Correction of renal dysfunction in patients with the decompensated course of cirrhosis

Authors

  • A. S. Tugushev
  • D. I. Mikhantyev
  • V. V. Neshta
  • V. P. Akinshin
  • A. N. Kaulko
  • A. N. Petrash

DOI:

https://doi.org/10.14739/2310-1210.2014.3.25987

Keywords:

Liver Cirrhosis, Ascites, Bleeding, Renal Failure, Therapy, Prevention

Abstract

Aim. Elaboration of the uniform tactical installations concerning questions of rational therapy of patients with renal dysfunction in cirrhosis and its complications  is actual.

Methods and results. Effectiveness of the treatment of 48 patients with renal dysfunction was studied. As basis therapy terlipressin (Remestip)  and albumin were used. It was established that treatment of renal dysfunction improves survival rate of patients and allows to extend terms of complications development.

Conclusion. It testifies the influence of correction of renal dysfunction in patients with decompensative course of cirrhosis on duration and quality of their life.  

References

Fedos'ina, E. A., Maevskaya, M. V., & Ivashkin, V. T. (2012) Principy terapii portal'noj gipertenzii u bol'nykh cirrozom pecheni [Principles of therapy of portal hypertensia at patients with cirrhosis]. Rossijskij zhurnal gastroe`nterologii, gepatologii, koloproktologii, 5, 11–14. [in Russian].

Zavgorodnij, S. M., Tugushev, A. S., & Mikhantiev, D. I. (2013) Diahnostika, lechenie i prophilaktika pochechnoi disfunktsii pri tsyrrozi pechinky [Diagnostics, treatment and prevention of renal dysfunction at cirrhosis]. Kyiv. [in Ukrainian].

Angeli, P., Sanyal, A., Møller, S., Alessandria, C., Gadano, A., Kim, R., Sarin, S. K., & Bernardi and on behalf of the International Club of Ascites, M. (2013). Current limits and future challenges in the management of renal dysfunction in patients with cirrhosis: report from the International Club of Ascites. Liver international : official journal of the International Association for the Study of the Liver, 16-23.

Arroyo, V. (2013). A new method for therapeutic paracentesis: The automated low flow pump system. Comments in the context of the history of paracentesis. Journal of Hepatology, 58(5), 850–852. doi: 10.1016/j.jhep.2013.01.037. Epub 2013 Feb 8.

Boyer, T. D., & Kaplan, B. (2013). Renal failure and liver transplantation. Clinical Liver Disease, 2(3), 106–108. doi: 10.1002/cld.170.

Fagundes, C., Poch, E., Garcia, E., Guevara, M., Barreto, R., Ginès, P., et al. (2013). A modified acute kidney injury classification for diagnosis and risk stratification of impairment of kidney function in cirrhosis. Journal of Hepatology, 59(3), 474–481.

Fortune, B. E., & Garcia-Tsao, G. (2013). Hypervolemic hyponatremia: Clinical significance and management. Clinical Liver Disease, 2(3), 109–112. doi: 10.1002/cld.179.

Ginès, P. (2011). Pharmacological management of hepatorenal syndrome: Lessons from non-responders. Journal of Hepatology, 55(2), 268–271. doi: 10.1016/j.jhep.2011.02.006.

Guevara, M., Terra? C. &Nazar, A. (2012). Albumin for bacterial infections other than spontaneous bacterial peritonitis in cirrhosis. A randomized, controlled study. Journal of Hepatology, 57(4), 759–765. doi: 10.1016/j.jhep.2012.06.013.

Morabito, V., Novelli, G., & Jalan, R. (2013). When to use renal replacement therapy and bioartificial support for renal failure in patients with cirrhosis. Clinical Liver Disease, 2(3), 116–119. doi: 10.1002/cld.184.

Nayak, S. L., Maiwall, R., Nandwani, A., Ramanarayanan, S., Mathur, R. P., Kumar, R., et al. (2013). Management of acute kidney injury in cirrhosis. Hepatology International, 7(3), 813–819.

Ohashi, N., Kato, A., Iwakura, T., Naito, Y., Tsuji, N., Fujigaki, Y., et al. (2013). Relationship between urinary fractional excretion of sodium and life prognosis in liver cirrhosis patients. Hepatology Research, 43(11), 1156–1162.

Pascoli, M. D., Zampieri, F., Quarta, S., Sacerdoti, D., Merkel, C., Gatta, A., et al. (2011). Heme oxygenase regulates renal arterial resistance and sodium excretion in cirrhotic rats. Journal of Hepatology, 54(2), 258–264.

Salerno, F., Cazzaniga, M., & Merli, M. (2011). Diagnosis, treatment and survival of patients with hepatorenal syndrome: A survey on daily medical practice. Journal of Hepatology, 55(6), 1241–1248. doi: 10.1016/j.jhep.2011.03.012.

Singh, V., Ghosh, S., & Choudhary, N. S. (2012). Noradrenaline in the treatment of patients with hepatorenal syndrome – Back to the roots?. Journal of Hepatology, 57(4), 926.

Solà, E., Guevara, M., & Ginès, P. (2013). Current treatment strategies for hepatorenal syndrome. Clinical Liver Disease, 2(3), 136–139. doi: 10.1002/cld.209.

Downloads

How to Cite

1.
Tugushev AS, Mikhantyev DI, Neshta VV, Akinshin VP, Kaulko AN, Petrash AN. Correction of renal dysfunction in patients with the decompensated course of cirrhosis. Zaporozhye medical journal [Internet]. 2014Jul.4 [cited 2024Apr.18];16(3). Available from: http://zmj.zsmu.edu.ua/article/view/25987

Issue

No. 3 (2014): Zaporozhye medical journal

Section

Original research

License

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.  Лицензия Creative Commons
    2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
    3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)