Application of infrared-beam laser therapy in the postoperative period in patients with nodular toxic goiter

Authors

DOI:

https://doi.org/10.14739/2310-1210.2022.5.259568

Keywords:

nodular toxic goiter, infrared laser, surgical, treatment

Abstract

The question of postoperative management for patients with nodular toxic goiter (NTG) using an infrared-wave laser remains poorly investigated and highly debatable, which creates conditions for further investigation of this issue.

Aim. To evaluate the results of infrared-beam laser therapy in patients with NTG in the early and long-term postoperative periods after organ-preserving surgical interventions and thyroidectomies.

Materials and methods. The main group of 35 (50.7 %) patients was examined after additional postoperative infrared-beam laser therapy (1–3 courses) while the comparison group of 34 (49.3 %) patients did not receive this treatment.

Results. Thyroidectomy prevailed in the structure of surgeries in the main group (20 (57.1 %) cases). Organ-sparing surgeries were performed in 15 (42.9 %) patients. In the comparison group, 18 (52.9 %) thyroidectomies and 16 (47.1 %) thyroid resections were performed.

Conclusions. Almost half of NTG cases (14 (41.2 %) in the main group and 15 (42.9 %) in the comparison group were unifocal mono- or lobar nodular affection which provided an opportunity to perform organ-sparing surgeries. No postoperative hypoparathyroidism was observed in the patients who underwent surgical resection. All the cases of this disorder were observed in patients after total thyroidectomy – 7 (35.0 %) in the main group and 8 (44.4 %) in the comparison group, P = 0.2956. The application of infrared-beam therapy to the postoperative area stimulated blood flow in the tissues and led to renewal of the parotid function: the parathormone level in the main group was restored in the average period of 3.5 (1.5; 6.0) months and in the comparison group – in 6.5 (3.5; 9.0) months, P = 0.0412. The postoperative use of infrared-beam laser therapy in patients with organ-sparing surgical interventions allowed reducing the dose of replacement therapy from 25.0 (25.0; 50.0) µg in the comparison group to 12.5 (12.5; 25.0) µg in the main group, P = 0.0341.

Author Biographies

S. M. Zavhorodnii, Zaporizhzhia State Medical University, Ukraine

MD, PhD, DSc, Professor, Head of the Department of General Surgery and Postgraduate Surgical Education

M. S. Gatia, Zaporizhzhia State Medical University, Ukraine

MD, Postgraduate Student of the Department of General Surgery and Postgraduate Surgical Education

M. A. Kubrak, Zaporizhzhia State Medical University, Ukraine

MD, PhD, Assistant of the Department of General Surgery and Postgraduate Surgical Education

M. B. Danyliuk, Zaporizhzhia State Medical University, Ukraine

MD, PhD, Associate Professor of the Department of General Surgery and Postgraduate Surgical Education

References

Gilbert, J. (2017). Thyrotoxicosis - investigation and management. Clinical Medicine, 17(3), 274-277. https://doi.org/10.7861/clinmedicine.17-3-274

Kurbaniyazov Z. B., Babajanov A. S., Zainiev A. F., Rakhmanov K. E., & Davlatov S. S. (2020). Factor Analysis of Relapse of Nodular Goiter. American Journal of Medicine and Medical Sciences, 10(1), 59-65. https://doi.org/10.5923/j.ajmms.20201001.13

Donangelo, I., & Suh, Y. S. (2017). Subclinical Hyperthyroidism: When to Consider Treatment - American Family Physician. American Family Physician, 95(11), 710-716. Retrieved from https://www.aafp.org/afp/2017/0601/p710.html

Biondi, B., Bartalena, L., Cooper, D. S., Hegedüs, L., Laurberg, P., & Kahaly, G. J. (2015). The 2015 European Thyroid Association Guidelines on Diagnosis and Treatment of Endogenous Subclinical Hyperthyroidism. European Thyroid Journal, 4(3), 149-163. https://doi.org/10.1159/000438750

Barczyński M. (2020). Introduction to focused issue on novel technologies in endocrine surgery. Gland surgery, 9(Suppl 2), S65-S68. https://doi.org/10.21037/gs.2020.01.10

Reeve, J., & Boden, I. (2016). The physiotherapy management of patients undergoing abdominal surgery. New Zealand Journal of Physiotherapy, 44(1), 33-49. https://doi.org/10.15619/nzjp/44.1.05

Teixeira, M. L., Vasconcellos, L. S., Oliveira, T. G., Petroianu, A., & Alberti, L. R. (2015). Prevention of abdominal adhesions and healing skin after peritoniectomy using low level laser. Lasers in surgery and medicine, 47(10), 817-823. https://doi.org/10.1002/lsm.22423

Tamhane, S., & Gharib, H. (2016). Thyroid nodule update on diagnosis and management. Clinical diabetes and endocrinology, 2, 17. https://doi.org/10.1186/s40842-016-0035-7

LiVolsi, V., & Baloch, Z. (2018). The Pathology of Hyperthyroidism. Frontiers In Endocrinology, 9, 737. https://doi.org/10.3389/fendo.2018.00737

Durante, C., Costante, G., Lucisano, G., Bruno, R., Meringolo, D., Paciaroni, A., Puxeddu, E., Torlontano, M., Tumino, S., Attard, M., Lamartina, L., Nicolucci, A., & Filetti, S. (2015). The natural history of benign thyroid nodules. JAMA, 313(9), 926-935. https://doi.org/10.1001/jama.2015.0956

Shidlovskii, V. О., Deikalo, І. М., & Shidlovskyi, О. V. (2012). Khirurhiia zobu v endemichnomu rehioni [Surgery of goiter in endemic region]. Shpytalna khirurhiia, (2), 24-29. [in Ukrainian].

Cramon, P., Winther, K. H., Watt, T., Bonnema, S. J., Bjorner, J. B., Ekholm, O., Groenvold, M., Hegedüs, L., Feldt-Rasmussen, U., & Rasmussen, Å. K. (2016). Quality-of-Life Impairments Persist Six Months After Treatment of Graves' Hyperthyroidism and Toxic Nodular Goiter: A Prospective Cohort Study. Thyroid, 26(8), 1010-1018. https://doi.org/10.1089/thy.2016.0044

Höfling, D. B., Chavantes, M. C., Buchpiguel, C. A., Cerri, G. G., Marui, S., Carneiro, P. C., & Chammas, M. C. (2018). Safety and Efficacy of Low-Level Laser Therapy in Autoimmune Thyroiditis: Long-Term Follow-Up Study. International journal of endocrinology, 2018, 8387530. https://doi.org/10.1155/2018/8387530

Zavhorodnii, S. M., Gatia, М. S., Кubrak, М. А., & Danyliuk, М. B. (2021). Khirurhichne likuvannia khvorykh na vuzlovyi toksychnyi zob [Surgical treatment of patients with nodular toxic goiter]. Zaporozhye medical journal, 23(3), 370-374. [in Ukrainian]. https://doi.org/10.14739/2310-1210.2021.3.229724

Published

2022-10-22

How to Cite

1.
Zavhorodnii SM, Gatia MS, Kubrak MA, Danyliuk MB. Application of infrared-beam laser therapy in the postoperative period in patients with nodular toxic goiter. Zaporozhye Medical Journal [Internet]. 2022Oct.22 [cited 2024Jul.3];24(5):586-90. Available from: http://zmj.zsmu.edu.ua/article/view/259568

Issue

Section

Original research