be decided jointly by hematologists and obstetrician-gynecologist after a thorough comprehensive examination clarifying the state of bone marrow hematopoiesis. Pregnancy and delivery should be managed in a highly qualified institution with a multidisciplinary approach and the ability to monitor hemogram, dynamic monitoring of the fetus, adequate and timely supply of blood components.

Author Biographies

V. I. Medved, SI “Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”, Kyiv

MD, PhD, DSc, Professor, Head of the Department of Internal Pathology of Pregnancy

І. М. Hrytsai, SI “Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”, Kyiv

MD, PhD, Researcher of the Department of Internal Pathology of Pregnancy

A. Ye. Husieva, SI “Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”, Kyiv

MD, Junior Researcher of the Department of Internal Pathology of Pregnancy


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How to Cite

Medved VI, Hrytsai ІМ, Husieva AY. Myelodysplastic syndrome during pregnancy. Zaporozhye Med J [Internet]. 2022Oct.22 [cited 2023Dec.5];24(5):630-4. Available from:



Case Reports