The debut of Schamberg disease (a clinical case)

Authors

DOI:

https://doi.org/10.14739/2310-1210.2023.2.273497

Keywords:

pigmentation disorders, Schamberg purpura, pigmented purpuric dermatoses, pigmentation, skin diseases

Abstract

A group of pigmented purpuric dermatoses includes a list of skin diseases characterized by multiple petechial hemorrhages, purpura, and increased skin pigmentation (yellow, brown, or red patchy).

Schamberg disease is the most common representative of this group with a benign, chronic and recurrent course of idiopathic origin. The lesions are often asymptomatic or associated with mild pruritus, usually occurring on the lower extremities. The diagnosis is not a dilemma, as it is made based on clinical examinations and identification of the classical rash morphology, but is also emphasizing the role of a wide range of specialists in the evaluation and treatment of this pathological condition.

The aim of the study. To analyze a clinical case of the debut of Schamberg disease.

Results. Considering the sporadic nature and rarity of the disease, the clinical case of Schamberg disease diagnosed in a 53-year-old man who visited a pediatrician concerning his child’s illness is presented. The probable cause of the disease debut was a complex trigger effect (a long-term use of diclofenac sodium, drinking alcohol on the eve).

Conclusions. The report is aimed at drawing attention to Schamberg disease (Schamberg purpura) as a diagnostic and therapeutic challenge not only for general practitioners, internal medicine specialists but also for dermatologists, phlebologists, hematologists in particular.

Author Biography

S. O. Matviienko, Kharkiv National Medical University, Ukraine

MD, PhD, Associate Professor of the Department of Pediatrics 3 and Neonatology

References

Zaldivar Fujigaki, J. L., & Anjum, F. Schamberg Disease. [Updated 2022 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK560532/

Roman, C. V. (1922). Diseases of the Skin and the Eruptive Fevers. Journal of the National Medical Association, 14(4), 285-286.

Tolaymat, L., & Hall, M. R. Pigmented Purpuric Dermatitis. (2022). In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK519562/

Sharma, L., & Gupta, S. (2012). Clinicoepidemiological study of pigmented purpuric dermatoses. Indian dermatology online journal, 3(1), 17-20. https://doi.org/10.4103/2229-5178.93486

Torrelo, A., Requena, C., Mediero, I. G., & Zambrano, A. (2003). Schamberg's purpura in children: a review of 13 cases. Journal of the American Academy of Dermatology, 48(1), 31-33. https://doi.org/10.1067/mjd.2003.25

King, T., Woo, P. N., & Barbieri, A. (2016). Unilateral Petechial and Pigmentary Macules in a 12-Year-Old Boy. Pediatric dermatology, 33(3), 351-352. https://doi.org/10.1111/pde.12817

Chayed, Z., Mose, K. F., & Bygum, A. (2020). [Pigmented purpuric dermatoses]. Ugeskrift for laeger, 182(21), V12190682.

Ratnam, K. V., Su, W. P., & Peters, M. S. (1991). Purpura simplex (inflammatory purpura without vasculitis): a clinicopathologic study of 174 cases. Journal of the American Academy of Dermatology, 25(4), 642-647. https://doi.org/10.1016/0190-9622(91)70246-x

Bonnet, U., Selle, C., Isbruch, K., & Isbruch, K. (2016). Recurrent purpura due to alcohol-related Schamberg's disease and its association with serum immunoglobulins: a longitudinal observation of a heavy drinker. Journal of medical case reports, 10(1), 301. https://doi.org/10.1186/s13256-016-1065-6

Schetz, D., & Kocić, I. (2015). A new adverse drug reaction--Schamberg's disease caused by amlodipine administration--a case report. British journal of clinical pharmacology, 80(6), 1477-1478. https://doi.org/10.1111/bcp.12742

Mancano, M. A. (2016). Gastrointestinal Nodules and Bleeding with Long-Term Lanthanum Use; DRESS and Hepatotoxicity Due to Rivaroxaban; Thrombocytopenia Induced by Pentoxifylline; Amlodipine-Induced Schamberg's Disease; Varenicline-Induced Acute Liver Injury. Hospital pharmacy, 51(4), 284-287. https://doi.org/10.1310/hpj5104-284

Koçak, A. Y., Akay, B. N., & Heper, A. O. (2013). Sildenafil-induced pigmented purpuric dermatosis. Cutaneous and ocular toxicology, 32(1), 91-92. https://doi.org/10.3109/15569527.2012.702838

Abeck, D., Gross, G. E., Kuwert, C., Steinkraus, V., Mensing, H., & Ring, J. (1992). Acetaminophen-induced progressive pigmentary purpura (Schamberg's disease). Journal of the American Academy of Dermatology, 27(1), 123-124. https://doi.org/10.1016/s0190-9622(08)80826-2

Kanwar, A. J., & Thami, G. P. (1999). Familial Schamberg's disease. Dermatology, 198(2), 175-176. https://doi.org/10.1159/000018101

Tristani-Firouzi, P., Meadows, K. P., & Vanderhooft, S. (2001). Pigmented purpuric eruptions of childhood: a series of cases and review of literature. Pediatric dermatology, 18(4), 299-304. https://doi.org/10.1046/j.1525-1470.2001.01932.x

Spigariolo, C. B., Giacalone, S., & Nazzaro, G. (2021). Pigmented Purpuric Dermatoses: A Complete Narrative Review. Journal of clinical medicine, 10(11), 2283. https://doi.org/10.3390/jcm10112283

Kim, D. H., Seo, S. H., Ahn, H. H., Kye, Y. C., & Choi, J. E. (2015). Characteristics and Clinical Manifestations of Pigmented Purpuric Dermatosis. Annals of dermatology, 27(4), 404-410. https://doi.org/10.5021/ad.2015.27.4.404

Ozkaya, D. B., Emiroglu, N., Su, O., Cengiz, F. P., Bahali, A. G., Yildiz, P., Demirkesen, C., & Onsun, N. (2016). Dermatoscopic findings of pigmented purpuric dermatosis. Anais brasileiros de dermatologia, 91(5), 584-587. https://doi.org/10.1590/abd1806-4841.20165124

Schober, S. M., Peitsch, W. K., Bonsmann, G., Metze, D., Thomas, K., Goerge, T., Luger, T. A., & Schneider, S. W. (2014). Early treatment with rutoside and ascorbic acid is highly effective for progressive pigmented purpuric dermatosis. Journal of the German Society of Dermatology : JDDG, 12(12), 1112-1119. https://doi.org/10.1111/ddg.12520

Martínez Pallás, I., Conejero Del Mazo, R., & Lezcano Biosca, V. (2020). Pigmented Purpuric Dermatosis: A Review of the Literature. Dermatosis purpúricas pigmentadas. Revisión de la literatura científica. Actas dermo-sifiliograficas, 111(3), 196-204. https://doi.org/10.1016/j.ad.2019.02.013

Plachouri, K. M., Florou, V., & Georgiou, S. (2019). Therapeutic strategies for pigmented purpuric dermatoses: a systematic literature review. The Journal of dermatological treatment, 30(2), 105-109. https://doi.org/10.1080/09546634.2018.1473553

Published

2023-03-28

How to Cite

1.
Matviienko SO. The debut of Schamberg disease (a clinical case). Zaporozhye medical journal [Internet]. 2023Mar.28 [cited 2024Mar.29];25(2):184-8. Available from: http://zmj.zsmu.edu.ua/article/view/273497