Immunohistochemical peculiarities of collagen-synthesis function of the main structural components of the uterus of the fetuses from mothers with complicated pregnancies

Authors

  • V. D. Markowski
  • L. S. Kupriyanova
  • O. Yu. Degtar

DOI:

https://doi.org/10.14739/2310-1210.2015.2.42109

Keywords:

Pregnancy Complications, Fetus, Uterus, Pre-Eclampsia, Connective Tissue

Abstract

Aim. To identify features of collagen-synthesizing function of the main components of the uterus of the fetuses.

Methods and results. 41 fetuses body structure were studied. Anthropometric, organometric, histological, histochemical, immunohistochemical and statistical methods were used. Immunohistochemistry results found a violation of collagen synthesis. Collagen types I and III production was increased and collagen type IV – decreased.

Conclusion. This connective tissue peculiarities in uterus wall layers may contribute to the development of the tissue dysplasia and reproductive dysfunction in the future.

References

Znamenskaya, T. K. (2011). Prioritetnye napravleniya razvitiya perinatal'noj sluzhby v Ukraine [Development Priorities of perinatal services in Ukraine]. Neonatologіia, khіrurgіia ta perynatalna medytsyna, 2, 6–11. [in Ukrainian].

Bashmakova, N. V., Kravchenko, E. N., & Lopushanskij, V. G. (2008). Rol' prognozirovaniya intranatal'nykh faktorov riska [Role predicting intrapartum risk factors]. Akusherstvo i ginekologiya, 3, 57–61. [in Russian].

Apresyan, S. V. (2009). Beremennost' i rody pri e`kstragenital'nykh zabolevaniyakh [Pregnancy and childbirth at extragenital diseases]. V.E. Radzinsky (Ed.) Moscow: GEOTAR-Media. [in Russian].

Shunko, Ye. Ye (2011). Vprovadzhennia kontseptsii podalshoho rozvytku perynatalnoi dopomohy v Ukraini [The introduction of the concept of further development of perinatal care in Ukraine]. Neonatolohiia, khirurhiia ta perynatalna medytsyna, 1, 10–16. [in Ukrainian].

Belova, O. (2009). Prohnoz rozvytku ditei z duzhe maloiu masoiu tila pry narodzhenni: mizhnarodnyi i vitchyznianyi dosvid [Forecast for children with very low birth weight: international and domestic experience] Proceedings of the 13th Congress of Medical Students and Young Scientists, (P. 101) Ternopil. [in Ukrainian].

Subbotin, M. Ya., Laguchev, S. S., Oganesyan, Т. G., et al. (1954). Gistologcheskaya tehnika [Histological technique]. Moscow: Medgiz. [in Russian].

Kosharnyi, V. V., & Shatorna, V. F. (2009). Vykorystannia imunohistokhimichnykh metodiv doslidzhennia v embriolohii [Using immunohistochemical methods of research in embryology]. Patologіya, 2, 66–69. [in Ukrainian].

Hubіna-Vakulіk, G. I., Markovskyi, V. D., Sorokіna, I. V., Kіhtenko, O. V., Kuprіianova, L. S., Sydorenko, R. V. (2009) Patent na korysnu model «Sposіb kіlkіsnogo viznachennya vmіstu antigen in bіologіchnih tkaninah» [The method of quantitative determination of antigen content in biological tissues], u200906730. [in Ukrainian].

Atramentova, L. A., & Utevskaya, О. М. (2008). Statisticheskie metody v biologii [Statistical Methods in Biology]. Gorlovka. [in Ukrainian].

Dankovych, N. O. (2004). Osoblyvosti somatychnoi zakhvoriuvanosti, rozumovoho, psykhoemotsionalnoho ta fizychnoho rozvytku divchatok, yaki narodylys iz zatrymkoiu vnutrishnoutrobnoho rozvytku [Features somatic diseases, mental, and physical development psyhoemotsionalnoho girls who were born with intrauterine growth]. Pedіatrіia, akusherstvo ta hinekolohiia, 1, 138–140. [in Ukrainian].

Klemenov, A. V., Tkacheva, A. V., & Vertkin, A. L. (2004). Displaziya soedinitel'noj tkani i beremennost' [Connective tissue dysplasia and pregnancy]. Terapevticheskij arkhiv, 11, 80–83. [in Russian].

Nazarenko, L. G., & Neielova, O.V. (2005). Spoluchnotkanynni dysplazii – problema suchasnoho akusherstva ta perynatolohii [Fybrodisplations – the problem of modern obstetrics and perinatology]. Pedіatrіia, akusherstvo ta hinekolohiia, 6, 93–96. [in Ukrainian].

Okhapkіna, O. V. (2011). Viko-statevi osoblyvosti klinichnoho perebihu dysplastykozalezhnoi patolohii u ditei [Sexual and age features of dysplastic dependent pathology in children]. Visnyk problem biolohii i medytsyny, 2, 147–149. [in Ukrainian].

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How to Cite

1.
Markowski VD, Kupriyanova LS, Degtar OY. Immunohistochemical peculiarities of collagen-synthesis function of the main structural components of the uterus of the fetuses from mothers with complicated pregnancies. Zaporozhye Medical Journal [Internet]. 2015Apr.27 [cited 2024Jul.27];17(2). Available from: http://zmj.zsmu.edu.ua/article/view/42109

Issue

No. 2 (2015): Zaporozhye medical journal

Section

Original research

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