Use of short carotenoids for antioxidant therapy in patients with diabetic retinopathy

Authors

  • N. G. Zavgorodnyaya
  • S. V. Mikhalchik

DOI:

https://doi.org/10.14739/2310-1210.2014.6.35863

Keywords:

Diabetic Retinopathy, Сarotenoids, Therapeutics

Abstract

Aim. In recent years there is a steady increase in the incidence of diabetes in almost all countries. The aim of this work was to study the effectiveness of Multikarenol in the complex therapy of patients with non-proliferative DR (PDR).

Methods and results. 97 patients with type II diabetes and diabetic retinopathy were examined. Patients were divided into 3 groups, depending on the stage of PDD (as recommended by WHO classification Kohner and Porta, 1991).

Conclusion. Severity of microangiopathy decrease in DR patient was detected under the influence of short carotenoids. Normalization of lipid metabolism and VEGF and PEDF factors were noted.

References

Azanabayev, M. T., & Orenburkina, O. I. (2005) Primenenie preparatov «Berlition» i «Memoplant» v lechenii diabeticheskoj retinopatii [Usage of «Berlitione» and «Memoplant» in the treatment of diabetic retinopathy]. Russkij medicinskij zhurnal. Klinicheskaya oftal'mologiya, 6(4), 169–172. [in Russian].

Dedov, I. I., Shestakova, M. A., & Milen'kaya, T. M. (2003) Sakharnyj diabet [Diabetes]. Moscow: Meditsina. [in Russian].

Kryzhanovskaya, T. V. (2003) Invalidnost' vsledstvie patologii organa zreniya u naseleniya Ukrainy v 1990–2002 godakh [Disability due to disease of the vision of the Ukrainian population in the years 1990-2002]. Oftal'mologicheskij zhurnal, 3, 23–27. [in Russian].

Kryzhanovskaya, T. V. (2005) Invalidnost' vsledstvie oftal'mologicheskikh oslozhnenij sakharnogo diabeta v Ukraine [Disability due to ophthalmic complications of diabetes in Ukraine]. Suchasní aspekty sudynno-endokrynnykh zakhvoriuvan organu zoru»; Proceedings of the 2nd International Conference, (p. 72). Kyiv. [in Russian].

Tron'ko, N. D. & Man'kovskij, B. N. (1999) Gosudarstvennaya programma «Sakharnyj diabet» [The state program «Diabetes»]. Líkuvannia ta díahnostyka, 1, 58–59. [in Russian].

Cisel'skij, Yu. V. (2004) Biokhimiya glaznykh oslozhnenij sakharnogo diabeta [Biochemistry of ocular complications of diabetes]. Oftal'mologicheskij zhurnal, 3, 11–16. [in Russian].

Zhaboedov, H. D., Scripnic, R. L., & Sidorova, M. V. (2002) Novoe v diagnostike i lechenii diabeticheskoj opticheskoj nejropatii [New in the diagnosis and treatment of diabetic optic neuropathy]. Mezhdunarodnyj medicinskij zhurnal, 1–2, 92–97. [in Russian].

Somov, Ye. Ye. (2003). Kratkoye rukovodstvo po obsledovaniyu i lecheniyu bol'nykh s sindromom «sukhogo glaza» [Quick Guide to testing and treatment for patients with the syndrome of «dry eye»]. Saint Petersburg. [in Russian].

Dobrica, Ya. V. (2004) E`ffektivnost' laferona v kompleksnom lechenii diabeticheskoj retinopatii (Dis …kand. med. nauk). [Laferon efficiency in treatment of diabetic retinopathy. (Dr. med. sci. diss.]. Khar'kov. [in Russian].

How to Cite

1.
Zavgorodnyaya NG, Mikhalchik SV. Use of short carotenoids for antioxidant therapy in patients with diabetic retinopathy. Zaporozhye Medical Journal [Internet]. 2014Dec.8 [cited 2024Nov.14];16(6). Available from: http://zmj.zsmu.edu.ua/article/view/35863

Issue

Section

Original research