Monocytes/macrophages karyologic indices in patients with chronic heart failure

Authors

  • S. V. Fedorov
  • L. Ye. Kovalchuk

DOI:

https://doi.org/10.14739/2310-1210.2015.1.38735

Keywords:

Heart Failure, Cytogenetic Analysis, Monocytes, Macrophages

Abstract

Genetic factors impact in chronic heart failure (HF) development is discussed during last decades.

The aim was to evaluate cytogenetic status of patients with ischemic HF with karyologic analyzes of monocytes/macrophages.

Methods and results. 24 patients and 12 practically healthy persons (control group) were included into the study. Internuclear bridges, perinulcear vacuolization, vacuolization and nuclear chromatin condensation were detected more frequent in patients with HF than in control.

Conclusion. This indicates proliferation activation and is initial signs of apoptosis/necrosis in observed cells.

References

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How to Cite

1.
Fedorov SV, Kovalchuk LY. Monocytes/macrophages karyologic indices in patients with chronic heart failure. Zaporozhye Medical Journal [Internet]. 2015Feb.9 [cited 2024Nov.23];17(1). Available from: http://zmj.zsmu.edu.ua/article/view/38735

Issue

No. 1 (2015): Zaporozhye Medical Journal

Section

Original research

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