Features of the neuroimaging in congenital cytomegalovirus with radiation diagnostic methods

Authors

  • O. M. Hyria

DOI:

https://doi.org/10.14739/2310-1210.2015.2.42045

Keywords:

Сytomegalovirus Infection, Newborns, Infants, Diagnosis, Neurosonography

Abstract

The specific role of infectious agents that cause disease in newborn brain belongs to cytomegalovirus. There are certain difficulties in making differential diagnosis of congenital and acquired cytomegalovirus.

Aim. In order to improve differential diagnosis there was a need to develop differential diagnostic criteria of congenital and acquired (cytomegalovirus) CM in seropositive newborns and infants with perinatal central nervous system injury.

Methods and results. 63 newborns and 60 infants 1 year old with congenital cytomegaloviral infection were studied with neurosonography. Objective morphological symptoms that can prove the presence of congenital cytomegalovirus were revealed. Among CM seropositive newborns and infants proved ability to determine patients who become infected in antenatal period.

Conclusion. These data evidence antenatal origin of the disease and are useful for justification for the appointment of etiotropic treatment.

References

Adieva, A. A. (2009) Rol` citomegalovirusnoj infekcii v patologii ploda i novorozhdennogo. Poisk novykh protivovirusnykh sredstv (Avtoref. dis…kand. med. nauk). [The role of CMV infection in the pathology of the fetus and newborn. The search for new antiviral agents] (Extended abstract of candidate’s thesis). Moscow [in Russian].

Kisteneva, L. B. (2013) Ro`l сitomegalovirusnoj infekсii v formirovanii perinatal`noj patologii [The Role of CMV Infection in Formation of Perinatal Pathology]. Detskie infekcii, 12(3), 44–47. [in Russian].

Matveev, V. A., & Shevtsova, V. V. (1998) Kliniko-laboratornaya kharakteristika i iskhody citomegalovirusnogo e`ncefalita u detey [Clinical, laboratory characteristic and outcomes of pediatric cytomegaloviral encephalitis]. Pediatriya, 77(5), 17. [in Russian].

Sanina, E. V. (1998) Osobennosti techeniya cerebral`noj formy vnutriutrobnoj citomegalovirusnoj infekcii u novorozhdyonnykh [Peculiarities of cerebral form of intrauterine CMV infection in newborns]. Proceedings of the 1st Congress of neonatologists Ukraine, (P. 23). Kharkiv [in Ukrainian].

Sidorova, I. S., Asnis, N. P., & Makarov, I. O. (1995) Ul`trazvukovaya diagnostika perinatal`nykh povrezhdeniy central`noj nervnoj sistemy u ploda i novorozhdyonnogo [Ultrasound diagnosis of perinatal lesions of the central nervous system of the fetus and newborn]. Rossijskij vestnik perinatologii i pediatrii, 3, 15–18. [in Russian].

Tischenko, V. A., Mavropulo, T. K., & Tantsiura, L. D. (1999) Kliniko-sonohrafichna kharakterystyka spetsyfichnykh vnutrishnoutrobnykh meninohoentsefalitiv [Clinical and sonographic characteristics of specific fetal meningoencephalitis]. Ukraiinskyi medychnyi almanakh, 2(1), 156. [in Ukrainian].

How to Cite

1.
Hyria OM. Features of the neuroimaging in congenital cytomegalovirus with radiation diagnostic methods. Zaporozhye Medical Journal [Internet]. 2015Apr.27 [cited 2024Nov.23];17(2). Available from: http://zmj.zsmu.edu.ua/article/view/42045

Issue

Section

Original research